Protein C News and Research

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Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

A new study demonstrated the efficacy of a newly engineered angiotensin-converting enzyme 2 (ACE2) based immunoadhesin against Omicron and other SARS-CoV-2 VOCs.

30 Sep 2022

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

A recent study explored the diet-exercise-gut microbiome dynamics in male bodybuilders.

30 Sep 2022

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Researchers analyzed genomic sequences of MPXV obtained from 18 patients who contracted MPXV infection between June and July 2022.

30 Sep 2022

Patients with scleroderma have reduced levels of Cathepsin L

Much of the research on scleroderma, a connective tissue disease that causes scarring, or fibrosis, has focused on the increased number of proteins promoting fibrosis in these patients. A Medical University of South Carolina (MUSC) research team took a different tact and measured the levels of an antifibrotic protein, Cathepsin L, in these patients.

30 Sep 2022

Study reveals the role of autophagy in competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process “autophagy.”

30 Sep 2022

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Scientists have identified lucidenic acid A, one of the bioactive compounds of Ganoderma lucidum, as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host cell entry. The study has recently been published in the journal Food and Chemical Toxicology.

29 Sep 2022

Many diverse nanopore research directions and applications beyond DNA sequencing

In a recent Nature Nanotechnology study, researchers describe diverse applications of nanopore-based technology beyond deoxyribonucleic acid (DNA) sequencing. More specifically, the current research focuses on the advancements of this technology within chemistry, biophysics, and nanoscience.

29 Sep 2022

Pluripotent bat stem cells as a model to study novel viruses

Researchers generate induced pluripotent stem cells from bats using to establish bats as a novel in vivo model study species.

29 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Cancer cells 'hijack' a process used by healthy cells to spread around the body, research finds

Cancer Research UK-funded scientists have discovered that cancer cells 'hijack' a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.

29 Sep 2022

Mouse model reveals link between GABA receptors and sleepiness in people with myotonic dystrophy

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for complications when hospitalized.

29 Sep 2022

CAR T-cell therapy produces impressive results in first clinical trial in patients with multiple myeloma

A therapy made of immune system T cells engineered to target a somewhat enigmatic cell protein called GPRC5D antigen produced impressive results in its first clinical trial in patients with multiple myeloma, researchers at Memorial Sloan Kettering Cancer Center (MSK), Dana-Farber Cancer Institute and Roswell Park Comprehensive Cancer Center report in a new study published today by the New England Journal of Medicine.

29 Sep 2022

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

In a new study, researchers compared the transmissibility of novel and emerging SARS-CoV-2 variants.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

One reason that it's so difficult to deliver large protein drugs orally is that these drugs can't pass through the mucus barrier that lines the digestive tract.

28 Sep 2022

UMass Amherst scientists delve into the mysteries of how cells manage stress

In new research recently published in the journal Cell Reports, a team of scientists from the University of Massachusetts Amherst delved into the mysteries of how cells weather stress.

28 Sep 2022

Study reveals how pathogens exploit a key cellular process to intoxicate cells

What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life.

28 Sep 2022

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the brain, with therapeutic and scientific implications.

28 Sep 2022

Protein C News and Research

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Patients with scleroderma have reduced levels of Cathepsin L

Study reveals the role of autophagy in competitive elimination of cancer cells

Bioactive compounds derived from Ganoderma lucidum exhibit anti-SARS-CoV-2 activity

Many diverse nanopore research directions and applications beyond DNA sequencing

Pluripotent bat stem cells as a model to study novel viruses

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

“Mystery gene” matures a main component of the cell skeleton

Cancer cells 'hijack' a process used by healthy cells to spread around the body, research finds

Mouse model reveals link between GABA receptors and sleepiness in people with myotonic dystrophy

CAR T-cell therapy produces impressive results in first clinical trial in patients with multiple myeloma

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Exploring remdesivir resistance in COVID-19-infected transplant recipients

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

UMass Amherst scientists delve into the mysteries of how cells manage stress

Study reveals how pathogens exploit a key cellular process to intoxicate cells

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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