Neuroscience News and Research

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Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

Researchers in the Adult Genetic Epilepsy Program of the Krembil Neuroscience Centre have discovered a gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease.

16 Oct 2015

New breakthrough advances our understanding of how brain detects, prevents dehydration

Scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) and Duke University have made a breakthrough that advances our understanding of how the brain detects and prevents dehydration.

16 Oct 2015

Scientists use new technology to create gene expression map of inner ear cell development

Using a sensitive new technology called single-cell RNA-seq on cells from mice, scientists have created the first high-resolution gene expression map of the newborn mouse inner ear.

16 Oct 2015

Researchers introduce free iOS app to learn about autism in young children

A team of researchers and software developers from Duke University and the Duke Medical Center has introduced a free iOS app to learn more about autism in young children living around the world.

16 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

Researchers report weak association between brain size and IQ

As early as 1836, the German physiologist and anatomist Friedrich Tiedemann, in an article in the Philosophical Transactions, expressed his opinion that "there is undoubtedly a connection between the absolute size of the brain and the intellectual powers and functions of the mind". With the advent of brain imaging methods (e.g., MRI, PET), reliable assessments of in-vivo brain volume and investigations of its association with IQ are now possible.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

Researchers one step closer to finding effective drug for alcohol dependence

Researchers at Karolinska Institutet and the Sahlgrenska Academy in Sweden might be one step closer to finding an effective drug for alcohol dependence. In two separate studies, they show that the so-called dopamine stabilizer OSU6162 can reduce the craving for alcohol in alcohol dependent people and normalises the level of dopamine in the brain reward system of rats that have consumed alcohol over a long period of time.

14 Oct 2015

MIT neuroscientists discover brain circuit that controls sleep

Sleep is usually considered an all-or-nothing state: The brain is either entirely awake or entirely asleep. However, MIT neuroscientists have discovered a brain circuit that can trigger small regions of the brain to fall asleep or become less alert, while the rest of the brain remains awake.

14 Oct 2015

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Researchers at the University of Washington have used a noninvasive light-based imaging technology to literally see inside the living brain, providing a new tool to study how diseases like dementia, Alzheimer's, and brain tumors change brain tissue over time.

13 Oct 2015

Research findings open up new avenues for treatment of people with anorexia nervosa

When people with anorexia nervosa decide what to eat, they engage a part of the brain associated with habitual behavior. This finding by researchers at Columbia University Medical Center, New York State Psychiatric Institute, the Mortimer B. Zuckerman Mind Brain Behavior Institute, and New York University was published today in Nature Neuroscience.

13 Oct 2015

Females with mild closed-head brain injury more likely to misuse alcohol later in life

Girls who suffer a concussive bump on the head in childhood could be at increased risk for abusing alcohol as adults, a new study suggests.

13 Oct 2015

Researchers find how different neurons work together to reduce responses to frequent sounds

Being able to understand speech is essential to our evolution as humans. Hearing lets us perceive the same word even when spoken at different speeds or pitches, and also gives us extra sensitivity to unexpected sounds. Now, new studies from the Perelman School of Medicine at the University of Pennsylvania clarify how these two crucial features of audition are managed by the brain.

12 Oct 2015

Study shows that IVIG could prevent brain atrophy, delay onset of Alzheimer's disease

In a Sutter Institute of Medical Research study published this month in the Journal of Neurology, Neurosurgery, and Psychiatry, the blood product intravenous immunoglobulin, or IVIG, was found to reduce brain atrophy and cognitive decline in patients in the early, pre-dementia phase of Alzheimer's disease.

12 Oct 2015

High dose flu vaccines significantly reduce hospitalization risk during influenza season

In the largest nursing home study to date on the effect of high dose flu vaccine, researchers found that shots with four times the strength of standard flu shots significantly reduced the risk of being hospitalized during the influenza season. There was a 1.2 percent difference (19.7 percent versus 20.9 percent) in admission for the group that received the high dose vaccine compared to the one that received the standard dose vaccine.

12 Oct 2015

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Chronic pain results from disease or trauma to the nervous system. Damaged nerve fibres with heightened responses to normal stimuli send incorrect messages to pain centres in the brain. This phenomenon, called "peripheral and central sensitization" is one of the key mechanisms involved in the condition which touches people with diabetes, cancer, and those suffering from multiple sclerosis, among others.

12 Oct 2015

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Three phase III studies being presented at the European Committee for Treatment Research in Multiple Sclerosis congress demonstrate that treating MS with ocrelizumab reduces relapse rate and delay onset of disability progression compared to interferon beta-1a in relapsing forms of MS and disability progression in primary progressive MS compared to placebo.

12 Oct 2015

Neuroscience News and Research

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

BET protein family plays key role in regulation of normal neuronal development and function

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

New breakthrough advances our understanding of how brain detects, prevents dehydration

Scientists use new technology to create gene expression map of inner ear cell development

Researchers introduce free iOS app to learn about autism in young children

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Researchers report weak association between brain size and IQ

Having a high stress job may increase risk of stroke

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

Researchers one step closer to finding effective drug for alcohol dependence

MIT neuroscientists discover brain circuit that controls sleep

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Research findings open up new avenues for treatment of people with anorexia nervosa

Females with mild closed-head brain injury more likely to misuse alcohol later in life

Researchers find how different neurons work together to reduce responses to frequent sounds

Study shows that IVIG could prevent brain atrophy, delay onset of Alzheimer's disease

High dose flu vaccines significantly reduce hospitalization risk during influenza season

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Event guide: 2nd Neuroscience Innovation Partnering & Licensing Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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