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ICUs become a ‘delirium factory’ for COVID patients

Doctors are fighting not only to save lives from COVID-19, but also to protect patients' brains.

3 Jun 2020

Scientists map how SARS-CoV-2 infects the airways

Now, in a significant scientific study, a team of researchers at the University of North Carolina Health Care (UNC) have mapped how SARS-CoV-2, the virus that causes the coronavirus disease (COVID-19), infects the nasal cavity, the airways, and down to the lungs.

3 Jun 2020

Cone snail venom produces new type of insulin

Diabetes is a global health issue affecting millions. In 2014, there were 422 million diabetics, compared to 108 million in 1989. The condition can be treated with diet, physical activity, medicines like synthetic insulin injections, and regular screening.

3 Jun 2020

Does smoking increase COVID-19 risk?

The COVID-19 pandemic continues to smolder and smoke in many parts of the world, with over 100,000 cases, and more than 3,000 deaths reported every day. Many factors are responsible for the higher risk of infection in certain specific population subgroups are known.

2 Jun 2020

SARS-CoV-2 can adversely affect cardiac cells and heart function

A research group from Germany demonstrated a direct toxic effect of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on cardiac cells in their paper published on the bioRxiv* preprint server. The finding warrants an in-depth analysis of cardiac tissue in certain coronavirus disease (COVID-19) patients, as well as close monitoring for any direct cardiomyocyte injury.

2 Jun 2020

Could the next pandemic be 100 times worse than COVID-19?

As the world tries to cope with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease (COVID-19), Dr. Michael Herschel Greger has claimed that worse could be yet to come. The American nutrition expert has claimed in his latest book that the next pandemic could be due to virus emanating from poultry farms.

2 Jun 2020

A cytokine pattern that predicts adverse outcomes in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports the discovery of a predictive pattern of cytokines in COVID-19 infection that could guide clinical management if validated.

2 Jun 2020

Study: High estrogen levels may influence alcohol use disorder

A new study from researchers at the University of Illinois at Chicago shows that high estrogen levels may make alcohol more rewarding to female mice.

2 Jun 2020

SARS-CoV-2 emergence could be due to genetic selection and recombination

Researchers have found that genetic selection and recombination could be behind the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that leads to acute respiratory distress syndrome (ARDS) or COVID-19 disease. This research could explain COVID-19 pandemic and its emergence. The study titled, “Emergence of SARS-CoV-2 through recombination and strong purifying selection,” was published in the journal Science Advances.

1 Jun 2020

Study maps novel coronavirus infection in cells of nasal cavity, airway and lungs

In a major scientific study published in the journal Cell, scientists at the UNC School of Medicine and the UNC Gillings School of Global Public Health have characterized the specific ways in which SARS-CoV-2 – the coronavirus that causes COVID-19 – infects the nasal cavity to a great degree – replicating specific cell types – and infects and replicates progressively less well in cells lower down the respiratory tract, including the lungs.

1 Jun 2020

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

A research group from the University of Texas in Austin described a high-yield production of a stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) that may accelerate the development of vaccines and diagnostic tests. This methodological 'tour de force' paper is currently available on the bioRxiv* preprint server.

1 Jun 2020

Cone snail insulin research could jumpstart the development of better diabetes treatments

Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world's smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails.

1 Jun 2020

No specific COVID-19-linked lesions found despite extensive organ injury

A recent paper published online on the preprint server medRxiv in May 2020 reports autopsy results on COVID-19 patients. The paper concludes that there were no specific hallmark lesions of COVID-19 in any of the many organs found to be injured by the infection in patients who died of the disease.

1 Jun 2020

Anesthetic drug Ketamine uses serotonin receptors to relieve depression

Ketamine is a drug used to induce general anesthesia. It has also been found to act rapidly to relieve depression that has failed to respond to two other rounds of medication. A new study published in the journal Translational Psychiatry in May 2020 reports the mechanism of action of the drug, which was hitherto unknown. This could help find new ways to treat this debilitating and sometimes fatal condition.

31 May 2020

How COVID-19 affects the nervous system

A new paper published in the journal JAMA Neurology in May 2020 discusses the presentation and complications of COVID-19 with respect to the nervous system.

31 May 2020

Researchers show how ketamine fights difficult-to-treat depression

The anaesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression.

31 May 2020

Neanderthal gene in women boosts infertility

It is still unclear why some women go into labor for long periods, and some face a high risk of childbirth. Also, some women fall pregnant quickly, while others may take years before they conceive. The answer may be due to a gene inherited from the Neanderthals, an extinct species or subspecies of archaic humans who lived in Eurasia until about 40,000 years ago.

31 May 2020