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Vaccination studies from Mercer University to be unveiled at AAPS’ NBC

Vaccination studies from Mercer University (Ga.) headline the groundbreaking research being unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference.

21 May 2012

Auranofin effective against amoebas in lab and animal studies

A team of researchers from UCSF and UC San Diego has identified an approved arthritis drug that is effective against amoebas in lab and animal studies, suggesting it could offer a low-dose, low cost treatment for the amoebic infections that cause human dysentery throughout the world.

21 May 2012

Scientists map how XIAP protein activates vital component of immune defence system

Defects in the gene that encodes the XIAP protein result in a serious immune malfunction. Scientists used biochemical analyses to map the protein's ability to activate vital components of the immune system. Their results have recently been published in Molecular Cell, a journal of international scientific repute.

18 May 2012

Effectiveness of 'quorum sensing' directly depends on density of bacterial populations

Scientists at The University of Nottingham have opened the way for more accurate research into new ways to fight dangerous bacterial infections by proving a long-held theory about how bacteria communicate with each other.

18 May 2012

Tiny filter could fight against tuberculosis

A tiny filter could have a big impact around the world in the fight against tuberculosis. Using the traditional microscope-based diagnosis method as a starting point, a University of Florida lung disease specialist and colleagues in Brazil have devised a way to detect more cases of the bacterial infection.

18 May 2012

Treating prenatal maternal infections could improve birth outcomes, study suggests

Clinical trials are underway to test an azithromycin-based combination treatment for pregnant women, "which could tackle some of the leading preventable causes of death for babies in sub-Saharan Africa," according to researchers from the London School of Hygiene & Tropical Medicine (LSHTM), who published a report on Wednesday in the Journal of the American Medical Association.

17 May 2012

Biologists engineer algae to produce potential candidates for malarial vaccine

Biologists at the University of California, San Diego have succeeded in engineering algae to produce potential candidates for a vaccine that would prevent transmission of the parasite that causes malaria, an achievement that could pave the way for the development of an inexpensive way to protect billions of people from one of the world's most prevalent and debilitating diseases. Initial proof-of-principle experiments suggest that such a vaccine could prevent malaria transmission.

17 May 2012

Dual prevalence of STIs/RTIs and malaria in pregnancy found among women in sub-Saharan Africa

A review of studies reporting estimates of the prevalence of sexually transmitted infections/reproductive tract infections (STIs/RTIs) and malaria over the past 20 years suggests that a considerable burden of malaria and STIs/RTIs exists among pregnant women attending antenatal (before birth) facilities in sub-Saharan Africa, according to a review and meta-analysis of previous studies published in the May 16 issue of JAMA, a theme issue on Global Health.

16 May 2012

Achaogen’s plazomicin and levofloxacin safe and effective in treating cUTI, acute pyelonephritis

Achaogen, Inc. announced today that all objectives were met in the company's multi-national Phase 2 study of plazomicin compared to levofloxacin for the treatment of complicated urinary tract infections (cUTI) and acute pyelonephritis in adults.

16 May 2012

HMO critically important in understanding how breastfeeding protects babies

A new University of Illinois study shows that human milk oligosaccharides, or HMO, produce short-chain fatty acids that feed a beneficial microbial population in the infant gut. Not only that, the bacterial composition adjusts as the baby grows older and its needs change.

15 May 2012

Microbiome of young men depends upon circumcision status, patterns of sexual activity

The first study using cultivation independent sequencing of the microorganisms in the adolescent male urinary tract has revealed that the composition of microbial communities colonizing the penis in young men depends upon their circumcision status and patterns of sexual activity.

15 May 2012

Researchers uncover new way to stimulate activity of immune cell opiate receptors

Researchers at Rutgers University have uncovered a new way to stimulate activity of immune cell opiate receptors, leading to efficient tumor cell clearance.

14 May 2012

Poor planning, revenue-driven surgery force patients home too early

Revenue-driven surgery and poor planning drive some surgical patients home too early, concludes a pair of logistical studies conducted by researchers at the University of Maryland's Robert H. Smith School of Business.

14 May 2012

Killer coating destroys bacteria and fungi on contact

Better than antibiotics, it is being used in contact lenses to prevent infections and biomedical products are the next stage

11 May 2012

Bacteria in digestive tracts compete against invading bacteria

From tiny villages in developing nations to suburban kitchens in the United States, dangerous strains of E. coli bacteria sicken millions of people each year - and kill untold numbers of children.

11 May 2012

Trovagene receives European patent titled, ‘Methods for Detection of Nucleic Acid Sequences in Urine’

Trovagene, Inc., a developer of trans-renal molecular diagnostics, announced it has received notice of issuance of European Patent No. 2216416 entitled "Methods for Detection of Nucleic Acid Sequences in Urine."

11 May 2012

International community, U.S. should increase resources, mandate for fighting NCDs in developing world

In this Foreign Affairs essay, Thomas Bollyky, a senior fellow for global health, economics and development at the Council on Foreign Relations, examines the increase of non-communicable diseases (NCDs) in the developing world.

10 May 2012

Researchers use clever screening methods to speed vaccine production

Infectious diseases-both old and new-continue to exact a devastating toll, causing some 13 million fatalities per year around the world. Vaccines remain the best line of defense against deadly pathogens and now Kathryn Sykes and Stephen Johnston, researchers at Arizona State University's Biodesign Institute, along with co-author Michael McGuire from the University of Texas Southwestern Medical Center are using clever functional screening methods to attempt to speed new vaccines into production that are both safer and more potent.

10 May 2012

One in six cancer cases worldwide related to preventable or curable infections

New research shows that one in six cancers - amounting to two million a year globally - are caused by largely treatable or preventable infections.

9 May 2012

Free whooping cough vaccine cut concerns experts

Heath experts are concerned that parents and carers of newborn babies will stop getting the whooping cough vaccine after the state government cut its free immunisation program in the midst of a fatal epidemic.

9 May 2012

Bacterial News and Research

Vaccination studies from Mercer University to be unveiled at AAPS’ NBC

Auranofin effective against amoebas in lab and animal studies

Scientists map how XIAP protein activates vital component of immune defence system

Effectiveness of 'quorum sensing' directly depends on density of bacterial populations

Tiny filter could fight against tuberculosis

Treating prenatal maternal infections could improve birth outcomes, study suggests

Biologists engineer algae to produce potential candidates for malarial vaccine

Dual prevalence of STIs/RTIs and malaria in pregnancy found among women in sub-Saharan Africa

Achaogen’s plazomicin and levofloxacin safe and effective in treating cUTI, acute pyelonephritis

HMO critically important in understanding how breastfeeding protects babies

Microbiome of young men depends upon circumcision status, patterns of sexual activity

Researchers uncover new way to stimulate activity of immune cell opiate receptors

Poor planning, revenue-driven surgery force patients home too early

Killer coating destroys bacteria and fungi on contact

Bacteria in digestive tracts compete against invading bacteria

Trovagene receives European patent titled, ‘Methods for Detection of Nucleic Acid Sequences in Urine’

International community, U.S. should increase resources, mandate for fighting NCDs in developing world

Researchers use clever screening methods to speed vaccine production

One in six cancer cases worldwide related to preventable or curable infections

Free whooping cough vaccine cut concerns experts

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