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Research roundup: Crowded emergency departments, expensive HIV drugs, high deductible insurance plans

Skin In The Game: How Consumer-Directed Plans Affect The Cost And Use Of Health Care -- Consumer-directed health plans, which feature lower premiums and higher deductibles than traditional plans, are designed to reduce costs by discouraging unnecessary care. This brief describes a study of more than 800,000 households that switched from a traditional employer-based plan to a consumer-based plan.

7 Jul 2012

FDA action affects companies that manufacture and distribute unapproved oxycodone drugs

The U.S. Food and Drug Administration today issued a Federal Register notice instructing companies to stop manufacturing and distributing certain unapproved drugs that contain oxycodone. The notice is part of the FDA's Unapproved Drugs Initiative to remove unapproved new drugs from the market.

6 Jul 2012

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

Eltrombopag, a drug that was designed to stimulate production of platelets from the bone marrow and thereby improve blood clotting, can raise blood cell levels in some people with severe aplastic anemia who have failed all standard therapies.

5 Jul 2012

UN food standards body agrees on new regulations to protect health of consumers across the world

The UN food standards body has agreed on new regulations - including the maximum level of melamine in liquid milk formula for babies - to protect the health of consumers across the world. Other measures adopted include new food safety standards on seafood, melons, dried figs and food labelling.

5 Jul 2012

Live zoster vaccine associated with reduced risk of HZ in patients with immune-mediated diseases

Although some have suggested that patients receiving medication for immune-mediated diseases such as rheumatoid arthritis or psoriasis may be at increased risk of herpes zoster (HZ; shingles) shortly after receipt of the vaccine, an analysis that included nearly 20,000 vaccinated Medicare beneficiaries finds that the live zoster vaccine is not associated with an increased risk of HZ shortly after vaccination in patients currently treated with biologics, and that it is associated with a significantly reduced longer-term risk of HZ in patients with an immune-mediated disease, according to a study in the July 4 issue of JAMA.

4 Jul 2012

UCLA School of Dentistry receives NIH grant to create comprehensive research training program

In recent years, faculty at the UCLA School of Dentistry have been expanding the traditional boundaries of dentistry through groundbreaking multidisciplinary research that has led to major advances in everything from stem cell science to saliva diagnostics. Now, a $5 million grant from the National Institutes of Health's National Institute of Dental and Craniofacial Research will allow the school to continue these pioneering efforts by creating a comprehensive research training program to help cultivate the next generation of dentist-scientists and oral health researchers.

4 Jul 2012

Polio elimination hindered by unvaccinated children in Pakistan and Afghanistan

Too few children have received sufficient doses of vaccine to wipe out polio in Pakistan and Afghanistan, two of only three countries in the world where endemic polio has yet to be eliminated, according to new research published Online First in The Lancet. The findings suggest that the newly introduced bivalent oral poliovirus vaccine (OPV) has the potential to eliminate polio in these countries if sufficient numbers of children could be reached by vaccination programmes.

4 Jul 2012

OraSure Technologies receives FDA approval for new in-home HIV test

The U.S. Food and Drug Administration today approved the OraQuick In-Home HIV Test, the first over-the-counter, self-administered HIV test kit to detect the presence of antibodies to human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2).

4 Jul 2012

FDA approves Lupin’s Norgestimate and Ethinyl Estradiol Tablets

Pharma major, Lupin Ltd., announced today that its subsidiary, Lupin Pharmaceuticals Inc. has received approval for its Norgestimate and Ethinyl Estradiol Tablets, 0.18 mg/0.025 mg, 0.215 mg/0.025 mg, and 0.25 mg/0.025 mg from the United States Food and Drugs Administration (FDA).

4 Jul 2012

Treating Sickle Cell Disease with L-Glutamine

By focusing on how best to help patients, researchers can sometimes find solutions that are much simpler than anticipated. That has been the guiding approach to our efforts to develop a treatment for sickle cell disease.

3 Jul 2012

CBS News: Roberts shifted view on constitutionality of individual mandate

CBS News reports that Supreme Court Chief Justice John Roberts Jr. initially sided with conservatives before he changed his mind and formed an alliance with liberals to uphold most of the health care law. Other news outlets scrutinize Roberts's historic decision.

3 Jul 2012

Three-step clinical pathway for CAP reduces length of hospital stay

A three-step pathway helps to reduce the duration of intravenous antibiotic treatment in hospitalized patients with community-acquired pneumonia, show study findings published in the Archives of Internal Medicine.

2 Jul 2012

Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB

Janssen Research & Development, LLC today announced it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking accelerated approval for the use of the investigational drug bedaquiline (TMC207) as an oral treatment, to be used as part of combination therapy for pulmonary, multi-drug resistant tuberculosis (MDR-TB) in adults.

2 Jul 2012

Clinical results for Teva's biologic oncology candidates presented at MASCC/ISOO 2012

Teva Pharmaceutical Industries Ltd. announced today the presentation of clinical results for its biologic oncology candidates, lipegfilgrastim and balugrastim, at the Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO) 2012 International Symposium on Supportive Care in Cancer being held in New York June 28-30.

2 Jul 2012

How the High Court's decision contributes to Obama's legacy

News outlets report on how the health law, and the Supreme Court's review of it, will be important parts of President Barack Obama's place in history.

30 Jun 2012

Eight-year trends in pediatric drug use examined

A review of US outpatient pediatric drug use over the past 8 years shows a decrease in systemic antibiotic, allergy, pain, and depression prescriptions, and an increase in asthma, attention deficit/hyperactivity disorder, and contraceptive prescriptions.

29 Jun 2012

Liraglutide efficacy in Japanese patients “easy” to predict

Liraglutide therapy is an effective alternative to basal-supported oral therapy for some Japanese patients with diabetes, while it is completely ineffective for others, report researchers.

29 Jun 2012

A.P. Pharma announces additional data from APF530 Phase 3 study on CINV

A.P. Pharma, Inc., a specialty pharmaceutical company, today announced additional data from the Company's Phase 3 study of APF530 for the prevention of chemotherapy-induced nausea and vomiting (CINV).

29 Jun 2012

Lexicon announces results from two initial trials of LX4211 for type 2 diabetes

Lexicon Pharmaceuticals, Inc. announced today the publication of results from two initial trials of LX4211 in patients with type 2 diabetes in the online edition of the journal Clinical Pharmacology & Therapeutics.

29 Jun 2012

RapidChek- SELECT Salmonella highly sensitive to the presence of S. Typhi vaccine in stool

Salmonella Typhi (S. Typhi) is the causative agent of typhoid fever, a serious health threat resulting in some 22 million new cases yearly and approximately 217,000 fatalities. A number of novel vaccine candidates using live attenuated strains of Salmonella are being developed, but care must be taken to ensure the bacteria are not excreted into the environment following vaccination.

29 Jun 2012

Oral News and Research

Research roundup: Crowded emergency departments, expensive HIV drugs, high deductible insurance plans

FDA action affects companies that manufacture and distribute unapproved oxycodone drugs

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

UN food standards body agrees on new regulations to protect health of consumers across the world

Live zoster vaccine associated with reduced risk of HZ in patients with immune-mediated diseases

UCLA School of Dentistry receives NIH grant to create comprehensive research training program

Polio elimination hindered by unvaccinated children in Pakistan and Afghanistan

OraSure Technologies receives FDA approval for new in-home HIV test

FDA approves Lupin’s Norgestimate and Ethinyl Estradiol Tablets

Treating Sickle Cell Disease with L-Glutamine

CBS News: Roberts shifted view on constitutionality of individual mandate

Three-step clinical pathway for CAP reduces length of hospital stay

Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB

Clinical results for Teva's biologic oncology candidates presented at MASCC/ISOO 2012

How the High Court's decision contributes to Obama's legacy

Eight-year trends in pediatric drug use examined

Liraglutide efficacy in Japanese patients “easy” to predict

A.P. Pharma announces additional data from APF530 Phase 3 study on CINV

Lexicon announces results from two initial trials of LX4211 for type 2 diabetes

RapidChek- SELECT Salmonella highly sensitive to the presence of S. Typhi vaccine in stool

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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