Malignant News and Research

RSS

Deep visual proteomics is redefining cancer diagnostics

In a recent study published in the journal Nature Biotechnology, researchers introduced deep visual proteomics (DVP), an amalgamation of artificial intelligence (AI) for image analysis and mass spectrometry (MS) for proteomic profiling of biological samples.

22 May 2022

Small cell lung cancer subtypes respond differently to chemotherapeutics and targeted drugs

Small cell lung cancer (SCLC) is a malignant disease associated with a particularly high mortality rate. According to a new multicenter study led by MedUni Vienna and conducted in collaboration with researchers from the Czech Republic, Hungary, Slovenia, Sweden and the United States, SCLC can be divided into several subgroups in terms of clinical behavior.

17 May 2022

CDC reports increase in mesothelioma deaths among women

In a recent study published in the CDC’s Morbidity and Mortality Weekly Report, researchers analyzed the incidence of malignant mesothelioma mortality in females in the US.

17 May 2022

Prostate cancer patients benefit from precision oncology

Researchers at the University of Bern and University Hospital Bern have achieved a breakthrough in a particularly aggressive form of prostate cancer.

11 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease with high accuracy by evaluating histological images.

10 May 2022

Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children.

9 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

What can chimpanzees tell us about cancer propensity in humans?

A recent study published in the renowned journal Cell Reports finds evidence for reduced functional activity of certain human cancer genes (such as breast cancer 2 gene or BRCA2), following the divergence from the chimpanzee-human last common ancestor.

9 May 2022

The Josep Carreras Leukaemia Research Institute joins Cancer Proteome Project

The Josep Carreras Institute becomes part of the Cancer Proteome project, an international initiative for the study of malignant tumors.

6 May 2022

Antigen-presenting cancer-associated fibroblasts offer a new target to fight pancreatic cancer

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests.

6 May 2022

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Researchers have developed a method to accurately detect viruses from clinical next-generation sequencing and describe novel associations between specific tumors and viruses that warrant further investigation.

5 May 2022

Low-cost handheld device could cut the rate of unnecessary skin biopsies

Skin biopsies are no fun: doctors carve away small lumps of tissue for laboratory testing, leaving patients with painful wounds that can take weeks to heal.

5 May 2022

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

In a new study, researchers assessed the efficacy of a third dose of COVID-19 vaccine in anti-CD20 antibody-treated individuals.

4 May 2022

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Glioma is an intracranial malignant tumor that still poses a major clinical challenge due to its highly invasive nature, low cure rate, and high mortality rate.

3 May 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Massachusetts General Hospital researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

28 Apr 2022

Malignant News and Research

Deep visual proteomics is redefining cancer diagnostics

Small cell lung cancer subtypes respond differently to chemotherapeutics and targeted drugs

CDC reports increase in mesothelioma deaths among women

Prostate cancer patients benefit from precision oncology

Tumors release lactate to force neighboring cells into supporting cancer growth

AI model predicts postoperative recurrence of Crohn disease with high accuracy

Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

T cell behavior informs metastatic melanoma outcomes

What can chimpanzees tell us about cancer propensity in humans?

The Josep Carreras Leukaemia Research Institute joins Cancer Proteome Project

Antigen-presenting cancer-associated fibroblasts offer a new target to fight pancreatic cancer

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Low-cost handheld device could cut the rate of unnecessary skin biopsies

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

Blood test could aid in the differential diagnosis of preeclampsia and COVID-19 in pregnant women

Researchers reveal how not-yet-malignant cells “turn on” and become metastatic breast cancer

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News