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Study determines how fibroblasts play a role in tumor's ability to generate anti-HER2 therapy resistance

A study led by researchers at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) has determined the role that fibroblasts, the cells that contribute to tissue formation, play in a tumor's ability to generate resistance to the most common biological treatment for HER2.

14 Oct 2022

Study reveals why viral infections are less frequent but more severe in individuals with Down syndrome

Individuals with Down syndrome have less-frequent viral infections, but when present, these infections lead to more severe disease.

14 Oct 2022

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

In a new study, researchers discussed the therapeutic potential of Panax ginseng for COVID-19 (coronavirus disease 2019)-induced neurological diseases.

14 Oct 2022

CCA's research initiative aims to identify progress, challenges in the lives of people with celiac disease

Twenty years after the first baseline survey of Canadians living with celiac disease was conducted, the Canadian Celiac Association (CCA) is mounting a major research initiative to identify progress made and continuing challenges surrounding life with the condition.

14 Oct 2022

Chinese study determines the real-world effectiveness of COVID-19 vaccines

A recent study aimed to determine the real-world effectiveness of COVID-19 vaccines against SARS-CoV-2 infection.

14 Oct 2022

Rapidly fading antibody levels in recovered COVID-19 patients associated with plasma metabolites

A study led by Hong Kong Baptist University (HKBU) has revealed the association between rapidly fading antibody levels in some recovered COVID-19 patients and a high plasma concentration of a metabolite called glycylproline (gly-pro) and its producing enzyme.

14 Oct 2022

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer's disease

Researchers have puzzled over the neurodegenerative disorder Alzheimer's disease for decades, but treatments to stop or reverse the disease's effects on the brain have remained elusive.

13 Oct 2022

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a leading infectious threat to public health worldwide.

13 Oct 2022

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Researchers examined single clones of SARS-CoV-2-specific memory B cells to understand their adaptability and fate.

13 Oct 2022

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Researchers performed a ProP-PD (proteomic peptide phage display) analysis to identify peptides from intrinsically disordered human (host) proteome regions that bind with SARS-CoV-2 genome-encoded folded protein domains (PDs).

13 Oct 2022

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

In a new study, researchers visualized the mechanism of action and inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 13 (NSP13) at high spatio-temporal resolution.

13 Oct 2022

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Researchers developed a human endogenous retrovirus (HERV)-enveloped recombinant baculoviral DNA vaccine to target the SARS-CoV-2 Delta variant, and tested its cross-protection efficacy using mice models.

13 Oct 2022

Evaluating SARS-CoV-2 rapid antigen tests using saliva specimen

In a new study, researchers evaluated a rapid antigen test (RAT) that used saliva specimens to detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Oct 2022

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis.

13 Oct 2022

Understanding the potential applications of stem cell research

To mark Stem Cell Awareness Day on October 12, 2022, COST is highlighting a network of researchers working to foster greater understanding about stem cell research and potential applications for millions of people suffering from incurable diseases and injury.

12 Oct 2022

Protein C News and Research

Study determines how fibroblasts play a role in tumor's ability to generate anti-HER2 therapy resistance

Study reveals why viral infections are less frequent but more severe in individuals with Down syndrome

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

CCA's research initiative aims to identify progress, challenges in the lives of people with celiac disease

Chinese study determines the real-world effectiveness of COVID-19 vaccines

Rapidly fading antibody levels in recovered COVID-19 patients associated with plasma metabolites

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer's disease

Chinese scientists reveal a previously undefined pathway by which Mtb counteracts host immunity

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Motif-based SARS-CoV-2 protein-human protein interactions as potential antiviral target sites

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Evaluating SARS-CoV-2 rapid antigen tests using saliva specimen

What is the association between interferon genes and complement regulatory protein expressions in SARS-CoV-2 infections?

Understanding the potential applications of stem cell research

Advanced cryo-electron microscope reveals how poliovirus takes over human cells

Cardiovascular risk factors – not preexisting heart disease – are the main contributors to COVID-19 death

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

Scientists reveal the architecture of the inner ear responsible for hearing

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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