Ovaries News and Research

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Screening unhelpful in lowering deaths from ovarian cancer

New research shows that women regularly screened for ovarian cancer are just as likely to die from the disease. This comes as no surprise as there are still no adequate detection methods, says Ovarian Cancer Australia. Of the 1,200 Australian women diagnosed with ovarian cancer each year, 800 die, often because it is diagnosed too late to be treated.

5 Jun 2011

HRT reduces risk of breast cancer in women with BRCA mutations after ovary removal

Women with the BRCA1 or BRCA2 gene mutations, which are linked to a very high risk of breast and ovarian cancer, can safely take hormone-replacement therapy (HRT) to mitigate menopausal symptoms after surgical removal of their ovaries, according to new research from the Perelman School of Medicine at the University of Pennsylvania which will be presented Monday, June 6 during the American Society for Clinical Oncology's annual meeting.

4 Jun 2011

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

5% to 10% of all breast cancers are monogenic in origin. In other words, there is a mutation of the genes BRCA1, BRCA2 or other high-risk genes. In this edition of Deutsches Ärzteblatt International, Alfons Meindl of the Klinikum rechts der Isar and coauthors report on new insights into the pathogenesis and treatment of hereditary breast and ovarian cancer and newly-discovered risk genes.

30 May 2011

Caffeine reduces muscle activity in Fallopian tubes

Caffeine reduces muscle activity in the Fallopian tubes that carry eggs from a woman's ovaries to her womb. "Our experiments were conducted in mice, but this finding goes a long way towards explaining why drinking caffeinated drinks can reduce a woman's chance of becoming pregnant," says Professor Sean Ward from the University of Nevada School of Medicine, Reno, USA. Ward's study is published today in the British Journal of Pharmacology

24 May 2011

Study finds strong link between live birth rates and number of eggs retrieved in one IVF cycle

An analysis of over 400,000 IVF cycles in the UK has shown that doctors should aim to retrieve around 15 eggs from a woman's ovaries in a single cycle in order to have the best chance of achieving a live birth after assisted reproduction technology.

11 May 2011

Treatment with estrogen-lowering drugs shrinks tumors and reduces mastectomy rates in breast cancer patients

In the first large trial of its kind in the United States, researchers have shown that estrogen-lowering drugs can shrink tumors and reduce mastectomy rates for patients with stage 2 or 3 breast cancer.

10 May 2011

Study finds more evidence linking high-grade serous ovarian cancer to fallopian tubes

High-grade serous ovarian cancer (HGSOC), the fifth-deadliest cancer among American women, is thought by many scientists to often be a fallopian tube malignancy masquerading as an ovarian one. While most of the evidence linking HGSOC to the fallopian tubes has so far been only circumstantial, a new Dana-Farber Cancer Institute study suggests there is a direct connection, a finding that could aid in the development of better treatments for the cancer.

19 Apr 2011

Organic pollutants in flame retardents cause molecular changes in reproductive organs

Polybrominated diphenyl ethers (PBDEs) are chemicals that have been widely used as flame retardants and are now classified as persistent organic pollutants. Health concerns in humans have arisen based primarily on studies with laboratory animals exposed to high levels of PBDEs. Three commercial mixtures of PBDEs have been manufactured in or imported into the United States which include penta-, octa-, and deca-brominated diphenyl ethers (BDEs).

15 Apr 2011

New treatment approach raises hope for women with ovarian cancer

Researchers at Oregon Health & Science University's Oregon National Primate Research Center may have good news for women at high-risk for ovarian cancer who also want to have children.

8 Apr 2011

Study shows immune therapy can prevent pregnancy in mammals including humans

Researchers at Weill Cornell Medical College have shown that it is possible to immunize mammals to control fertility. They say their technique could possibly be used on other mammals -- including humans -- because fertility hormones and their receptors are species-non-specific and are similar in both females and males.

1 Apr 2011

Immune therapy can control fertility in mammals

31 Mar 2011

EMA CHMP adopts positive opinion for Teva's NOMAC-E2 contraceptive pill

Teva Pharmaceutical Industries Ltd. today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion for NOMAC-E2, an investigational contraceptive pill combining 1.5 mg of 17-beta-estradiol with 2.5 mg of nomegestrol acetate in a 24/4 monophasic regimen.

18 Mar 2011

MabCure presents ovarian cancer diagnostic blood test study results at SGO meeting

Biotechnology company MabCure, Inc. is presenting the results of its recently completed study on the diagnosis of ovarian cancer utilizing its proprietary monoclonal antibodies at the annual meeting of the Society of Gynecological Oncologists.

9 Mar 2011

Pretreatment with FDA-approved drug allows successful pregnancies in radiation-exposed rhesus monkeys

A strategy developed by Massachusetts General Hospital (MGH) researchers to shield the ovaries of female mammals from the damaging effects of radiation and chemotherapy has passed an important milestone. A collaborative study with investigators from Oregon Health and Sciences University (OHSU), published online in the journal Fertility and Sterility, reports that brief preexposure of the ovaries to an FDA-approved agent called FTY720 preserved the fertility of female rhesus monkeys exposed to potentially lethal doses of radiation.

23 Feb 2011

Skeleton regulates fertility in males, but not females

Researchers at Columbia University Medical Center have discovered that the skeleton acts as a regulator of fertility in male mice through a hormone released by bone, known as osteocalcin.

17 Feb 2011

Potential biomarkers for early diagnosis of ectopic pregnancy

A long, urgent search for proteins in the blood of pregnant women that could be used in early diagnosis of ectopic pregnancy (EP) has resulted in discovery of biomarkers that seem to be specific enough to begin testing in clinical trials, scientists are reporting in a new study in ACS's Journal of Proteome Research.

17 Feb 2011

Acupuncture and exercise help women with PCOS

Acupuncture and physical exercise improve hormone levels and menstrual bleeding pattern in women with polycystic ovary syndrome (PCOS), reveals research from the University of Gothenburg, Sweden.

7 Feb 2011

Antioxidants may cause fertility problems in females

Antioxidants are sold over the counter everywhere. They're added to food, drink and face cream. But according to Prof. Nava Dekel of the Biological Regulation Department, we still don't have a complete understanding of how they act in our bodies. New research by Dekel and her team, recently published in the Proceedings of the National Academy of Sciences USA (PNAS), has revealed a possible unexpected side effect of antioxidants: They might cause fertility problems in females.

19 Jan 2011

Gene changes during brain development can lead to male genitalia formation in female embryo

Australian scientists have discovered that changes to a gene involved in brain development can lead to testis formation and male genitalia in an otherwise female embryo.

22 Dec 2010

Ultrasound-based diagnosis for rapid detection of benign and malignant ovarian cancer

It is crucial to differentiate between benign and malignant ovarian cysts and tumours in a fast and reliable manner. This improves the surgical management and prognosis of the patient.

16 Dec 2010