Toxin News and Research

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New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

Malaria protein could one day help stop cancer

Scientists at the University of British Columbia, Vancouver Coastal Health and the BC Cancer Agency have discovered a protein from malaria that could one day help stop cancer in its tracks.

13 Oct 2015

Danish researchers face possible breakthrough in fight against cancer

The hunt for a vaccine against malaria in pregnant women has provided an unexpected side benefit for Danish researchers, namely what appears to be an effective weapon against cancer. The scientists behind the vaccine aim for tests on humans within four years.

13 Oct 2015

Stanford researchers successfully defeat C. difficile bacteria

Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.

24 Sep 2015

Novel graphene oxide-based biosensor may speed up development of new drugs against HIV, cancer

Longing to find a cure for cancer, HIV and other yet incurable diseases, researchers have already tried out hundreds of drugs, each requiring preclinical and clinical testing with live subjects. How many chemical agents more to try? Moving at such rate, will we find the cure during our lifetime? One of the easiest ways to speed up the drug development process is to simply perform it outside of the living body (e.g., by watching the substances react with the smallest pieces of live tissue and thus quickly predicting the overall effect it will make to the body when inside).

23 Sep 2015

Gene study reveals how a strain of E. coli evolved to become potentially fatal infection

A strain of E. coli became a potentially fatal infection in the UK around 30 years ago, when it acquired a powerful toxin, a gene study has revealed.

22 Sep 2015

Takeda Pharmaceutical's $2.37 billion settlement over Actos drug moves forward

MT Services LLC, a Lawsuit Settlement News Reporting Company which operates lawsuitsettlementnews.com, announced today that Takeda Pharmaceutical Co.'s $2.37 billion settlement over their diabetes drug Actos is going through and moving forward. Actos drug maker, Takeda, agreed to toss in another $100 million if enough claimants signed up with matching settlement criteria – 97% of the claims to be exact.

21 Sep 2015

Aridis' AR-301 granted FDA Fast Track Designation for treatment of pneumonia caused by S. aureus

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel anti-infectives and immunotherapies for infectious diseases, announced today that the U.S. Food and Drug Administration granted Fast Track Designation to AR-301, the Company's fully human anti-Staphylococcal alpha-toxin IgG1 monoclonal antibody (mAb).

11 Sep 2015

Research opens up potential new pathways to vaccine development against HA-MRSA

New research led by NYU Langone Medical Center has uncovered why a particular strain of Staphylococcus aureus -- known as HA-MRSA -- becomes more deadly than other variations. These new findings open up possible new pathways to vaccine development against this bacterium, which the Centers for Disease Control and Preventions says accounts for over 10,000 deaths annually, mostly among hospital patients.

10 Sep 2015

Botulinum toxin A improves muscle tone in hemiparesis

A single injection of abobotulinumtoxinA into upper limb muscles significantly reduces muscle tone in patients with hemiparesis following stroke or traumatic brain injury, study findings show.

9 Sep 2015

Agent Orange exposure raises MGUS risk

The risk of monoclonal gammopathy of undetermined significance is significantly higher in individuals exposed than those not exposed to Agent Orange, shows a study of US Air Force personnel.

9 Sep 2015

New UC Davis study suggests that popular molecular tests over-diagnose C. difficile infections

Clostridium difficile is a common cause of infection and diarrhea in hospitalized patients, but a new study by UC Davis pathologists suggests that many patients are mistakenly diagnosed and do not need antibiotic treatment. As a result, patients are likely being over-diagnosed and over-treated, adding to concerns about antibiotic resistance, damage to the "good" bacteria that live in people's intestines, and increased health-care costs.

9 Sep 2015

Molecular evolution in separate species predicts convergence of toxin resistance

Researchers at LSTM have shown that under certain circumstances evolution can be highly predictable, especially in terms of how creatures become resistant to dangerous toxins.

8 Sep 2015

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Oxis Biotech, Inc., a wholly owned subsidiary of Oxis International, Inc., announced today the execution of an exclusive worldwide license agreement to further develop and commercialize DT2219ARL, a novel therapy for the treatment of various human B cell cancers, leukemias and lymphomas.

8 Sep 2015

Research: Mechanisms behind bacterial warfare could be harnessed to target pathogenic bacteria

Two UC Santa Barbara graduate students have demonstrated how certain microbes exploit proteins in nearby bacteria to deliver toxins and kill them.

28 Aug 2015

European chestnut leaves contain ingredients with power to disarm deadly staph bacteria

Leaves of the European chestnut tree contain ingredients with the power to disarm dangerous staph bacteria without boosting its drug resistance, scientists have found.

24 Aug 2015

NIAID exercises option to advance development of Soligenix's heat stabilized ricin toxin vaccine

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that the National Institute of Allergy and Infectious Diseases has exercised its option to advance the development of Soligenix's heat stabilized ricin toxin vaccine, RiVax.

19 Aug 2015

Takeda's $2.37 billion settlement over Actos didn't attract enough claimants to participate in the deal

MT Services LLC, a Lawsuit Settlement News Reporting Company which operates lawsuitsettlementnews.com, announced today that Takeda Pharmaceutical Co.'s $2.37 billion settlement didn't attract enough claimants to participate in the deal, which said the company would fund the deal after 95% of claimants joined it.

18 Aug 2015

MU researcher proposes method to identify human vulnerabilities

Historically, males have been considered the vulnerable sex, sometimes called "male vulnerability." Charles Darwin noted that boys are more likely to die in infancy than girls and have a higher risk of premature death throughout their lifetimes. Now, a researcher at the University of Missouri suggests that research in "male vulnerability" should be expanded to include "female vulnerability."

18 Aug 2015

UC San Diego researchers discover cells that regenerate better liver tissue than ordinary liver cells

The mechanisms that allow the liver to repair and regenerate itself have long been a matter of debate. Now researchers at University of California, San Diego School of Medicine have discovered a population of liver cells that are better at regenerating liver tissue than ordinary liver cells, or hepatocytes.

14 Aug 2015

Toxin News and Research

New research shows nicotine increases codeine-induced analgesia

Malaria protein could one day help stop cancer

Danish researchers face possible breakthrough in fight against cancer

Stanford researchers successfully defeat C. difficile bacteria

Novel graphene oxide-based biosensor may speed up development of new drugs against HIV, cancer

Gene study reveals how a strain of E. coli evolved to become potentially fatal infection

Takeda Pharmaceutical's $2.37 billion settlement over Actos drug moves forward

Aridis' AR-301 granted FDA Fast Track Designation for treatment of pneumonia caused by S. aureus

Research opens up potential new pathways to vaccine development against HA-MRSA

Botulinum toxin A improves muscle tone in hemiparesis

Agent Orange exposure raises MGUS risk

New UC Davis study suggests that popular molecular tests over-diagnose C. difficile infections

Molecular evolution in separate species predicts convergence of toxin resistance

Oxis Biotech executes worldwide license agreement to develop, commercialize novel cancer therapy

Research: Mechanisms behind bacterial warfare could be harnessed to target pathogenic bacteria

European chestnut leaves contain ingredients with power to disarm deadly staph bacteria

NIAID exercises option to advance development of Soligenix's heat stabilized ricin toxin vaccine

Takeda's $2.37 billion settlement over Actos didn't attract enough claimants to participate in the deal

MU researcher proposes method to identify human vulnerabilities

UC San Diego researchers discover cells that regenerate better liver tissue than ordinary liver cells

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