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Antibodies to SARS-CoV-2 disappear within three months

The question is, does this infection confer lasting immunity? A new study published in the journal Clinical Microbiology and Infection in July 2020 appears to show that it does not, with antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disappearing within three months of infection.

15 Jul 2020

Study: Amount of SARS-Cov-2 receptor is increased in patients with pre-existing cardiac conditions

Nearly 20% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community.

15 Jul 2020

Mobility and flexibility in SARS-CoV-2 proteins

Now, a new study published on the preprint server bioRxiv in July 2020 describes the use of in silico modeling of potential drug targets on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein structures, using data retrieved from the Protein Databank (PDB).

15 Jul 2020

Cold sensitivity of SARS-CoV-2 could impact vaccine studies

Researchers at Duke University in Durham, USA, have made an important discovery about the spike protein on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could have a broad impact on vaccine studies.

14 Jul 2020

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

In a recent bioRxiv study, an ad hoc multi-institutional research team from the US shows that a novel hormone receptor modulator PT150 has unique and possibly additive antiviral and immunomodulatory effects – highlighting its potential role in the treatment and prophylaxis of coronavirus disease (COVID-19).

14 Jul 2020

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

Researchers in San Diego have conducted a study showing that both smoking and the use of e-cigarettes containing nicotine and flavorings may critically exacerbate inflammation in cases of coronavirus disease 2019 (COVID-19) and significantly worsen clinical outcomes.

14 Jul 2020

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Two new studies led by Renuka Iyer, MD, Section Chief for Gastrointestinal Oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors (NETs) - a rare and hard-to-treat cancer.

14 Jul 2020

Your biology may play a role in feeling insecure about romantic relationships

Imagine tracking your feelings during daily interactions with your romantic partner. What would you learn? That's what approximately 100 heterosexual couples in Montreal did each day for 3 weeks during a study run by researchers from McGill University.

14 Jul 2020

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

Absolute Antibody Ltd., an industry-leading provider of recombinant antibody products and services, today announced a partnership with University of Zurich to offer synthetic nanobodies against the receptor binding domain (RBD) of SARS-CoV-2, the coronavirus that causes COVID-19.

From Absolute Antibody Ltd 14 Jul 2020

A new measles-based COVID-19 vaccine

Now, a new study by researchers from Germany's Paul Ehrlich Institute and published on the preprint server bioRxiv in July 2020 describes a potential vaccine based on the measles vaccine, which elicits both an antibody response and cellular immunity against the virus. This also protects against the measles virus. This could be a significant weapon in the fight against these two threats.

14 Jul 2020

Current assays reflect non-neutralizing antibodies, finds study

Several serologic tests have been developed to help diagnose the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), either currently or in the past. However, all of them are not equally effective.

14 Jul 2020

Researchers stabilize the closed SARS-CoV-2 spike trimer

Now, a new study by researchers at Janssen Vaccines & Prevention BV and Leiden University and published on the preprint server bioRxiv uses cryoEM to reveal the structure of this trimer, in order to support both vaccine development and diagnostic testing based on antibody production.

14 Jul 2020

International research collaboration to investigate the role of immune system in health

An international research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

13 Jul 2020

Altimmune announces positive preclinical results of intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

13 Jul 2020

COVID-19 – researchers sum up the “Tsunami” of information

The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection leading to COVID-19 is a raging pandemic across the world at present. It has infected 13 million and killed 571,000 individuals around the world as of today. The infection was first reported in Wuhan, Hubei Province of China in late December 2019.

13 Jul 2020

Scientists discover common molecular feature found in SARS-CoV-2 neutralizing antibodies

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

13 Jul 2020

Bat research critical to help predict and prevent the next pandemic

The current SARS-CoV-2 pandemic has a likely connection to bats, and the next viral outbreak probably will too, unless scientists can quickly learn more about the thousands of viruses carried by one of the most diverse mammals on the planet.

13 Jul 2020

Serology distinguishes children with MIS-C associated with COVID-19

Researchers in the United States say that measuring antibody titers against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may help to distinguish between multisystem inflammatory syndrome in children (MIS-C) and other clinically similar syndromes.

13 Jul 2020

Study shows safety and effectiveness of PET radiotracer in imaging glioblastomas

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

13 Jul 2020

Drug associated with lower mortality in mechanically ventilated COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

13 Jul 2020

Receptor News and Research

Antibodies to SARS-CoV-2 disappear within three months

Study: Amount of SARS-Cov-2 receptor is increased in patients with pre-existing cardiac conditions

Mobility and flexibility in SARS-CoV-2 proteins

Cold sensitivity of SARS-CoV-2 could impact vaccine studies

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Your biology may play a role in feeling insecure about romantic relationships

Absolute Antibody and University of Zurich partner to offer novel SARS-CoV-2 sybodies

A new measles-based COVID-19 vaccine

Current assays reflect non-neutralizing antibodies, finds study

Researchers stabilize the closed SARS-CoV-2 spike trimer

International research collaboration to investigate the role of immune system in health

Altimmune announces positive preclinical results of intranasal COVID-19 vaccine candidate

COVID-19 – researchers sum up the “Tsunami” of information

Scientists discover common molecular feature found in SARS-CoV-2 neutralizing antibodies

Bat research critical to help predict and prevent the next pandemic

Serology distinguishes children with MIS-C associated with COVID-19

Study shows safety and effectiveness of PET radiotracer in imaging glioblastomas

Drug associated with lower mortality in mechanically ventilated COVID-19 patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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