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Research findings provide new conceptual framework for understanding brain inflammation after injury

Researchers have identified a new mechanism by which inflammation can spread throughout the brain after injury. This mechanism may explain the widespread and long-lasting inflammation that occurs after traumatic brain injury, and may play a role in other neurodegenerative diseases.

8 Mar 2017

Sex differences in microglia activity affect pain treatment, study finds

A female brain's resident immune cells are more active in regions involved in pain processing relative to males, according to a recent study by Georgia State University researchers.

2 Mar 2017

BUSM researchers participate in five-year program to develop biomarkers for small vessel disease

To better predict, study and diagnose small vessel disease in the brain and its role in vascular contributions to cognitive impairment and dementia (VCID), Boston University School of Medicine has been selected to participate in MarkVCID, a consortium designed to accelerate the development of new and existing biomarkers for small vessel VCID.

2 Mar 2017

Salk Institute researchers reveal how to curb immune enthusiasm

Normally when we think of viruses, from the common cold to HIV, we want to boost people's immunity to fight them.

20 Jan 2017

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients

18 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Antibiotics targeting brain’s inflammatory response may exacerbate cognitive deficits in children

Traumatic brain injury (TBI) is one of the leading causes of disability and death in infants and children in the United States, with more than half a million affected annually, according to the Centers for Disease Control and Prevention.

11 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease.

21 Dec 2016

Scientists discover incident commander in the brain that defends against invading virus

Imagine seeing a building on fire. You grab the phone and call the fire service. What happens next can be compared to the discovery made by researchers from Aarhus University.

8 Dec 2016

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Autism spectrum disorder is caused by a variety of factors, both genetic and environmental.

5 Dec 2016

Exposure to allergens during pregnancy alters the brain makeup of fetuses and newborn rats

A new study in rats could begin to explain why allergies during pregnancy are linked to higher risks for attention-deficit hyperactivity disorder and autism in children.

17 Nov 2016

Research shows CRAC channel inhibitors decrease lesion size, brain hemorrhage, and neurological deficits in TBI model

Researchers from the San Francisco Veterans Affairs Medical Center and UCSF, and CalciMedica, Inc., are presenting a poster at the 46th annual Society for Neuroscience meeting in San Diego describing the use of calcium release-activated calcium (CRAC) channel inhibitors in traumatic brain injury (TBI).

16 Nov 2016

New research uncovers role of spleen in long-term anxiety following psychological stress

Scientists are uncovering clues to what might be unfolding in the relationship between the brain and immune system in those who suffer from long-term repercussions of stress.

14 Nov 2016

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

An experimental drug shows promise in treating Alzheimer's disease by preventing inflammation and removing abnormal protein clumps in the brain that are associated with the disease, suggests a study in mice presented at the ANESTHESIOLOGY 2016 annual meeting.

25 Oct 2016

Oligodendrocytes selectively myelinate specific set of neuronal axons, research shows

There are three kinds of glial cells in the brain, oligodendrocyte, astrocyte and microglia. Oligodendrocytes myelinate neuronal axons to increase conduction velocity of neuronal impulses.

21 Oct 2016

NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

Microglia are cells that combat various brain diseases and injuries by swallowing foreign or disruptive objects and releasing molecules that activate repair mechanisms.

26 Aug 2016

Neuropathic pain could be significantly reduced by targeting brain cells

Neuropathic pain - which affects more than 1 million Americans - could be reduced or even eliminated by targeting brain cells that are supposed to provide immunity but, in some instances, do the opposite, causing chronic pain that could last a lifetime.

8 Aug 2016

Seasonal allergies may alter the brain, study shows

Hay fever may do more than give you a stuffy nose and itchy eyes, seasonal allergies may change the brain, says a study published in the open-access journal Frontiers in Cellular Neuroscience.

8 Aug 2016

Novel therapeutic strategy could target multiple aspects of Alzheimer's disease

Therapeutic strategies targeting Alzheimer's disease (AD)-related molecule β-amyloid (Aβ), Tau protein and BACE enzyme have been recently explored. However the therapeutic efficacy for a single target is not ideal.

8 Aug 2016

Microglia News and Research

Research findings provide new conceptual framework for understanding brain inflammation after injury

Sex differences in microglia activity affect pain treatment, study finds

BUSM researchers participate in five-year program to develop biomarkers for small vessel disease

Salk Institute researchers reveal how to curb immune enthusiasm

Researchers identify brain cell types from cell culture of adult human neurons

Could pathogen infection really lead to Alzheimer’s?

Antibiotics targeting brain’s inflammatory response may exacerbate cognitive deficits in children

How does the brain control appetite?

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists discover incident commander in the brain that defends against invading virus

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Exposure to allergens during pregnancy alters the brain makeup of fetuses and newborn rats

Research shows CRAC channel inhibitors decrease lesion size, brain hemorrhage, and neurological deficits in TBI model

New research uncovers role of spleen in long-term anxiety following psychological stress

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

Oligodendrocytes selectively myelinate specific set of neuronal axons, research shows

NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

Neuropathic pain could be significantly reduced by targeting brain cells

Seasonal allergies may alter the brain, study shows

Novel therapeutic strategy could target multiple aspects of Alzheimer's disease

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