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Metabolic changes after gastric bypass surgery reverse within one year

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass.

17 Aug 2023

Study provides insight into aging of the brain

Most of us who've reached middle age have noticed a slowing in memory and cognition, but scientists don't have a clear picture of the molecular changes that take place in the brain to cause it.

17 Aug 2023

Klotho levels and telomere length may be associated through a coordinated downregulation of longevity factors

A new research paper was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) in Volume 15, Issue 15, entitled, "Associations between klotho and telomere biology in high stress caregivers."

17 Aug 2023

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models.

17 Aug 2023

Current methods overestimate malaria parasite multiplication rates

Current methods can vastly overestimate the rates that malaria parasites are multiplying in an infected person's blood, which has important implications for determining how harmful they could be to a host, according to a new report.

17 Aug 2023

New insights into the role of liver progenitor cells in liver cancer initiation

Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries.

17 Aug 2023

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a grant from the U.S. Department of Defense (DoD)'s Congressionally Directed Medical Research Program to target chemotherapy resistance in pancreatic cancer.

17 Aug 2023

New small molecule drug targets active state of cancer-causing KRAS mutant

A new small molecule drug helps to bind the naturally occurring cellular chaperone cyclophilin A (CYPA) to the active state of the cancer-causing mutant KRASG12C, disrupting oncogenic signaling and tumor growth in several models of human cancer.

17 Aug 2023

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.

17 Aug 2023

Study suggests antibodies triggered by COVID-19 mRNA vaccination may depend on prior infection history

Researchers evaluated distinct immune responses to mRNA and vector-based COVID-19 vaccines and natural SARS-CoV-2 infections.

17 Aug 2023

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Researchers used human transcriptomic data to differentiate the molecular mechanisms associated with two phenotypes of allergic rhinitis: rhinitis and rhinitis with asthma.

17 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

Prior vaccinations may help protect against Alzheimer's disease

Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston.

16 Aug 2023

Mitochondrial dysfunction may be a contributor to schizophrenia

Researchers at Rutgers and Emory University are gaining insights into how schizophrenia develops by studying the strongest-known genetic risk factor.

16 Aug 2023

Wristbands can harbor harmful bacteria, study finds

The COVID-19 pandemic took disinfecting to new heights. Now, a new study examining a commonly used item might convince you not to let your guard down just yet.

16 Aug 2023

Long DNA molecules reveal new scar types in HR-deficient cancers

DNA can be damaged by toxins, radiation, or even normal cell division, but human cells must continually fix DNA breaks to survive.

16 Aug 2023

New evidence bolsters possible link between e-cigarette use and increased risk of stroke

There is new evidence that bolsters a possible link between e-cigarette use and increased risk of stroke, according to researchers from the University of Colorado Boulder.

16 Aug 2023

Sulfate groups on complex sugar molecules affect brain plasticity

Can you recognize someone you haven't seen in years, but forget what you had for breakfast yesterday? Our brains constantly rearrange their circuitry to remember familiar faces or learn new skills, but the molecular basis of this process isn't well understood.

16 Aug 2023

Bioengineered nanovesicles could improve cancer treatment

Nanovesicles can be bioengineered to target cancer cells and deliver treatments directly, according to research at Binghamton University, State University of New York.

16 Aug 2023

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

New Cleveland Clinic research shows how mosquito-transmitted viruses – like Zika, West Nile, Yellow Fever and dengue viruses – hijack host cells to promote their own replication and infection.

16 Aug 2023

B Cell News and Research

Metabolic changes after gastric bypass surgery reverse within one year

Study provides insight into aging of the brain

Klotho levels and telomere length may be associated through a coordinated downregulation of longevity factors

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Current methods overestimate malaria parasite multiplication rates

New insights into the role of liver progenitor cells in liver cancer initiation

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

New small molecule drug targets active state of cancer-causing KRAS mutant

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Study suggests antibodies triggered by COVID-19 mRNA vaccination may depend on prior infection history

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Prior vaccinations may help protect against Alzheimer's disease

Mitochondrial dysfunction may be a contributor to schizophrenia

Wristbands can harbor harmful bacteria, study finds

Long DNA molecules reveal new scar types in HR-deficient cancers

New evidence bolsters possible link between e-cigarette use and increased risk of stroke

Sulfate groups on complex sugar molecules affect brain plasticity

Bioengineered nanovesicles could improve cancer treatment

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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