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Researchers uncover unexpected mechanism of glucose sensing in skeletal muscles

It's obvious that the taste buds on the tongue can detect sugar. And after a meal, beta cells in the pancreas sense rising blood glucose and release the hormone insulin - which helps the sugar enter cells, where it can be used by the body for energy.

5 May 2017

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Immunotherapy, which has achieved remarkable results in late-stage lung cancer patients, can also hold great hope for newly diagnosed patients, cutting the deadly disease off before it has the chance to take hold and offering a potential cure, according to a new Mount Sinai study published today in Cell.

4 May 2017

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Among scientists specializing in the area, the mechanisms behind the signaling function of the Hedgehog (Hh) receptor pathway remain a mystery. Xiaoyen Zheng, Ph.D., assistant professor of anatomy and regenerative biology at the George Washington University School of Medicine and Health Sciences, who recently received a $1.7 million grant from the National Institutes of Health and National Institute of General Medical Sciences, is determined to learn more about the Hh pathway.

4 May 2017

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.

4 May 2017

Permanent funding solution essential to ensure future of unique primary care residency program

It's too soon for Shayla Durfey to know whether she'll apply for a Teaching Health Centers residency when she graduates from the Warren Alpert Medical School of Brown University in a few years -- but as she and two professors write online in JAMA, the unique opportunity won't still exist for her or other medical students without action from Congress.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

Study: Patients operated by higher volume mitral surgeons experience lower mortality and reoperations

Surgeons who perform more than 25 mitral valve operations a year are more likely to perform repairs that are durable, and their patients are more likely to be alive a year after the operation, than when operations are performed by lower-volume surgeons, an Icahn School of Medicine at Mount Sinai study has found.

3 May 2017

IU researchers develop new method to grow inner ear tissue from human stem cells

Researchers at Indiana University School of Medicine have successfully developed a method to grow inner ear tissue from human stem cells - PhDa finding that could lead to new platforms to model disease and new therapies for the treatment of hearing and balance disorders.

3 May 2017

Impaired effects of insulin can increase cancer risk, shows study

Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone insulin in their blood can experience increased risks of cancer. Surprisingly, however, Joslin Diabetes Center researchers now have discovered that impaired effects of insulin also can boost these risks.

3 May 2017

Study finds no link between gluten intake and heart disease risk in people without celiac disease

A study of more than 100,000 men and women revealed that dietary gluten is not associated with heart disease risk in people without celiac disease. The findings also suggest that limiting whole grains as part of a low-gluten diet may increase the risk of heart disease in people who do not have celiac disease.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

ARVO 2017 to showcase latest advances in treatments for eye disease and blindness

The Annual Meeting of the Association for Research in Vision and Ophthalmology is the largest gathering of eye and vision researchers in the world, with over 11,000 attendees from more than 75 countries.

2 May 2017

New research begins at University of Warwick to understand cause of brain tumors

A team based at the University's Warwick Medical School will study brain tumor cells in the lab to understand more about the cell division process, and how it can cause cancer when it goes wrong.

2 May 2017

New computational approach could enable more patients with epilepsy to benefit from surgery

A computational approach developed at Boston Children's Hospital, described in the journal Neurosurgery, published online May 2, 2017, could enable more patients with epilepsy to benefit from surgery when medications do not help.

2 May 2017

Positive social support from adult children linked to reduced dementia risk

Positive social support from adult children is associated with reduced risk of developing dementia, according to a new research published today.

2 May 2017

Study finds uneven distribution of telemedicine services for mental health in rural areas

Newly published research by Harvard Medical School and the RAND Corporation reveals a dramatic growth in the use of telemedicine for the diagnosis and treatment of mental health disorders in rural areas, but strikingly uneven distribution of services across states.

2 May 2017

Researchers uncover molecule that may explain smoking-CHD connection

Cigarette smoking accounts for about one-fifth of cases of coronary heart disease, one of the leading causes of death worldwide, but precisely how smoking leads to CHD has long been unclear.

2 May 2017

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

A shorter course of radiation therapy given to breast cancer patients following mastectomy is safe and effective and cuts treatment time in half. That is according to data from a phase II clinical trial conducted by Rutgers Cancer Institute of New Jersey investigators and other colleagues who examined a hypofractionated regimen given over three weeks versus the traditional six week course of treatment.

2 May 2017

Penn study sheds new light on mysterious powers of spider silk genes

They can be stronger than steel at a mere fraction of weight, and also can be tougher and more flexible. Spider silks also tend not to provoke the human immune system. Some even inhibit bacteria and fungi, making them potentially ideal for surgery and medical device applications.

2 May 2017

Novel strategy may improve survival of grafts, outcomes in high-risk corneal transplant patients

Treating donor corneas with a cocktail of molecules prior to transplanting to a host may improve survival of grafts and, thus, outcomes in high-risk corneal transplant patients, according to a new study led by researchers at Massachusetts Eye and Ear.

2 May 2017

Medical School News and Research

Researchers uncover unexpected mechanism of glucose sensing in skeletal muscles

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Permanent funding solution essential to ensure future of unique primary care residency program

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

Study: Patients operated by higher volume mitral surgeons experience lower mortality and reoperations

IU researchers develop new method to grow inner ear tissue from human stem cells

Impaired effects of insulin can increase cancer risk, shows study

Study finds no link between gluten intake and heart disease risk in people without celiac disease

Researchers uncover new mechanism that explains cause of portal hypertension

ARVO 2017 to showcase latest advances in treatments for eye disease and blindness

New research begins at University of Warwick to understand cause of brain tumors

New computational approach could enable more patients with epilepsy to benefit from surgery

Positive social support from adult children linked to reduced dementia risk

Study finds uneven distribution of telemedicine services for mental health in rural areas

Researchers uncover molecule that may explain smoking-CHD connection

Study finds shorter course of radiation therapy given after mastectomy to be safe and effective

Penn study sheds new light on mysterious powers of spider silk genes

Novel strategy may improve survival of grafts, outcomes in high-risk corneal transplant patients

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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