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Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

Study yields new knowledge about genes responsible for IgG production and release

A collaboration led by UCLA and the Seattle Children's Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.

14 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

Kidney cancer study reveals new findings about MiTF family gene mutations

A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.

14 Aug 2023

Scientists uncover new molecular targets for cardiovascular regulation

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have uncovered new molecular targets on a cell receptor that play a major role in cardiovascular regulation.

14 Aug 2023

New insights into how coronaviruses invade cells

Unexpected new insights into how COVID-19 infects cells may help explain why coronaviruses are so good at jumping from species to species and will help scientists better predict how COVID-19 will evolve.

14 Aug 2023

The role of self-extracellular nucleic acids in neuroinflammation

Researchers explore the role of self-extracellular nucleic acids in diseases like stroke, multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease.

14 Aug 2023

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Scientists have developed a lymph node-targeted multi-epitope subunit vaccine that induces strong humoral and cellular immune responses against EBV in mice.

14 Aug 2023

How does particulate matter air pollution contribute to antibiotic resistance?

Researchers explore the role of particulate matter within the environment to facilitate the spread of genetic elements responsible for antibiotic resistance.

14 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

How complementarity-determining region (CDR) loops in the single-chain variable fragment (scFv) influence chimeric antigen receptor (CAR)-T cell behavior.

14 Aug 2023

Salk scientists find new immunotherapy treatment for glioblastoma

Glioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous tendrils into the brain that make surgical tumor removal extremely difficult or impossible.

11 Aug 2023

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023