DNA Damage News and Research

RSS

Scientists discover lung cell that can hustle to repair its damaged DNA and survive influenza

Scientists at Duke University have identified one kind of lung cell that can hustle to repair its damaged DNA and survive an attack of the influenza A virus while other kinds of cells around it die in droves.

30 Jul 2019

Discovery could open door to new therapies for Parkinson's, other brain diseases

A small protein previously associated with cell dysfunction and death in fact serves a critical function in repairing breaks in DNA, according to new research led by scientists at Oregon Health & Science University.

29 Jul 2019

Unexpected discovery could improve treatment of cancer, other diseases

EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.

23 Jul 2019

Scientists identify new way to target bottleneck for cancer cell growth

The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts.

23 Jul 2019

UV-DDB protein scouts DNA damage and oversees repair

In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a glimpse of how one protein in particular keeps DNA damage in check.

22 Jul 2019

Slug serves as 'command central' for determining breast stem cell health

A new study published in Cell Reports found that a transcription factor called Slug serves as 'command central' for determining breast stem cell health, regulating both stem cell activity and repair of DNA damage.

17 Jul 2019

Experts discuss 5G health risks as network switches on in the UK

As the 5G mobile network launches in some UK cities, experts discuss whether there is any reliable evidence to suggest people should be worried.

15 Jul 2019

Research sheds light on sun-induced DNA damage and repair

It is a well known fact that the sun’s ultraviolet rays can damage the skin. Now, a new study sheds light on what happens after DNA damage occurs, and how the body initiates repair.

15 Jul 2019

Age-related risk of Alzheimer's explained at the molecular level

Studies have shown that Alzheimer’s disease (AD) incidence increases with age. This association with age also correlates with deposits of abnormal tau protein in the brain found a new study.

9 Jul 2019

Mechanism Behind Low Cancer Occurrence In Bats Signals Potential Treatment Strategies For Humans

Cancer is a leading cause of death in aging populations. Despite decades of research, cancer treatments are still inefficient and have unacceptable side effects that continue to prompt an urgent need for new approaches to prevention and treatment.

4 Jul 2019

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

More than 60 years ago, British physician Denis Parsons Burkitt and his associates achieved one of the signal successes in cancer medicine when they cured children in sub-Saharan Africa with a form of lymphoma by treating them with high doses of the chemotherapy drug cyclophosphamide.

2 Jul 2019

Study uncovers new way to identify driver genes important for cancer progression

Until now, researchers believed recurrent mutations (hotspot mutations) in cancer tumors were the important mutations (driver mutations) that promoted cancer progression.

29 Jun 2019

Immune system could be blamed for ineffectiveness of high-dose radiation against lung cancer

When it comes to using radiation against lung cancer, preliminary clinical studies were pretty clear: More is better.

27 Jun 2019

Study shows how gastric stem cells fight colonizing bacteria

Stem cells are not only key players in tissue regeneration, they are also capable of taking direct action against bacteria.

25 Jun 2019

Long-term cryopreservation of semen does not affect future clinical outcomes

Despite a time limit imposed in many countries on the freeze-storage of sperm, a new study from China has found that the long-term cryopreservation of semen in a sperm bank does not affect future clinical outcomes

25 Jun 2019

New spectroscopic approach investigates difficult-to-observe protein structures

Combining research-oriented teaching and interdisciplinary collaboration pays off: Researchers at the University of Konstanz develop a novel spectroscopic approach to investigate hitherto difficult-to-observe protein structures.

19 Jun 2019

Researchers identify effective drug combinations for malignant brain tumor in mice

Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it is the other way round: when trying to find new treatments, scientists find key information on cancer biology.

14 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Human body is a mosaic pattern of DNA mutations, say researchers

Researchers have discovered that the cells of the human body aren’t clones of a single DNA sequence, but are actually a mosaic of mutations.

7 Jun 2019

Early genome catastrophes can lead to development of lung cancer in non-smokers

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers.

31 May 2019