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Therapeutic small molecules safely prevent blood clots without excessive bleeding

It may be possible to disrupt harmful blood clots in people at risk for heart attack or stroke without increasing their risk of bleeding, according to a new study published in Nature Communications.

31 May 2017

Brain changes after stroke may lead to increased preference for alcohol, research suggests

Brain changes after stroke may lead to increase in alcohol-seeking behavior, at least in animal models, according to research published Wednesday in the journal Scientific Reports.

31 May 2017

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high-risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center

31 May 2017

Scientists could be one step closer to developing vaccines against viruses

Scientists could be one step closer to developing vaccines against viruses such as Zika, West Nile or HIV, according to Penn State College of Medicine researchers.

31 May 2017

New study reveals how brain's opioids modulate responses towards other people's pain

A new Finnish research reveals how brain's opioids modulate responses towards other people's pain.

31 May 2017

Research findings may pave way for miracle drug to treat narcolepsy

Narcolepsy, a serious sleep disorder in which patients often fall asleep uncontrollably, has been incurable because no effective therapeutic agents are available to date. Recent findings by Japanese scientists in the sleep institute may shed light on this challenging problem.

30 May 2017

Kyoto University researchers identify specific gene as key regulator in iron uptake

Maintaining a good balance of iron in the body is necessary for health: too little can lead to anemia, but too much can cause debilitating disorders such as hemochromatosis.

30 May 2017

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Every animal starts as a clump of cells, which over time multiply and mature into many different types of cells, tissues, and organs.

26 May 2017

Scientists discover receptor protein that promotes chronic heart failure

Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure.

26 May 2017

Innate genetic advantage contributes to better outcomes in newborn infant girls than boys, research shows

Newborn infant girls have better outcomes than their male counterparts due to an innate genetic advantage in responding to acute infections, according to new research from RCSI.

26 May 2017

Trial shows promising results for new medicine in treating severe asthma patients

A trial led by a McMaster University respirology professor shows promising results for a new medicine for severe asthma patients.

25 May 2017

NCCN ORP funds researchers to evaluate targeted treatment in EGFRm+ non-small cell lung cancer

The National Comprehensive Cancer Network Oncology Research Program has funded two investigators from NCCN Member Institutions through a collaborative scientific research relationship with AstraZeneca to further evaluate the clinical effectiveness of osimertinib in the treatment of epidermal growth factor receptor-positive (EGFRm+) non-small cell lung cancer (NSCLC).

25 May 2017

Researchers capture first cryo-EM snapshots of key cellular receptor in action

Researchers at the University of Michigan, Stanford University and biotech company ConfometRx have captured the first cryo-electron microscopy snapshots of a key cellular receptor in action.

25 May 2017

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like severe allergic reactions, acute-onset diabetes and heart damage.

23 May 2017

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Research uncovers role of gut microbiota in anti-obesity effects of dietary capsaicin

Scientists have discovered a dietary strategy that may address obesity by reducing endotoxemia, a major contributor to chronic, low-grade inflammation (CLGI).

23 May 2017

Study describes novel T cell population that recognizes and kills tumor cells

Scientists at the University of Basel in Switzerland have, for the first time, described a new T cell population that can recognize and kill tumor cells. The open access journal eLife has published the results.

23 May 2017

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Drinking just one glass of wine or other alcoholic drink a day increases breast cancer risk, finds a major new report by the American Institute for Cancer Research and the World Cancer Research Fund.

23 May 2017

Investigational biologic may reduce need for systemic corticosteroids in patients with severe asthma

An investigational biologic may reduce the need for adults with severe asthma to take an oral corticosteroid to control their asthma, according to a randomized controlled trial presented at the ATS 2017 International Conference.

22 May 2017

Complex malaria vaccine protects monkeys against virulent parasite strains

Researchers from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite.

22 May 2017

Receptor News and Research

Therapeutic small molecules safely prevent blood clots without excessive bleeding

Brain changes after stroke may lead to increased preference for alcohol, research suggests

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Scientists could be one step closer to developing vaccines against viruses

New study reveals how brain's opioids modulate responses towards other people's pain

Research findings may pave way for miracle drug to treat narcolepsy

Kyoto University researchers identify specific gene as key regulator in iron uptake

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Scientists discover receptor protein that promotes chronic heart failure

Innate genetic advantage contributes to better outcomes in newborn infant girls than boys, research shows

Trial shows promising results for new medicine in treating severe asthma patients

NCCN ORP funds researchers to evaluate targeted treatment in EGFRm+ non-small cell lung cancer

Researchers capture first cryo-EM snapshots of key cellular receptor in action

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

Research uncovers role of gut microbiota in anti-obesity effects of dietary capsaicin

Study describes novel T cell population that recognizes and kills tumor cells

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Investigational biologic may reduce need for systemic corticosteroids in patients with severe asthma

Complex malaria vaccine protects monkeys against virulent parasite strains

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