Depressive Disorder News and Research

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Blood test to diagnose depression in adolescents

Researchers have developed a blood test that can diagnose depression in teens, a step they hope will lead to a better way to identify the disorder in young people. At present diagnosing depression depends entirely on a patient's willingness to report symptoms. For teens, the diagnosis is particularly challenging, given the natural emotional ups and downs of adolescence.

18 Apr 2012

Study supports tolerability of low-dose aripiprazole as an antidepressant therapy-augmenting agent

In the current issue of Psychotherapy and Psychosomatics there is a negative study on the use of aripiprazole in depression.

18 Apr 2012

Ameritox, Ridge Diagnostics partner to develop MDDScore test

Ridge Diagnostics, Inc., a neurodiagnostic company, announced today it has entered into an exclusive agreement with Ameritox, Ltd., a leader in medication monitoring, for the license rights to its proprietary developmental blood test MDDScore, a multiple biomarker analysis for Major Depressive Disorder (MDD) for primary care and pain physicians.

6 Apr 2012

African-Americans and Hispanics with MDD less likely to get antidepressants

African-Americans and Hispanics with major depressive disorder are less likely to get antidepressants than Caucasian patients, and Medicare and Medicaid patients are less likely to get the newest generation of antidepressants.

6 Apr 2012

Regulatory agencies approve plans for e-Therapeutics' ETS2101 phase I trials in cancer

e-Therapeutics plc announces that regulatory agencies in the UK and the US have approved plans for phase I trials of the Company's anti-cancer drug ETS2101 and that enrolment of patients into trials in these two countries will begin shortly.

29 Mar 2012

Simple placebo pill can track footprints of prior antidepressant use

Individuals with major depressive disorder (MDD) often undergo multiple courses of antidepressant treatment during their lives. This is because the disorder can recur despite treatment and because finding the right medication for a specific individual can take time.

27 Mar 2012

AstraZeneca, Targacept announce top-line results from remaining TC-5214 Phase 3 studies on MDD

AstraZeneca and Targacept, Inc. today announced top-line results from the remaining Phase 3 studies investigating efficacy, tolerability and safety of TC-5214 as an adjunct therapy to an antidepressant in patients with major depressive disorder (MDD) who did not respond adequately to initial antidepressant treatment.

20 Mar 2012

Longer looks: Romney's evolution on abortion; The birth of the HIV epidemic

GOP presidential candidate Mitt Romney began his political career as a pro-choicer. In the story he tells, he had an epiphany, a flash of insight, and committed himself thereafter to protecting life. But that isn't what happened. The real story of Romney's conversion - a series of tentative, equivocal, and confused shifts, accompanied by a constant rewriting of his past - paints a more accurate picture of who he is.

2 Mar 2012

Gedeon Richter and Forest Labs' cariprazine Phase III trials on schizophrenia meet primary endpoint

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive top-line results in 2 Phase III clinical trials of cariprazine (RGH-188) for the treatment of acute exacerbation of schizophrenia.

28 Feb 2012

People with depression have increased connections among most brain areas

Most of us know what it means when it's said that someone is depressed. But commonly, true clinical depression brings with it a number of other symptoms. These can include anxiety, poor attention and concentration, memory issues, and sleep disturbances.

27 Feb 2012

Telomeres - the indicators of aging - are highly susceptible to stress and depression

Stress has numerous detrimental effects on the human body. Many of these effects are acutely felt by the sufferer, but many more go 'unseen', one of which is shortening of telomere length.

22 Feb 2012

Internet addiction, shyness, defiance and grief on bereavement could be mental disorders – Debate on proposed DSM-5

The American Psychiatric Association (APA) has attracted a lot of debate on its proposed amendments to its newest Diagnostic and Statistical Manual of Mental Disorders (DSM) the outlines psychiatric symptoms in the mental-health industry.

13 Feb 2012

Assay analyzing multiple biomarkers could be valuable aid to diagnose major depression

The initial assessment of a blood test to help diagnose major depressive disorder indicates it may become a useful clinical tool. In a paper published in the journal Molecular Psychiatry, a team including Massachusetts General Hospital (MGH) researchers reports that a test analyzing levels of nine biomarkers accurately distinguished patients diagnosed with depression from control participants without significant false-positive results.

2 Feb 2012

Study finds no link between BDV and psychiatric illness

Over the past 30 years, numerous studies have linked Borna disease virus (BDV) with mental illnesses such as bipolar disorder, schizophrenia, anxiety disorder and dementia. Genetic fragments and antibodies to this RNA virus, which causes behavior disorders in a range of mammals and birds, have been found to be prevalent in psychiatric patients, but study results have been inconsistent. Now, the first blinded, case-control study to examine this issue finds no association between the virus and psychiatric illness.

1 Feb 2012

Exercise training can combat depressive symptoms in patients with chronic illness

Combat feelings of sadness that often accompany chronic illness with a good work-out, say University of Alabama at Birmingham researchers in a study published recently in the Archives of Internal Medicine.

1 Feb 2012

States redesigning mental health programs, coverage and care

States are grappling with mental health issues including a redesign of a program in Iowa, increased coverage for the mentally ill in California and a mental health first aid pilot program in Pennsylvania.

30 Jan 2012

Potential role of omega-3 fatty acid in preventing psychological consequences of accidents

A report in the 5th 2011 issue of Psychotherapy and Psychosomatics suggests the potential role of omega-3 fatty acid in preventing the psychological consequences of an accident.

23 Jan 2012

Low levels of vitamin D may increase risk of depression

Low levels of vitamin D have been linked to depression, according to UT Southwestern Medical Center psychiatrists working with the Cooper Center Longitudinal Study. It is believed to be the largest such investigation ever undertaken.

5 Jan 2012

Positive results from Alkermes ALKS 5461 phase 1/2 study on MDD

Alkermes plc today announced positive topline results from a phase 1/2 study of ALKS 5461, a novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression.