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Study shows possibility to reduce antipsychotic use among nursing home residents with dementia

The use of antipsychotic medication in nearly 100 Massachusetts nursing homes was significantly reduced when staff was trained to recognize challenging behaviors of cognitively impaired residents as communication of their unmet needs, according to a new study led by Jennifer Tjia, MD, MSCE, associate professor of quantitative health sciences.

17 Apr 2017

3D-printed phantom of stenotic intracranial artery helps standardize vessel-wall MRI protocols

A collaboration between stroke neurologists at the Medical University of South Carolina and bioengineers at the University of Massachusetts has led to the creation of a realistic, 3D-printed phantom of a stenotic intracranial artery that is being used to standardize protocols for high-resolution MRI, also known as vessel-wall MRI, at a network of U.S. and Chinese institutions, according to an article published online March 9, 2017 by the Journal of NeuroInterventional Surgery.

17 Apr 2017

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Medical University of South Carolina investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not compromise Th17 cells' effectiveness against large tumors, in the March 9, 2017 issue of JCI Insight.

17 Apr 2017

Technique to minimally disrupt lower suspensory ligaments improves breast reduction outcomes

Research led by Frank Lau, MD, Assistant Professor of Clinical Surgery at LSU Health New Orleans School of Medicine, has found that long-term breast reduction outcomes can be improved by using techniques that minimally disrupt the lower breast suspensory ligaments. The paper, The Sternum-Nipple Distance is Double the Nipple-Inframammary Fold Distance in Macromastia, is published Ahead-of-Print online in the Annals of Plastic Surgery.

14 Apr 2017

Common drugs, uncommon risks? Higher rate of serious problems after short-term steroid use

Millions of times a year, Americans get prescriptions for a week's worth of steroid pills, hoping to ease a backache or quell a nagging cough or allergy symptoms. But a new study suggests that they and their doctors might want to pay a bit more attention to the potential side effects of this medication.

14 Apr 2017

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly.

12 Apr 2017

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

More than 1,800 individuals carrying loss-of-function mutations in both copies of their genes, so-called "human knockouts," are described in the first major study to be published in Nature this week by an international collaboration led by the Perelman School of Medicine at the University of Pennsylvania and colleagues.

12 Apr 2017

Silk garments unlikely to provide benefit for children with eczema

Wearing silk clothing offers no additional benefit for children who suffer from moderate to severe eczema, a study led by researchers at The University of Nottingham has found.

12 Apr 2017

Scientists discover how insulin-producing cells show differences in age

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

12 Apr 2017

3D-printed models provide cost-efficient tool to improve practical experience for surgeons

Cher Zhao recently had the rare opportunity to practice skills belonging to the most advanced surgeons: reconstructive cartilage grafting.

12 Apr 2017

Developmental Split-Brain syndrome discovery

Our group describes a new entity, which we refer to as “Developmental Split-Brain syndrome” which we discovered affected four individuals from three unrelated families. All affected individuals showed disruption of communicating tracts between the right and left side of the brain which meant that there is lack of coordination and communication between the two sides of the brain.

12 Apr 2017

MUSC researchers provide first systemic evidence for safe use of tPA in stroke patients with SCD

Adult patients with sickle cell disease (SCD) who experience a stroke caused by a clot (i.e., ischemic strokes or IS) can be treated safely with tissue plasminogen activator (tPA) if they qualify, report investigators at the Medical University of South Carolina and elsewhere in the March 2017 issue of Stroke.

12 Apr 2017

Scientists discover novel therapeutic target for retinal neovascularization

A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced diabetic eye disease (proliferative diabetic retinopathy).

11 Apr 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Prevalence of high blood pressure found to be six times higher among obese Hispanic adolescents

Obesity raises the prevalence of high blood pressure among adolescents but the increase is particularly pronounced among Hispanics compared to white, African-American or Asian ethnic groups, according to a study by researchers at McGovern Medical School at The University of Texas Health Science Center at Houston. Results were published in the journal Pediatrics.

11 Apr 2017

Identifying serious bowel conditions in under-50s

The fundamental problem is that the symptoms are very similar, or at least some are. Taking your example of IBS – this is characterised by abdominal pain, plus sometimes diarrhoea or constipation. Yet these are key symptoms of abdominal cancer!

11 Apr 2017

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

The Salk Institute has received a $3 million gift from the Glenn Foundation for Medical Research for the second time in 4 years, enabling the Institute to continue investigating the biology of normal human aging and age-related diseases.

10 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Patients with common conditions such as back pain, headaches and upper respiratory infections are more likely to receive tests and services of uncertain or little diagnostic or therapeutic benefit--so-called low-value care--when they seek treatment in primary care clinics located at hospitals rather than at community-based primary care clinics, according to a nationwide study led by researchers at Harvard Medical School and the David Geffen School of Medicine at UCLA.

10 Apr 2017

Tiny light-emitting particles may provide unprecedented detail in biological imaging

For certain frequencies of short-wave infrared light, most biological tissues are nearly as transparent as glass. Now, researchers have made tiny particles that can be injected into the body, where they emit those penetrating frequencies.

10 Apr 2017

Medical School News and Research

Study shows possibility to reduce antipsychotic use among nursing home residents with dementia

3D-printed phantom of stenotic intracranial artery helps standardize vessel-wall MRI protocols

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Technique to minimally disrupt lower suspensory ligaments improves breast reduction outcomes

Common drugs, uncommon risks? Higher rate of serious problems after short-term steroid use

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

Silk garments unlikely to provide benefit for children with eczema

Scientists discover how insulin-producing cells show differences in age

3D-printed models provide cost-efficient tool to improve practical experience for surgeons

Developmental Split-Brain syndrome discovery

MUSC researchers provide first systemic evidence for safe use of tPA in stroke patients with SCD

Scientists discover novel therapeutic target for retinal neovascularization

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

Prevalence of high blood pressure found to be six times higher among obese Hispanic adolescents

Identifying serious bowel conditions in under-50s

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

New study finds link between neural tube defects in infants and neurodegenerative diseases

Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Tiny light-emitting particles may provide unprecedented detail in biological imaging

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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