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Scientists crack crystal structure of entire ZIKV NS5 protein

Zika virus (ZIKV), which causes Zika virus disease, is spread to people primarily through the bite of an infected Aedes aegypti or Aedes albopictus mosquito. An infected pregnant woman can pass ZIKV to her fetus during pregnancy or around the time of birth. Sex is yet another way for infected persons to transmit ZIKV to others.

27 Mar 2017

Study identifies correlations between gene data and brain activity during memory processing

Researchers have identified more than 100 genes important for memory in people. The study is the first to identify correlations between gene data and brain activity during memory processing, providing a new window into human memory.

27 Mar 2017

Neurosurgeons must advance strategies and adapt new ways to thrive in evolving healthcare industry

Neurosurgeons hoping to successfully navigate the rapidly changing healthcare industry must advance their strategies and adapt new ways of thinking in order to continue to thrive in an evolving environment.

25 Mar 2017

Articles review current landscape of primary care innovation

Primary care is "first-contact, continuous, comprehensive, and coordinated care provided to populations undifferentiated by gender, disease, or organ system.

25 Mar 2017

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.

25 Mar 2017

One-shot vaccine passes key preclinical test in newborn monkey models

Newborns are highly vulnerable to infections and don't respond optimally to most vaccines because their young immune systems typically mount weak antibody responses.

24 Mar 2017

Research suggests way to reverse age-related and radiation-induced DNA damage

DNA repair is essential for cell vitality, cell survival and cancer prevention, yet cells' ability to patch up damaged DNA declines with age for reasons not fully understood.

24 Mar 2017

Brain makes new connections in blind people to enhance compensatory abilities

The brains of those who are born blind make new connections in the absence of visual information, resulting in enhanced, compensatory abilities such as a heightened sense of hearing, smell and touch, as well as cognitive functions (such as memory and language) according to a new study led by Massachusetts Eye and Ear researchers.

23 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

Discovery about retinal zinc may show new way to protect, regenerate optic nerve in glaucoma patients

Connecting pieces of information by finding a common thread often takes glaucoma researchers in unexpected directions.

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Optical imaging tool could help track the brain's circulatory response to acute pain in adults, infants

Functional near-infrared spectroscopy (fNIRS), an optical imaging tool for monitoring of regional blood flow and tissue oxygenation, is being explored as a way to track the brain's response to acute pain in adults and infants.

23 Mar 2017

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

22 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

New guidelines to assess older people who have fallen found to be safe and cost-effective

Guidelines to help paramedics make the right decision for older people who have fallen are safe, cost-effective and help reduce further 999 calls, according to new research led by a team at Swansea University Medical School.

22 Mar 2017

Study evaluates screening and treatment for subclinical thyroid disease during pregnancy

Observational studies over the past 30 years suggest that subclinical thyroid disease during pregnancy may be associated with adverse outcomes, including a lower-than-normal IQ in offspring.

22 Mar 2017

FARE announces recipients of 2017 Investigator in Food Allergy Awards

Food Allergy Research & Education, the world's largest private source of funding for food allergy research, is pleased to announce the recipients of the 2017 FARE Investigator in Food Allergy Awards after an extraordinarily competitive review process, with more than two dozen researchers submitting high-quality proposals.

22 Mar 2017

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Translational Therapeutics at the Perelman School of Medicine at the University of Pennsylvania, has received the 2017 Scientific Innovations Award from the Chicago-based Brain Research Foundation, which supports research for preventing and treating neurological diseases.

22 Mar 2017

Study may signal major shift in understanding of how the cerebellum encodes information

It's the part of the brain that makes sure you cannot tickle yourself. The cerebellum, an apple-sized region near the base of the skull, senses that your own fingers are the ones trying to tickle, and cancels your usual response.

21 Mar 2017

Structured interviews may be effective in identifying women at risk of postpartum depression

For non-depressed, pregnant women with histories of major depressive disorder, preventive treatment with antidepressants may not necessarily protect against postpartum depression, according to new UCLA research.

21 Mar 2017

Medical School News and Research

Scientists crack crystal structure of entire ZIKV NS5 protein

Study identifies correlations between gene data and brain activity during memory processing

Neurosurgeons must advance strategies and adapt new ways to thrive in evolving healthcare industry

Articles review current landscape of primary care innovation

Major grant funds research effort that seeks to understand complexity of invasive cancer

One-shot vaccine passes key preclinical test in newborn monkey models

Research suggests way to reverse age-related and radiation-induced DNA damage

Brain makes new connections in blind people to enhance compensatory abilities

Genome sequencing approach opens door to therapy options for rare, neglected cancers

Discovery about retinal zinc may show new way to protect, regenerate optic nerve in glaucoma patients

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Optical imaging tool could help track the brain's circulatory response to acute pain in adults, infants

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Heroin use linked to epigenetic alterations in the brain

New guidelines to assess older people who have fallen found to be safe and cost-effective

Study evaluates screening and treatment for subclinical thyroid disease during pregnancy

FARE announces recipients of 2017 Investigator in Food Allergy Awards

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

Study may signal major shift in understanding of how the cerebellum encodes information

Structured interviews may be effective in identifying women at risk of postpartum depression

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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