Musculoskeletal News and Research

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Repurposing an anti-inflammatory drug can prevent lung disease in patients with systemic sclerosis

Research led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab, a FDA-approved anti-inflammatory drug used to combat rheumatoid arthritis, can prevent lung disease in patients with systemic sclerosis if detected early enough in the disease course.

31 Mar 2021

Scientists use specially designed gold nanoparticles to 'seek out' bone stem cells

Researchers at the University of Southampton have developed a new way of using nanomaterials to identify and enrich skeletal stem cells - a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone.

29 Mar 2021

GBP5 protein may play a key role in suppressing inflammation in rheumatoid arthritis

New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune system mistakenly attacks the body's own joint tissues.

29 Mar 2021

First cell-based gene therapy approved by the FDA for treating multiple myeloma

The U.S. Food and Drug Administration approved Abecma (idecabtagene vicleucel), a cell-based gene therapy to treat adult patients with multiple myeloma who have not responded to, or whose disease has returned after, at least four prior lines (different types) of therapy.

29 Mar 2021

New study shows large within- and between-assay variation for ß-CTX measurement

A new study by the IFCC‑IOF Committee for Bone Metabolism shows large within- and between-assay variation for ß-CTX measurement; until harmonization is achieved, proposes measuring ß-CTX by the same assay on EDTA plasma, especially for research.

25 Mar 2021

Study shows cost-effectiveness of total knee replacement for patients with knee osteoarthritis

Knee osteoarthritis is a painful condition that affects over 14 million U.S. adults, many of whom have extreme obesity, defined by body mass index (BMI) greater than 40kg/m2.

23 Mar 2021

Under new cost-cutting Medicare rule, same surgery, same place, different bill

A cost-saving change in Medicare launched in the final days of the Trump administration will cut payments to hospitals for some surgical procedures while potentially raising costs and confusion for patients.

23 Mar 2021

Chemical cocktail shows promise for producing muscle stem cells

A UCLA-led research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells.

19 Mar 2021

$Hospital charges increasing more rapidly for hip fracture patients than surgeon reimbursements$

Hospital charges increasing more rapidly for hip fracture patients than surgeon reimbursements

In recent years, hospital charges and Medicare payments for patients with hip fractures have increased much more rapidly than charges and payments for orthopaedic surgeons, reports a study in the Journal of Orthopaedic Trauma.

17 Mar 2021

Multiyear workplace health promotion program can reduce health risks for working-age people

A multiyear workplace health promotion program can slow down the increase in health risks for working-age people.

13 Mar 2021

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders.

11 Mar 2021

Tiny antibodies naturally generated by llamas can be effective against COVID-19

As the fight against COVID-19 continues, scientists have turned to an unlikely source for a potentially effective treatment: tiny antibodies naturally generated by llamas.

10 Mar 2021

Multisystem intervention could potentially prevent or reverse frailty, research shows

Physicians understand frailty as a dysregulation among multiple systems in the body that make it less resilient and unable to recover completely when faced with a physical challenge such as injury or illness.

8 Mar 2021

Micro-Doppler radars could soon be used to predict injury risk and track recovery

Micro-Doppler radars could soon be used in clinical settings to predict injury risk and track recovery progress, according to Penn State researchers.

4 Mar 2021

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Tissue engineering has long-depended on geometrically static scaffolds seeded with cells in the lab to create new tissues and even organs.

2 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

Learning to live again: A Lazarus tale from the Covid front lines

The twinkle in his eyes, the delight in his smile, the joyous way he moved his disease-withered frame. They all proclaimed a single, resounding message: Grateful to be alive!

26 Feb 2021

New hydrogel-based materials show promise for tissue engineering

New hydrogel-based materials that can change shape in response to psychological stimuli, such as water, could be the next generation of materials used to bioengineer tissues and organs, according to a team of researchers at the University of Illinois Chicago.

25 Feb 2021

Kessler team receives funding to study factors leading to osteoarthritis after knee injury

Gerard Malanga, MD, and Nathan Hogaboom, PhD, of Kessler Foundation received a $185,707 award from The Geneva Foundation (Geneva) to study factors contributing to the development of osteoarthritis following acute knee injuries, a common disabling condition among active-duty military personnel.

22 Feb 2021

Early immunosuppressive biomarkers could predict bone regeneration after trauma

An abnormal suppression of the immune system linked to the onset of numerous diseases has been associated with poor functional regeneration of traumatic bone injuries.

18 Feb 2021

Musculoskeletal News and Research

Repurposing an anti-inflammatory drug can prevent lung disease in patients with systemic sclerosis

Scientists use specially designed gold nanoparticles to 'seek out' bone stem cells

GBP5 protein may play a key role in suppressing inflammation in rheumatoid arthritis

First cell-based gene therapy approved by the FDA for treating multiple myeloma

New study shows large within- and between-assay variation for ß-CTX measurement

Study shows cost-effectiveness of total knee replacement for patients with knee osteoarthritis

Under new cost-cutting Medicare rule, same surgery, same place, different bill

Chemical cocktail shows promise for producing muscle stem cells

Hospital charges increasing more rapidly for hip fracture patients than surgeon reimbursements

Multiyear workplace health promotion program can reduce health risks for working-age people

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Tiny antibodies naturally generated by llamas can be effective against COVID-19

Multisystem intervention could potentially prevent or reverse frailty, research shows

Micro-Doppler radars could soon be used to predict injury risk and track recovery

New 4D hydrogels may help develop tissues that closely resemble their natural counterparts

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

Learning to live again: A Lazarus tale from the Covid front lines

New hydrogel-based materials show promise for tissue engineering

Kessler team receives funding to study factors leading to osteoarthritis after knee injury

Early immunosuppressive biomarkers could predict bone regeneration after trauma

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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