Gastrointestinal Tract News and Research

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Women with PCOS likely to have less diverse gut bacteria, study reveals

Women who have a common hormone condition that contributes to infertility and metabolic problems tend to have less diverse gut bacteria than women who do not have the condition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

23 Jan 2018

Gastric environment permanently changes in the presence of Helicobacter pylori infection

The make-up of the human gut flora is highly individual and extremely diverse. However, when a Helicobacter pylori infection is present, this bacterium displaces all other bacteria in the gastrointestinal tract, leaving only Helicobacter bacteria in the stomach.

23 Jan 2018

Powerful anti-oxidant can stop progression of fatty liver disease in young mice

As obesity continues to rise in the U.S., non-alcoholic fatty liver disease (NAFLD) has become a major public health issue, increasingly leading to cancer and liver transplants.

22 Jan 2018

Bacteria linked to periodontitis may play role in onset of cancer

The bacteria that cause periodontitis, a disease affecting the tissues surrounding the teeth, seems to play a part also in the onset of pancreatic cancer, say the researchers at the University of Helsinki and the Helsinki University Hospital, Finland, and the Karolinska Institutet, Sweden.

16 Jan 2018

FAU researchers show that fiber-rich diet has positive effect on inflammatory joint diseases

It is well known that healthy eating increases our general sense of wellbeing. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have now discovered that a fiber-rich diet can have a positive influence on chronic inflammatory joint diseases, leading to stronger bones.

12 Jan 2018

Researchers discover new type of botulinum neurotoxin from unexpected source

Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut.

12 Jan 2018

Gene therapy with CAR T-cells could create long-term immunity from HIV

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells.

29 Dec 2017

Research explores benefits of gut health from several angles

Gut health is a key area of modern health research, with intensive examination of communication between our gut and our brain deemed pivotal to solving complex health and wellbeing issues.

21 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

UMSOM researchers find two-way link between TBI and intestinal changes

University of Maryland School of Medicine researchers have found a two-way link between traumatic brain injury (TBI) and intestinal changes. These interactions may contribute to increased infections in these patients, and may also worsen chronic brain damage.

7 Dec 2017

UAH study investigates effects of hot yoga on bone mineral density

Bikram yoga, the most commonly practiced type of hot yoga, offers practitioners a vigorous workout in a studio kept at 100°F or more.

28 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

Tulane professor wins Department of Defense grant for research into arteriovenous malformations

Tulane University's Stryder Meadows, a cell and molecular biology professor, received a $1.7 million grant from the Department of Defense to study how arteriovenous malformations (AVM), which are defects in arteries, veins and capillaries, form Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder that affects about 1 in 5,000 people.

14 Nov 2017

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

The Center for Applied NanoBioscience and Medicine is doing its part to protect the health of astronauts on long-duration missions, including NASA's Journey to Mars.

9 Nov 2017

Overabundance of gut bacteria may exacerbate pain in patients with sickle cell disease

An overabundance of the bacteria Veillonella in the digestive tract may increase pain in patients with sickle cell disease (SCD).

8 Nov 2017

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.

8 Nov 2017

Low-energy ESWT shows promise for managing digital ulcers in patients with systemic sclerosis

Extracorporeal shock-wave therapy at low energy levels showed promise as a new treatment for digital ulcers in patients with systemic sclerosis, or scleroderma, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Study points to novel, effective treatment for CKD patients with metabolic acidosis

Patients with chronic kidney disease (CKD) often develop a condition called metabolic acidosis, which is characterized by an imbalance in acid production relative to excretion.

6 Nov 2017

Nicotine alters gut microbiome differently in males and females, mice study shows

Many people who smoke or chew tobacco can't seem to escape nicotine's addictive properties. Studies show that women in particular seem to have a harder time quitting, even with assistance, when compared to men.

3 Nov 2017

Research may explain why gum disease is linked to heart problems

Heart disease and fatty clogs in the arteries go hand in hand. But new evidence suggests the fatty molecules might come not only from what you eat, but from the bacteria in your mouth, report UConn scientists in the 16 August issue of the Journal of Lipid Research.

1 Nov 2017