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Serotonin promotes beta cell expansion during pregnancy, offers possible cure for type 1 diabetes

Researchers funded by JDRF have discovered that the hormone, serotonin, may be involved in the increase of insulin-producing beta cells during pregnancy.

29 Jun 2010

Cells in immune system react to stomach ulcer bacterium Helicobacter pylori, identify researchers

Researchers have identified cells in the immune system that react to the stomach ulcer bacterium Helicobacter pylori, one of the risk factors for the development of stomach cancer. This discovery could lead to faster diagnosis and treatment as well as a better prognosis for patients with stomach cancer, reveals a thesis from the University of Gothenburg, Sweden.

28 Jun 2010

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the mother's diet early in pregnancy, according to new findings of an international team led by researchers at UCSF.

28 Jun 2010

Gastric bypass surgery improves insulin sensitivity in Type 2 diabetes patients

Gastric bypass surgery improves Type 2 diabetes by other mechanisms in addition to weight loss and does so better than a low-calorie diet despite achieving equal weight loss, a new study finds. The results will be presented Monday at The Endocrine Society's 92nd Annual Meeting in San Diego.

21 Jun 2010

Ancient circadian clock regulates insulin production

The pancreas has its own molecular clock. Now, for the first time, a Northwestern University study has shown this ancient circadian clock regulates the production of insulin. If the clock is faulty, the result is diabetes.

19 Jun 2010

S*BIO completes enrollment in SB1518 JAK2 inhibitor Phase 2 clinical trials for myelofibrosis

S*BIO Pte Ltd today announced that it has completed enrollment of patients in two separate Phase 2 clinical trials for its potent and orally-active JAK2 inhibitor SB1518 at multiple clinical sites in the U.S. and Australia for the treatment of myelofibrosis (MF).

9 Jun 2010

Vitiligo associated with genes variations linked to body's immune response

Scientists including researchers from the University of Florida have discovered additional evidence that generalized vitiligo - a disease that typically causes patches of white skin on the face, neck and extremities that pop star Michael Jackson may have experienced - is associated with slight variations in genes that play a role in the body's natural defenses.

8 Jun 2010

Gene variant linked to ability of Tibetans to cope with low-oxygen conditions identified

A new study pinpoints the genetic changes that enable Tibetans to thrive at altitudes where others get sick.

8 Jun 2010

Researchers decipher how mast cells set immune defense on right track

In the event of an infection, the immune system releases messenger substances. These molecules can either activate immune cells to defeat invading pathogens, or inhibit them to prevent an excessive immune reaction. For this, the immune system has to decide very quickly what mixture of activating and inhibiting messenger molecules leads to a successful defence.

8 Jun 2010

Vitiligo is associated with variations in genes that play role in body's natural defenses: Scientists

Scientists including researchers from the University of Florida have discovered additional evidence that generalized vitiligo — a disease that typically causes patches of white skin on the face, neck and extremities that pop star Michael Jackson may have experienced — is associated with slight variations in genes that play a role in the body's natural defenses.

7 Jun 2010

EMBL scientists identify two small RNA molecules that ensure red blood cell production

Red blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second - even more in response to challenges like severe blood loss. In a study published today in the Journal of Experimental Medicine, scientists at the European Molecular Biology Laboratory in Monterotondo, Italy, and EMBL's European Bioinformatics Institute in Hinxton, UK, have identified two small RNA molecules which ensure that enough red blood cells are produced efficiently, by fine-tuning a number of different genes involved in this process.

2 Jun 2010

Postdoctoral scientists receive NYSCF-Druckenmiller Fellowship award

The New York Stem Cell Foundation (NYSCF) today announced the award of eight new NYSCF-Druckenmiller Fellows. These postdoctoral scientists join 15 accomplished stem cell researchers from leading institutions who have been supported by the program since 2006. NYSCF has awarded 23 fellowships to date.

2 Jun 2010

OHSU partners with UO, Harvard to expedite research into compounds that may prevent Fanconi anemia

Oregon Health & Science University is partnering with the University of Oregon and Harvard Medical School to expedite basic science research into new and existing drugs and compounds that may prevent the complications associated with Fanconi anemia, an inherited condition that can lead to bone marrow failure and cancer.

28 May 2010

UCSF scientists discover new stem cell in developing human brain

UCSF scientists have discovered a new stem cell in the developing human brain. The cell produces nerve cells that help form the neocortex - the site of higher cognitive function -- and likely accounts for the dramatic expansion of the region in the lineages that lead to man, the researchers say.

26 May 2010

Researchers determine critical role of bone marrow cells in fighting respiratory viruses

Researchers at Mount Sinai School of Medicine for the first time have determined that bone marrow cells play a critical role in fighting respiratory viruses, making the bone marrow a potential therapeutic target, especially in people with compromised immune systems. They have found that during infections of the respiratory tract, cells produced by the bone marrow are instructed by proteins to migrate to the lungs to help fight infection. The data are published in the current issue of Cell Host & Microbe.

25 May 2010

Researchers discover biological pathway signature of ccRCC

By examining expression of every human gene in clear cell renal cell carcinoma compared to normal kidney cells, researchers at Mayo Clinic's campus in Florida have discovered gene signatures they say explain much of the biology of this common and difficult-to-treat kidney cancer.

19 May 2010

Benefits outweigh risks in myeloablative therapy for children with high-risk neuroblastoma

Neuroblastoma is among the most common of childhood cancers and fortunately, some children will get better spontaneously. Yet for children with high-risk disease the outlook is poor: more than half will relapse despite chemotherapy.

12 May 2010

People with family history of diabetes gain more weight

In the first study of its type, Australian researchers have shown that healthy people with a genetic predisposition to Type 2 diabetes gain more weight overeating over the short term than their non-genetically-prone counterparts.

11 May 2010

Aastrom Biosciences reports third quarter 2010 FY results

Aastrom Biosciences, Inc., the leading developer of autologous cellular therapies for the treatment of severe cardiovascular diseases, today reported financial results for its third fiscal quarter ended March 31, 2010, and also announced progress in its late-stage clinical development programs and corporate operations.

11 May 2010

UC San Diego researchers discover potential new treatment for familial adenomatous polyposis

A team of University of California, San Diego School of Medicine researchers has discovered that common intestinal bacteria appear to promote tumor growths in genetically susceptible mice, but that tumorigenesis can be suppressed if the mice are exposed to an inhibiting protein enzyme.

10 May 2010

Cell Production News and Research

Serotonin promotes beta cell expansion during pregnancy, offers possible cure for type 1 diabetes

Cells in immune system react to stomach ulcer bacterium Helicobacter pylori, identify researchers

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

Gastric bypass surgery improves insulin sensitivity in Type 2 diabetes patients

Ancient circadian clock regulates insulin production

S*BIO completes enrollment in SB1518 JAK2 inhibitor Phase 2 clinical trials for myelofibrosis

Vitiligo associated with genes variations linked to body's immune response

Gene variant linked to ability of Tibetans to cope with low-oxygen conditions identified

Researchers decipher how mast cells set immune defense on right track

Vitiligo is associated with variations in genes that play role in body's natural defenses: Scientists

EMBL scientists identify two small RNA molecules that ensure red blood cell production

Postdoctoral scientists receive NYSCF-Druckenmiller Fellowship award

OHSU partners with UO, Harvard to expedite research into compounds that may prevent Fanconi anemia

UCSF scientists discover new stem cell in developing human brain

Researchers determine critical role of bone marrow cells in fighting respiratory viruses

Researchers discover biological pathway signature of ccRCC

Benefits outweigh risks in myeloablative therapy for children with high-risk neuroblastoma

People with family history of diabetes gain more weight

Aastrom Biosciences reports third quarter 2010 FY results

UC San Diego researchers discover potential new treatment for familial adenomatous polyposis

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