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People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

A team of researchers from the Nagoya University Graduate School of Medicine has reported that patients with a rare form of brain and spinal cord cancer, localized isocitrate dehydrogenase wild-type (IDHwt) histologically diffuse astrocytoma, have a poor prognosis similar to the most malignant types of brain and spinal cord tumors.

31 Mar 2023

New microfluidic device quickly and automatically predicts the effectiveness of cancer treatment

One of the great challenges in the fight against cancer is to design new technologies for a personalized treatment for each patient.

31 Mar 2023

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Researchers investigated the feasibility of utilizing a bacterial contractile injection system for programmable protein delivery.

31 Mar 2023

Study shows how many HBeAg-negative patients can achieve permanent immune control of hepatitis B

More than half of patients who suffer from chronic hepatitis B have the e antigen (HBeAg)-negative form of the disease.

30 Mar 2023

Music therapy proves effective in treating depression for ADHD in children and adolescents

How music therapy can improve the treatment of depression in children with Attention deficit-hyperactivity disorder (ADHD).

30 Mar 2023

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

Aging, or senescent cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

30 Mar 2023

CAR T-cell therapy improves quality of life for patients with blood cancers

Chimeric antigen receptor T-cell (CAR-T) therapy has transformed cancer treatment, yet relatively few studies have investigated the impact of the therapy on longitudinal patient quality of life – an aspect of care that often suffers from receiving traditional intensive cancer medications, such as chemotherapy.

30 Mar 2023

Study shows how neutrophils play a key role in cancer immunotherapy success

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

30 Mar 2023

Riboswitch may be the key to advance gene therapy, regenerative medicine

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

30 Mar 2023

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

A study published in Cell Reports Medicine describes that COVID-19 vaccines induce strong T cell response in blood cancer patients, irrespective of antibody response and B cell numbers.

30 Mar 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Monthly prophylactic injections of fitusiran are effective in reducing bleeds in patients with hemophilia A or B, according to randomized controlled trials publishing simultaneously in The Lancet and The Lancet Haematology journals.

30 Mar 2023

Anxiety attack or panic attack: Both may have come from the brain

An attack can come crashing in like a storm on a clear spring day. In an instant, your heart pounds, sweat soaks you and you struggle to breathe.

29 Mar 2023

Mapping neural connections in OCD patients can predict improvements after deep brain stimulation

Deep brain stimulation (DBS) is a promising therapy for treatment-resistant obsessive-compulsive disorder (OCD).

29 Mar 2023

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

In recent years, innovative cancer drugs that target specific molecular drivers of the disease have been embraced as the treatment of choice for many types of cancer.

29 Mar 2023

Lab-made antibodies may be able to cure people infected with yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

29 Mar 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

29 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

Therapy News and Research

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

New microfluidic device quickly and automatically predicts the effectiveness of cancer treatment

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Study shows how many HBeAg-negative patients can achieve permanent immune control of hepatitis B

Music therapy proves effective in treating depression for ADHD in children and adolescents

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

CAR T-cell therapy improves quality of life for patients with blood cancers

Study shows how neutrophils play a key role in cancer immunotherapy success

Riboswitch may be the key to advance gene therapy, regenerative medicine

The breadth of immune responses following COVID-19 vaccination in hematology patients with diseases and treatments impacting B cell immunity

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Anxiety attack or panic attack: Both may have come from the brain

Mapping neural connections in OCD patients can predict improvements after deep brain stimulation

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Synthetic hydrogel-based lymphoma tumor model paves way for personalized cancer therapies

Lab-made antibodies may be able to cure people infected with yellow fever

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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