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AF care ‘inadequate’

Cardiology experts are supporting a call for greater attention to diagnosis and management of atrial fibrillation in primary care to prevent strokes.

10 Jul 2012

Phase III darexaban results revealed

The direct oral factor Xa inhibitor darexaban is effective for the prevention of venous thromboembolism in Japanese patients undergoing major abdominal surgery, researchers find.

10 Jul 2012

High-dose vitamin D recommended for over 65s

Meta-analysis findings support recommendations from the Institute of Medicine that people aged 65 years and older should routinely receive 800 IU of vitamin D per day.

10 Jul 2012

Kidney treatment could affect mouth health

Study results indicate a positive association between the type of treatment modality chronic kidney disease patients receive and the likelihood for them having periodontitis.

10 Jul 2012

Neuroprotective effects underpin fingolimod benefits in MS

Fingolimod therapy reduces inflammatory activity and tissue loss in the brains of patients with multiple sclerosis, shows further analysis of the FREEDOMS trial.

10 Jul 2012

Poor vaccine uptake blamed for polio rise in Pakistan, Afghanistan

The number of cases of poliomyelitis per year in Pakistan and Afghanistan has more than doubled since 2006 despite improvements in available vaccine efficacy, show study findings in The Lancet.

10 Jul 2012

Effective ketoprofen dose identified for pig endotoxins

Compared with tap water, treatment with ketoprofen significantly reduces the rectal temperature and total clinical scores among pigs challenged with the Escherichia coli endotoxin, report researchers.

10 Jul 2012

Self-management of anticoagulants in elderly could be beneficial

Elderly patients who self-manage their oral anticoagulant treatment have a comparable treatment-related quality of life to those who undergo routine care, and may even experience higher treatment satisfaction, researchers say.

10 Jul 2012

Iron supplementation decreases fatigue by almost 50% in nonanemic women

Iron supplementation reduced fatigue by almost 50% in women who are low in iron but not anemic, according to the results of a clinical trial published July 9 in CMAJ (Canadian Medical Association Journal).

10 Jul 2012

Enrollment complete in Lux Biosciences Luveniq Phase 3 study for non-infectious uveitis

Lux Biosciences, Inc. today announced the completion of patient enrollment in its Phase 3 clinical study of Luveniq (oral voclosporin) for the treatment of non-infectious uveitis. Lux Biosciences anticipates that data from the Phase 3 study will be available early in the first quarter of 2013.

9 Jul 2012

Positive data from Tonix's sublingual TNX-102 PK study for fibromyalgia

Tonix Pharmaceuticals Holding Corp., a specialty pharmaceutical company developing non-addictive treatments for chronic pain syndromes, including fibromyalgia, reported positive data from an animal pharmacokinetic study of its novel sublingual formulation of TNX-102, the Company's very low dose cyclobenzaprine.

9 Jul 2012

Positive interim results from Inspiration's OBI-1 Phase 2/3 study for acquired hemophilia A

Inspiration Biopharmaceuticals, Inc. today reported data from its ongoing Phase 2/3 study evaluating the efficacy of OBI-1, an investigational recombinant porcine factor VIII (FVIII), for the treatment of serious bleeds in people with acquired hemophilia A. According to the interim analysis, seven out of seven trial participants receiving OBI-1 experienced control and subsequent resolution of their bleeds.

9 Jul 2012

Treatment of Schizophrenia receives notice of intention to grant a European patent

BioLineRx (NASDAQ:BLRX)(TASE:BLRX), a biopharmaceutical development company, announced today that it has received from the European Patent Office a notice of intention to grant a European patent claiming the salt of BL-1020, a first-in-class orally available treatment for schizophrenia.

9 Jul 2012

JRD receives FDA priority review designation for XARELTO sNDAs to treat PE, DVT

Janssen Research & Development, LLC (Janssen R&D) announced today the U.S. Food and Drug Administration (FDA) has assigned a priority review designation to the supplemental New Drug Applications (sNDAs) filed on May 2, 2012 for XARELTO (rivaroxaban), an oral anticoagulant, seeking new indications to treat patients with deep vein thrombosis (DVT), pulmonary embolism (PE), and to prevent recurrent DVT and PE.

9 Jul 2012

Ampio announces results from Optina trial on DME

Ampio Pharmaceuticals, Inc., a biopharmaceutical company developing innovative proprietary drugs for inflammation, eye disease, kidney disease, CNS disease, metabolic disease and male sexual dysfunction and conducting clinical trials on its three lead drugs (Ampion, Optina & Zertane), announced the significant results from their further analysis of its Optina trial on DME.

9 Jul 2012

More than 570 pioneering dentists assembled at MDL USA's World Dental Forum

Modern Dental Laboratory USA (MDL USA) assembled a group of 570 pioneering dentists from all over the world to come together at their second-annual World Dental Forum in Hong Kong and Shenzhen, China from May 31 to June 3, 2012.

8 Jul 2012

Research roundup: Crowded emergency departments, expensive HIV drugs, high deductible insurance plans

Skin In The Game: How Consumer-Directed Plans Affect The Cost And Use Of Health Care -- Consumer-directed health plans, which feature lower premiums and higher deductibles than traditional plans, are designed to reduce costs by discouraging unnecessary care. This brief describes a study of more than 800,000 households that switched from a traditional employer-based plan to a consumer-based plan.

7 Jul 2012

FDA action affects companies that manufacture and distribute unapproved oxycodone drugs

The U.S. Food and Drug Administration today issued a Federal Register notice instructing companies to stop manufacturing and distributing certain unapproved drugs that contain oxycodone. The notice is part of the FDA's Unapproved Drugs Initiative to remove unapproved new drugs from the market.

6 Jul 2012

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

Eltrombopag, a drug that was designed to stimulate production of platelets from the bone marrow and thereby improve blood clotting, can raise blood cell levels in some people with severe aplastic anemia who have failed all standard therapies.

5 Jul 2012

UN food standards body agrees on new regulations to protect health of consumers across the world

The UN food standards body has agreed on new regulations - including the maximum level of melamine in liquid milk formula for babies - to protect the health of consumers across the world. Other measures adopted include new food safety standards on seafood, melons, dried figs and food labelling.

5 Jul 2012

Oral News and Research

AF care ‘inadequate’

Phase III darexaban results revealed

High-dose vitamin D recommended for over 65s

Kidney treatment could affect mouth health

Neuroprotective effects underpin fingolimod benefits in MS

Poor vaccine uptake blamed for polio rise in Pakistan, Afghanistan

Effective ketoprofen dose identified for pig endotoxins

Self-management of anticoagulants in elderly could be beneficial

Iron supplementation decreases fatigue by almost 50% in nonanemic women

Enrollment complete in Lux Biosciences Luveniq Phase 3 study for non-infectious uveitis

Positive data from Tonix's sublingual TNX-102 PK study for fibromyalgia

Positive interim results from Inspiration's OBI-1 Phase 2/3 study for acquired hemophilia A

Treatment of Schizophrenia receives notice of intention to grant a European patent

JRD receives FDA priority review designation for XARELTO sNDAs to treat PE, DVT

Ampio announces results from Optina trial on DME

More than 570 pioneering dentists assembled at MDL USA's World Dental Forum

Research roundup: Crowded emergency departments, expensive HIV drugs, high deductible insurance plans

FDA action affects companies that manufacture and distribute unapproved oxycodone drugs

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

UN food standards body agrees on new regulations to protect health of consumers across the world

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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