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CNIO researchers identify over 40 genes that predict aggressiveness of melanoma

Researchers from the Spanish National Cancer Research Centre have discovered more than 40 genes that predict the level of aggressiveness of melanoma and that distinguish it from other cancers with a poor prognosis. The discovery, published in Cancer Cell, will help to identify unique aspects of melanoma that could contribute to determine the risk of developing metastasis in patients with this disease.

28 Jun 2014

Gene study reveals the root of language development in humans

The evolution of language in humans continues to perplex scientists and linguists who study how humans learn to communicate.

28 Jun 2014

Some cancer patients with aggressive tumors may benefit from anti-inflammatory drugs

New research raises the prospect that some cancer patients with aggressive tumors may benefit from a class of anti-inflammatory drugs used to treat rheumatoid arthritis.

28 Jun 2014

Vertex receives positive opinion from European CHMP for approval of KALYDECO for cystic fibrosis

Vertex Pharmaceuticals Incorporated today announced that the European Committee for Medicinal Products for Human Use has issued a positive opinion recommending the approval of KALYDECO (ivacaftor) for people with cystic fibrosis (CF) ages 6 and older who have one of eight non-G551D gating mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

28 Jun 2014

Researchers find way to diagnose aggressiveness of oral cancer

Studying mouth cancer in mice, researchers have found a way to predict the aggressiveness of similar tumors in people, an early step toward a diagnostic test that could guide treatment, according to researchers at Washington University School of Medicine in St. Louis.

28 Jun 2014

First step toward new drugs that can transcend antibiotic resistance issues

Scientists in the United States and India have successfully modified the precursor to one of the drugs used to treat tuberculosis, an important first step toward new drugs that can transcend antibiotic resistance issues that experts consider a serious threat to global health.

28 Jun 2014

UCSB researchers explore genetic underpinnings of nerve-cell spacing

The functional organization of the central nervous system depends upon a precise architecture and connectivity of distinct types of neurons.

27 Jun 2014

Cancer drug shows promise in treating blood cell disorders

Scientists working to make gene therapy a reality have solved a major hurdle: how to bypass a blood stem cell's natural defenses and efficiently insert disease-fighting genes into the cell's genome.

27 Jun 2014

Scientists one step closer to understanding the causes of Parkinson's disease

Scientists have taken a step closer to understanding the causes of Parkinson's disease, identifying what's happening at a cellular level to potentially help develop future treatments.

27 Jun 2014

Surgical biopsies can be safely performed on selected patients with late-stage lung cancer

Researchers at UC Davis have determined that surgical biopsies can be safely performed on select patients with late-stage non-small cell lung cancer, which should enhance their access to drugs that target specific genetic mutations such as epidermal growth factor receptor (EGFR).

27 Jun 2014

Auxilium Pharmaceuticals plans to merge with QLT

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, and QLT Inc., a Canadian-based biotechnology company focused on developing innovative orphan ophthalmology products, today announced that they have entered into a definitive agreement under which Auxilium plans to merge with QLT.

26 Jun 2014

Scientists report first successful step toward vaccine that targets mutation in brain cancer

Astrocytomas and oligodendrogliomas are subtypes of a brain cancer called 'glioma'. These incurable brain tumors arise from glial cells, a type of support cell found in the central nervous system.

26 Jun 2014

FMM supports research project to investigate mitochondria-targeted therapeutic approach

The Foundation for Mitochondrial Medicine announced today that it is working with The Michael J. Fox Foundation for Parkinson's Research to support a research project led by Wolfdieter Springer, PhD, at the Department of Neuroscience at Mayo Clinic in Florida to investigate a mitochondria-targeted therapeutic approach to treating Parkinson's disease.

26 Jun 2014

Researchers compare genome sequences of malaria vectors to investigate insecticide resistance

Researchers from LSTM have exploited a natural experiment created by insecticidal pressure to determine how the most important malaria vectors - A. gambiae s.s. and A. coluzzii - respond rapidly to environmental change.

26 Jun 2014

Queen's doctor plays key role in major breakthrough to change lives of cystic fibrosis sufferers

A Queen's University doctor has played a key role in a major breakthrough to change the lives of cystic fibrosis sufferers.

26 Jun 2014

Gene partnership may be fueling cancer spread in as much as 20% of cancers

A key cancer-causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota.

25 Jun 2014

Intercalated erlotinib–eribulin ‘feasible’ without added efficacy

Erlotinib can be intercalated with the anti-tubule agent eribulin mesylate for patients with advanced non-small-cell lung cancer but it is unlikely to increase treatment efficacy in those without epidermal growth factor receptor activating mutations, research suggests.

25 Jun 2014

Study: Cohesin mutations are common in melanoma and bladder cancer

Massive sequencing of cancer genomes brings to light new genes every day that could be involved in the process of tumour formation.

25 Jun 2014

New study explores effects of immunotherapy, chemotherapy drugs on non-small cell lung cancer

A new study offered at Houston Methodist Hospital will compare an emerging immunotherapy drug to an existing chemotherapy drug and look at the effects both drugs have on the development of non-small cell lung cancer, a type of cancer which makes up about 85 percent of lung cancer cases.

24 Jun 2014

Research finding could open new opportunities for treating Huntington's disease

Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene to the inherited disease more than 20 years ago

24 Jun 2014

Mutation News and Research

CNIO researchers identify over 40 genes that predict aggressiveness of melanoma

Gene study reveals the root of language development in humans

Some cancer patients with aggressive tumors may benefit from anti-inflammatory drugs

Vertex receives positive opinion from European CHMP for approval of KALYDECO for cystic fibrosis

Researchers find way to diagnose aggressiveness of oral cancer

First step toward new drugs that can transcend antibiotic resistance issues

UCSB researchers explore genetic underpinnings of nerve-cell spacing

Cancer drug shows promise in treating blood cell disorders

Scientists one step closer to understanding the causes of Parkinson's disease

Surgical biopsies can be safely performed on selected patients with late-stage lung cancer

Auxilium Pharmaceuticals plans to merge with QLT

Scientists report first successful step toward vaccine that targets mutation in brain cancer

FMM supports research project to investigate mitochondria-targeted therapeutic approach

Researchers compare genome sequences of malaria vectors to investigate insecticide resistance

Queen's doctor plays key role in major breakthrough to change lives of cystic fibrosis sufferers

Gene partnership may be fueling cancer spread in as much as 20% of cancers

Intercalated erlotinib–eribulin ‘feasible’ without added efficacy

Study: Cohesin mutations are common in melanoma and bladder cancer

New study explores effects of immunotherapy, chemotherapy drugs on non-small cell lung cancer

Research finding could open new opportunities for treating Huntington's disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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