Next Generation News and Research

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Transgenics sped up

A new method of constructing artificial plant chromosomes from small rings of naturally occurring plant DNA can be used to transport multiple genes at once into embryonic plants where they are expressed, duplicated as plant cells divide, and passed on to the next generation -- a long-term goal for those interested in improving agricultural productivity.

19 Oct 2007

Massive reanalysis of genome data solves case of the lethal genes

It is better to be looked over than overlooked, Mae West supposedly said. These are words of wisdom for genome data-miners of today.

19 Oct 2007

Lilly and MacroGenics to develop and commercialize teplizumab

Eli Lilly and Company and MacroGenics, Inc. have announced that the two companies have entered into a global strategic alliance to develop and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next generation anti-CD3 molecules for use in the treatment of autoimmune diseases.

19 Oct 2007

Abbott creates one molecule with two antibody functions

Abbott has reported that its scientists are the first to discover a proprietary technology that combines the function and specificity of two or more monoclonal antibodies (mAbs) into one molecular entity that demonstrates drug-like properties and manufacturing feasibility.

19 Oct 2007

Direct selection of human genomic loci by microarray hybridization

Researchers at Baylor College of Medicine and Roche NimbleGen Inc., a fully integrated part of Roche Applied Science, have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip microarrays in preparation for high-throughput 454 Sequencing.

16 Oct 2007

Launch of new transatlantic research link

Scientists in London will be able to use and manipulate, in real-time, leading multi-million dollar scientific instruments and technology in the USA, following the official launch of the Global Lab at Imperial College London.

15 Oct 2007

Microarray-based genomic selection accelerates discovery of subtle DNA variations

A new technology developed by scientists at Emory University will allow researchers to more easily discover subtle and overlooked genetic variations that may have serious consequences for health and disease.

15 Oct 2007

Professional welders risk losing their sense of smell

Researchers at the University of Pennsylvania School of Medicine have found that professional welders who work in enclosed spaces with poor ventilation may be at risk for loss of sense of smell. The study appears in Neurology .

12 Oct 2007

Penn awarded $2.1 million grant for cardiovascular research

Cardiac researchers at the University of Pennsylvania have received a $2.1 million grant from the National Institutes of Health (NIH) to pioneer studies in cardiovascular disease management and participate in a novel collaboration network to develop and implement research in this critically important field.

12 Oct 2007

New molecules discovered that block cancer cells from modifying cell DNA

Researchers have discovered new small molecules that may prevent prostate cancer cells from turning off normal genes in a process that transforms normal cells into cancer cells. This significant discovery in the field of epigenetics has immediate implications in the development of new diagnostic tests and cancer medications.

12 Oct 2007

Link between woman's hips and daughter's risk of breast cancer

In a study of the maternity records of more than 6,000 women, David J.P. Barker, M.D., Ph.D., and Kent Thornburg, Ph.D., of Oregon Health & Science University discovered a strong correlation between the size and shape of a woman's hips and her daughter's risk of breast cancer.

9 Oct 2007

Wyeth Pharmaceuticals to acquire Haptogen

Wyeth Pharmaceuticals, a division of Wyeth has announced the signing of a definitive agreement under which it has acquired Haptogen Ltd., a Scottish company based in Aberdeen that is focused on the discovery of biopharmaceutical therapies.

8 Oct 2007

Cancer trial combines multiple drugs to attack blood vessel formation in patients with kidney cancer

In the first clinical trial of its kind, researchers at the University of Pennsylvania School of Medicine and the Abramson Cancer Center will lead a nationwide test of anti-cancer drug combinations that target blood vessel growth in patients with advanced kidney cancer.

4 Oct 2007

Default options for medicine, healthcare

Anyone who has ever tried to set up an internet account or wants to make a purchase on a company's website, has experienced the ‘default option,' an event or condition that will be set in place if no alternative is actively chosen.

3 Oct 2007

Scientists perform computer simulation that shows how proteins vibrate in a crystal

An international collaboration directed by an Oak Ridge National Laboratory researcher has performed the first-ever atomic-detail computer simulation of how proteins vibrate in a crystal.

27 Sep 2007

Adnexus Therapeutics to become a subsidiary of Bristol-Myers Squibb

Bristol-Myers Squibb and Adnexus Therapeutics have announced the companies have signed a definitive agreement under which Bristol-Myers Squibb will acquire privately held Adnexus Therapeutics, developer of a new therapeutic class of biologics called Adnectins.

25 Sep 2007

New UK stem cell and regenerative medicine research centre

The new Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM) will be officially opened at the University of Nottingham on the 21st September, 2007 by Sir Keith O’Nions, Director General Science and Innovation at the Department for Innovation, Universities and Skills.

24 Sep 2007

Weill Cornell Medical College to lead new NYC translational research collaboration

Weill Cornell Medical College has been selected by the National Center for Research Resources (NCRR), of the National Institutes of Health (NIH), to establish and lead a new Clinical and Translational Science Center (CTSC), creating an ambitious and innovative network for biomedical collaboration on New York's Upper East Side.

20 Sep 2007

3-D Petri dish that grows cells in three dimensions

A team of Brown University biomedical engineers has invented a 3-D Petri dish that can grow cells in three dimensions, a method that promises to quickly and cheaply produce more realistic cells for drug development and tissue transplantation.

20 Sep 2007