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Utah chemists devise new way to detect DNA damage

University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.

6 Nov 2015

Genetic reduction of AMPK enzyme can prevent or delay hearing loss

A mitochondrial defect is responsible for a type of human hereditary deafness that worsens over time and can lead to profound hearing loss.

6 Nov 2015

Circulating protein predicts risk of chronic kidney disease

Make room, cholesterol. A new disease marker is entering the medical lexicon: suPAR, or soluble urokinase-type plasminogen activator receptor.

6 Nov 2015

University of Leicester awarded BBSRC grant to explore three key areas that impact human health

The University of Leicester has been awarded over £1.5 million in order to advance knowledge and understanding in three key areas that impact on health.

5 Nov 2015

Janssen doses first patient in daratumumab clinical trial using Halozyme's ENHANZE technology

Halozyme Therapeutics, Inc. today announced that Janssen Biotech, Inc. has dosed the first patient in a clinical trial evaluating subcutaneous (SC) delivery of daratumumab with Halozyme's proprietary ENHANZE technology in multiple myeloma.

5 Nov 2015

Researchers successfully repair nerve cell damage in Alzheimer's dementia

In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Prof. Dr. Ulrike Müller and a team of French scientists have succeeded in largely "repairing" the nerve cell damage typical in this disease.

5 Nov 2015

Scientists create supercharged blood cell that may heal major wounds, block inflammation

Faculty of Medicine scientists have created a "Franken-platelet" - a supercharged blood cell - that might be capable of healing major wounds, busting clots or blocking inflammation.

5 Nov 2015

EndoGastric Solutions announces assignment of relative value units for new CPT code covering TIF procedure

EndoGastric Solutions® (EGS), a leader in incisionless procedural therapy for gastroesophageal reflux disease (GERD), today announced the Federal Register has posted coding and payment information specific to the new Current Procedural Terminology (CPT)® code covering the Transoral Incisionless Fundoplication (TIF®) procedure.

4 Nov 2015

Patients with Down syndrome face additional challenge of early-onset dementia

Individuals with Down syndrome who survive into adulthood face the additional challenge of early-onset dementia, in which toxic amyloid plaques build up in the brain. The condition is strikingly similar to Alzheimer's disease, and as new work led by researchers at the Lewis Katz School of Medicine at Temple University shows, dementia in Down syndrome involves defects in a regulatory enzyme known as γ-secretase activating protein (GSAP), which also happens to malfunction in Alzheimer's disease.

3 Nov 2015

TSRI scientists awarded NIH grant to investigate molecular machinery involved in cancer metastasis

Cancer metastasis occurs when tumor cells escape from a primary tumor, via the blood stream, and establish tumors in secondary locations. When the metastases are found in distant tissues and organs, doctors call this stage IV cancer, and the survival rate is low.

3 Nov 2015

PolyU researchers develop novel biosensor for measuring glucose level in saliva

Diabetic patients have to monitor blood glucose regularly and frequently, but conventional method of taking blood sample for measuring glucose level is painful. It is therefore important to develop high performance biological sensors for monitoring the glucose level at a reasonable cost.

3 Nov 2015

Inhibiting key enzyme pathways decreases inflammation and frailty in aged mice

Chronic inflammation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inflammation in human cells in culture dishes and decreases inflammation and frailty in aged mice.

3 Nov 2015

Salk scientists uncover enzyme responsible for suppressing deadly lung cancer

Scientists at the Salk Institute have uncovered a molecule whose mutation leads to the aggressive growth of a common and deadly type of lung cancer in humans.

3 Nov 2015

Griffith University uncovers first 3-D image of protein linked to cancer spread

Griffith University's Institute for Glycomics has made scientific history by determining the first three-dimensional image of a protein linked to the spread of cancer.

3 Nov 2015

Using smart phone to detect diabetes marker in saliva

With the participation of Mexican and international experts, the device will present immediate results and will be used for diagnosis within low-income populations.

31 Oct 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

New anti-malarial ‘biobricks' could pave way for easier, cost-effective production of artemisinin drug

Students from Trinity College Dublin have successfully created anti-malarial ‘biobricks', which could pave the way for easier and more cost-effective production of the key drug artemisinin.

31 Oct 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

University of Kansas professor recognized with MERIT Award

Emily Scott, professor of medicinal chemistry at the University of Kansas, has been recognized with a MERIT Award from the National Institutes of Health's National Institute of General Medical Sciences. It's a rare and important recognition -- researchers can receive them only once in a career.

30 Oct 2015

Study reports discovery of new class of DNA repair enzyme

This year's Nobel Prize in chemistry was given to three scientists who each focused on one piece of the DNA repair puzzle. Now a new study, reported online Oct. 28 in the journal Nature, reports the discovery of a new class of DNA repair enzyme.

30 Oct 2015

Enzyme News and Research

Utah chemists devise new way to detect DNA damage

Genetic reduction of AMPK enzyme can prevent or delay hearing loss

Circulating protein predicts risk of chronic kidney disease

University of Leicester awarded BBSRC grant to explore three key areas that impact human health

Janssen doses first patient in daratumumab clinical trial using Halozyme's ENHANZE technology

Researchers successfully repair nerve cell damage in Alzheimer's dementia

Scientists create supercharged blood cell that may heal major wounds, block inflammation

EndoGastric Solutions announces assignment of relative value units for new CPT code covering TIF procedure

Patients with Down syndrome face additional challenge of early-onset dementia

TSRI scientists awarded NIH grant to investigate molecular machinery involved in cancer metastasis

PolyU researchers develop novel biosensor for measuring glucose level in saliva

Inhibiting key enzyme pathways decreases inflammation and frailty in aged mice

Salk scientists uncover enzyme responsible for suppressing deadly lung cancer

Griffith University uncovers first 3-D image of protein linked to cancer spread

Using smart phone to detect diabetes marker in saliva

Key protein controls stem cell properties that could make them useful in regenerative medicine

New anti-malarial ‘biobricks' could pave way for easier, cost-effective production of artemisinin drug

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

University of Kansas professor recognized with MERIT Award

Study reports discovery of new class of DNA repair enzyme

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