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Nrf2 gene findings may offer therapeutic potential for sepsis treatment

Disruption of a single gene, Nrf2, plays a critical role in regulating the body's innate immune response to sepsis and septic shock, according to a study by a research team led by Shyam Biswal, PhD, at the Johns Hopkins Bloomberg School of Public Health.

4 Apr 2006

Custom made nanoparticles will transform cancer diagnosis and treatment

Researchers have developed "custom" nanoparticles that promise to provide a more targeted and effective way of delivering anticancer drugs than conventional medications or any of the earlier attempts to fight cancer with nanoparticles.

28 Mar 2006

Researchers find environmentally friendly ways to produce more Taxol

As the effective cancer-treatment drug Taxol enters its next generation, Michigan State University announces discoveries which point to both environmentally friendly ways to produce more Taxol, and ultimately innovations to produce a more potent second-generation drug.

28 Mar 2006

EntreMed announces new U.S. Patent - "Estrogenic Compounds as Anti-Mitotic Agents"

EntreMed has announced the issuance of U.S. Patent No. 7,012,070 covering methods of treatment for a broad range of indications with its lead clinical-stage compound, 2-methoxyestradiol (2ME2).

17 Mar 2006

FDA grants Cerexa fast track designation

Cerexa has announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for PPI-0903, a next-generation, broad-spectrum, cephalosporin antibiotic, for the treatment of complicated skin and skin structure infections (cSSSI) caused by methicillin-resistant Staphylococcus aureus (MRSA).

17 Mar 2006

Newly discovered genetic mechanism in poultry can provide more insights to complex diseases

Scientists from Uppsala University, the Swedish University of Agricultural Sciences, and the U.S. have identified a genetic mechanism that regulates growth in chickens.

13 Mar 2006

NHS surgeons left to "pick up the pieces" after poor surgery at private treatment centres

NHS surgeons are being left to "pick up the pieces" after poor surgery at private treatment centres, warns a senior doctor in the British Medical Journal.

13 Mar 2006

Next-generation drug development: risky and costly, but worth it

Generic drugs, which drive a $40 billion dollar generics industry expected to hit $60 billion by 2007, account for 53% of all prescriptions filled in the United States today.

6 Mar 2006

European electrosurgical devices - market analysis

Heightened awareness among both electrosurgical device companies and consumers about the potential spread of communicable diseases during surgery is encouraging the uptake of disposable electrosurgical devices.

16 Feb 2006

Flow technique - a quick and simple technique to characterize breast cancer cells

A quick and simple technique to characterize breast cancer cells may expedite and improve treatment decisions, researchers from the University of Illinois at Chicago report in the journal of Experimental and Molecular Pathology.

12 Feb 2006

Ice-templated fabrication shows promise for artificial bone

The next generation of artificial bone may rely on a few secrets from the sea. Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory have harnessed the way seawater freezes to develop a porous, scaffolding-like material that is four times stronger than material currently used in synthetic bone.

7 Feb 2006

Advanced Biomaterial Systems receives U.S. patent for mixing and dispensing apparatus

Advanced Biomaterial Systems, Inc. (ABS) has received U.S. patent 6,984,063 for an Apparatus for Mixing and Dispensing Components. This patent is a continuation of several patents which incorporate twistOR and Plexis technology.

23 Jan 2006

Novel compound stops brain cell degeneration in Alzheimer's disease

Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.

22 Jan 2006

Danger of resistance to malaria drug

The World Health Organization (WHO) has issued new guidelines concerning the use of the malaria drug Artemisinin.

22 Jan 2006

Having kids bad for mental well being

A new study in the U.S. says that being a parent may not be as fulfilling an experience as might be expected and in fact parenthood does not appear to offer any mental health benefit for the individuals involved.

16 Jan 2006

Importance of telomeres in preserving genome integrity and preventing cancer development

Researchers at the Salk Institute for Biological Studies discovered that cells co-opted the machinery that usually repairs broken strands of DNA to protect the integrity of chromosomes.

7 Dec 2005

New anti-clotting treatment

Volunteers at the Jack and Linda Gill Heart Institute at the University of Kentucky were the first ever to receive a new anti-clotting therapy.

7 Dec 2005

Skinphysical (skin damage test) launched in UK

A world-first test that assesses the damage people have done to their skin through sun exposure is being launched to the public at clinics throughout the UK.

26 Nov 2005

Analytical method to trace the lineage trees of cells

Some fundamental outstanding questions in science - "Where do stem cells originate?" "How does cancer develop?" "When do cell types split off from each other in the embryo?" - might be answered if scientists had a way to map the history of the body's cells going back to the fertilized egg.

30 Oct 2005

Chiron initiates Phase I/II study of an investigational cell culture-derived influenza vaccine

Cell culture-derived influenza vaccine (commonly referred to as "flu cell culture" vaccine) represents the next generation of influenza vaccine, both for annual vaccine production and for long-term pandemic preparedness.

26 Oct 2005