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Analytical strategies that support OSD formulation: A new whitepaper from Malvern Instruments

A new whitepaper from Malvern Panalytical provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.

From Malvern Panalytical 12 Feb 2015

SRI Biosciences awarded contract to develop novel polymers to neutralize chemical, biological threats

SRI Biosciences, a division of SRI International, has been awarded a $10 million contract under a DARPA program to reimagine how proteins are constructed and to develop novel medicines and diagnostics as countermeasures to chemical and biological threats.

12 Feb 2015

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it's very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.

5 Feb 2015

Comb-shaped polymers efficiently protect proteins in vivo

An enzyme that usually triggers strong allergic reactions now circulates in the veins of a group of mice without alerting the immune system. As INRS Énergie Matériaux Télécommunications Research Centre Professor Marc A. Gauthier explains in an article published in the journal Nature Communications, a polymer was used to camouflage the enzyme before it was injected into the rodents. This was achieved by coating the enzyme to avoid an immune response in a manner that does not compromise its activity.

6 Dec 2014

Researchers figure out how to reverse characteristics of polyurea materials

Researchers at the University of Illinois at Urbana-Champaign have figured out how to reverse the characteristics of a key bonding material--polyurea--providing an inexpensive alternative for a broad number of applications, such as drug delivery, tissue engineering, and packaging.

5 Dec 2014

Load bearing, biodegradable implants can reduce the number of second surgeries

No other joint in the human body is as highly mobile as is the shoulder. However, it is also very sensitive and prone to injury, with athletes being particularly affected.

14 Nov 2014

PGI net sales increase 72.3% to $498.0 million in third quarter 2014

Polymer Group, Inc. reported results of operations for the third quarter ended September 27, 2014.

12 Nov 2014

Salivary mucins protect teeth from cariogenic bacterium

Salivary mucins, key components of mucus, actively protect the teeth from the cariogenic bacterium, Streptococcus mutans, according to research published ahead of print in Applied and Environmental Microbiology. The research suggests that bolstering native defenses might be a better way to fight dental caries than relying on exogenous materials, such as sealants and fluoride treatment, says first author Erica Shapiro Frenkel, of Harvard University, Cambridge, MA.

11 Nov 2014

Acino recognized with 2014 Europe Frost & Sullivan Award for Enabling Technology Leadership

Based on its recent analysis of the pharmaceutical drug delivery industry, Frost & Sullivan recognizes Acino Pharma AG with the 2014 Europe Frost & Sullivan Award for Enabling Technology Leadership. Acino's expertise in targeted drug release profiles and strong technical know-how in pellet-coating, transdermal therapeutic patches and biodegradable implants has made it the preferred vendor in contract manufacturing.

6 Nov 2014

UT Arlington professor uses tissue-engineered artificial lymph nodes to draw prostate cancer cells

A UT Arlington bioengineering professor is using tissue-engineered artificial lymph nodes to attract prostate cancer cells to better target and eradicate the disease.

5 Nov 2014

Dietary flavonoids decrease risk of developing epithelial ovarian cancer

Tea and citrus fruits and juices are associated with a lower risk of developing ovarian cancer, according to new research from the University of East Anglia.

28 Oct 2014

UMass Amherst cell biologists propose new detailed cytokinesis model

Along with copying and splitting DNA during division, cells must have a way to break safely into two viable daughter cells, a process called cytokinesis. But the molecular basis of how plant cells accomplish this without mistakes has been unclear for many years.

26 Sep 2014

TSRI scientists awarded DARPA grant to build artificial immune system

Scientists from both campuses of The Scripps Research Institute have been awarded a total of $7.9 million from the Defense Advanced Research Projects Agency of the U.S. Department of Defense.

25 Sep 2014

Case Western Reserve University’s synchrotron facility to become No. 1 beamline facility for biology

Case Western Reserve University’s synchrotron facility at Brookhaven National Laboratory is on its way to becoming the No. 1 beamline facility for biology in the world by early 2016, thanks to a jumpstart grant of $4.6 million from the National Institute of Biomedical Imaging and Bioengineering, a component of the National Institutes of Health.

24 Sep 2014

Scientists develop "electronic skin" for earlier identification of breast cancer

For detecting cancer, manual breast exams seem low-tech compared to other methods such as MRI. But scientists are now developing an "electronic skin" that "feels" and images small lumps that fingers can miss.

11 Sep 2014

Lucideon announces collaboration with Knight Mechanical Testing

Lucideon, an international provider of materials development, testing and assurance, and Knight Mechanical Testing, an independent mechanical testing laboratory, are pleased to announce that they have entered into a Marketing and Commercial Collaboration Agreement. The agreement means that both partners will now be to offer a complete portfolio of testing and analysis services to the orthopaedic industry.

From Lucideon 10 Sep 2014

Research reveals extent to which German beers may be contaminated by microplastics

If you're going to Oktoberfest next month to enjoy the delights of German beer, you might get more than you bargained for. New research has revealed the extent to which German beers may be contaminated by foreign substances, most notably, microplastics.

4 Sep 2014

American scientists develop another groundbreaking click concept: SuFEx

The coupling of molecular building blocks nearly as easy as “snapping” them together can be realized by means of the “click chemistry” tool kit. American scientists have now introduced another achievement for the click concept in the journal Angewandte Chemie: the sulfur fluoride exchange reaction (SuFEx) can be used to form robust inorganic bridges between carbon centers and opens up a fully unexplored area of chemistry with countless new molecules that could form the basis for new drugs, diagnostics, plastics, “intelligent” materials, and many other products.

2 Sep 2014

Researchers develop new test to identify sickle cell disease in minutes

Within minutes after birth, every child in the U.S. undergoes a battery of tests designed to diagnose a host of conditions, including sickle cell disease. Thousands of children born in the developing world, however, aren't so lucky, meaning many suffer and die from the disease each year.

2 Sep 2014

Novel process could help the world deal with agricultural and plastic waste problems

Your chairs, synthetic rugs and plastic bags could one day be made out of cocoa, rice and vegetable waste rather than petroleum, scientists are now reporting. The novel process they developed and their results, which could help the world deal with its agricultural and plastic waste problems, appear in the ACS journal Macromolecules.

21 Aug 2014