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New molecule reduces diabetic patients' higher risk of developing dementia, Alzheimer's

Researchers at the Hebrew university of Jerusalem have created a molecule that could potentially lower diabetic patients' higher risk of developing dementia or Alzheimer's disease.

28 Jan 2014

Curie-Cancer, Servier renew partnership to identify new therapeutic targets for triple negative breast cancer

Curie-Cancer, the body which leads the Institut Curie's industry partner research activity, and Servier, today announce that they have renewed their partnership with the aim of identifying therapeutic targets for treating ‘triple negative’ breast cancers. The partnership will continue for a further three years.

28 Jan 2014

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

In normal development, all cells turn off genes they don’t need, often by attaching a chemical methyl group to the DNA, a process called methylation. Historically, scientists believed methyl groups could only stick to a particular DNA sequence: a cytosine followed by a guanine, called CpG. But in recent years, they have been found on other sequences, and so-called non-CpG methylation has been found in stem cells, and in neurons in the brain.

28 Jan 2014

New modular structures 'glued' with DNA to deliver cancer medications

A team of researchers at the University of Toronto has discovered a method of assembling "building blocks" of gold nanoparticles as the vehicle to deliver cancer medications or cancer-identifying markers directly into cancerous tumors.

28 Jan 2014

Researchers discover unusually large bacteriophage that infects anthrax bacterium

From a zebra carcass on the plains of Namibia in Southern Africa, an international team of researchers has discovered a new, unusually large virus (or bacteriophage) that infects the bacterium that causes anthrax.

28 Jan 2014

Changes in SirT1 protein can prevent excess metabolic stress associated with obesity, diabetes and aging

Researchers find changes to protein SirT1 can prevent excess metabolic stress associated with obesity, diabetes and aging.

27 Jan 2014

New biomarker for stress in wild animals facing global climate change

Chemical analyses by neuroscientist Jerrold Meyer and colleagues at the University of Massachusetts Amherst are helping to establish hair cortisol concentration (HCC) as an important new biomarker for stress in wild animals facing global climate change.

25 Jan 2014

Researchers discover mechanism that controls activity of LRRK2 in Parkinson's disease

In one variant of Parkinson's disease, the enzyme LRRK2 plays a central role. Scientists at the University of Kassel have now discovered a mechanism that controls the activity of LRRK2.

24 Jan 2014

Scientists identify critical regulator of molecule deeply involved in progression of Alzheimer's

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer's disease.

24 Jan 2014

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division.

24 Jan 2014

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease.

23 Jan 2014

New easy-to-use risk calculator helps predict heart failure patients' chances of survival

A UCLA team has developed an easy-to-use "risk calculator" that helps predict heart failure patients' chances of survival for up to five years and assists doctors in determining whether more or less aggressive treatment is appropriate.

23 Jan 2014

Scientists develop new genetic platform that yields novel antibiotic from ocean bacteria

Scientists at the University of California, San Diego have developed a new genetic platform that allows efficient production of naturally occurring molecules, and have used it to produce a novel antibiotic compound.

23 Jan 2014

Chinese and American researchers introduce new approach to gene therapy

Resistance of tumor cells toward multiple cytostatic drugs is a serious problem in cancer treatment. In the journal Angewandte Chemie, a team of Chinese and American researchers has now introduced a new approach to gene therapy that could counter this problem: The gene that codes for resistance is “silenced” through the use of an ingenious nanocomplex.

22 Jan 2014

New oral drug appears to offer hope for fighting indolent non-Hodgkin lymphoma

Slow-growing, or indolent, non-Hodgkin lymphomas are difficult to treat, with most patients relapsing repeatedly and the disease becoming increasingly resistant to therapy over time.

22 Jan 2014

Scientists identify specific enzyme essential for brain development

Scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna have identified a specific enzyme, histone deacetylase 2 (HDAC2), as essential for brain development. The findings published in Development are important to advance the development of new drugs to treat neurological diseases.

22 Jan 2014

Scientists showcase HDL nanotherapy that may provide solution to repeat heart attacks

Up to 30 percent of heart attack patients suffer a new heart attack because cardiologists are unable to control inflammation inside heart arteries - the process that leads to clots rupturing and causing myocardial infarction or stroke.

22 Jan 2014

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Embryonal tumours with multilayered rosettes (ETMR) are rare, deadly brain tumours that affect mainly children below the age of 4 years. There are 300 cases reported but probably there are many more as this tumour is often misdiagnosed.

21 Jan 2014

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

Forest Laboratories, Inc., a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market, announced that reported diluted earnings per share equaled $0.07 in the third quarter of fiscal 2014, compared to a reported loss per share of ($0.58) in the third quarter of fiscal 2013. The third quarter of fiscal 2014 included a $45 million charge ($28.2 million net of tax) related to Project Rejuvenate.

21 Jan 2014

European Commission approves ViiV Healthcare's Tivicay for treatment of HIV infected adults

ViiV Healthcare today announced that the European Commission has approved Tivicay (dolutegravir), an integrase inhibitor, for use in combination with other anti-retroviral medicinal products for the treatment of HIV infected adults and adolescents above 12 years of age.

21 Jan 2014

Enzyme News and Research

New molecule reduces diabetic patients' higher risk of developing dementia, Alzheimer's

Curie-Cancer, Servier renew partnership to identify new therapeutic targets for triple negative breast cancer

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

New modular structures 'glued' with DNA to deliver cancer medications

Researchers discover unusually large bacteriophage that infects anthrax bacterium

Changes in SirT1 protein can prevent excess metabolic stress associated with obesity, diabetes and aging

New biomarker for stress in wild animals facing global climate change

Researchers discover mechanism that controls activity of LRRK2 in Parkinson's disease

Scientists identify critical regulator of molecule deeply involved in progression of Alzheimer's

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

New easy-to-use risk calculator helps predict heart failure patients' chances of survival

Scientists develop new genetic platform that yields novel antibiotic from ocean bacteria

Chinese and American researchers introduce new approach to gene therapy

New oral drug appears to offer hope for fighting indolent non-Hodgkin lymphoma

Scientists identify specific enzyme essential for brain development

Scientists showcase HDL nanotherapy that may provide solution to repeat heart attacks

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

European Commission approves ViiV Healthcare's Tivicay for treatment of HIV infected adults

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