Omicron News and Research

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A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

In a recent study posted to the medRxiv* preprint server, researchers in the United States assessed the efficiency of protection mediated by antibodies against symptomatic coronavirus disease 2019 (COVID-19) at low serum-neutralizing titers.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

A study of Moderna's COVID vaccine in children aged 6 months to 5 years

In a recent study published in the New England Journal of Medicine, researchers presented the findings of the ongoing KidCOVE trial in the United States (US).

23 Oct 2022

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Researchers evaluate SARS-CoV-2 vaccine-induced immune responses in SARS survivors.

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

Antiseptic chewing gum reduces SARS-CoV-2 viral load in exhaled air

A recent study determined the effectiveness of antiviral chewing gum in reducing oral viral load in the exhaled air of COVID-19 patients.

23 Oct 2022

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

Researchers investigated the association between two or three doses of the messenger ribonucleic acid (mRNA) COVID-19 vaccine and viral loads and symptoms during infections with different SARS-CoV-2 variants.

23 Oct 2022

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Researchers demonstrated the structural basis of how the receptor-binding domain nested Omicron mutations have adapted to mouse angiotensin-converting enzyme 2 rather than human ACE2.

22 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Researchers conducted a nationwide study in Denmark to assess the public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2.

22 Oct 2022

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

In a recent study posted to the medRxiv* preprint server, University of Arizona researchers assessed the relationship between antibody responses and analgesic usage after coronavirus disease 2019 (COVID-19) vaccination.

20 Oct 2022

Are pediatric COVID-19 samples less infectious?

Researchers determine whether children are less hospitable to SARS-CoV-2 and, as a result, pose a lower risk of a viral spread than adults.

20 Oct 2022

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

In a recent study posted to the bioRxiv* preprint server, researchers at Ohio State University and the University of Texas Medical Branch assessed the underlying mechanisms involved in the fusogenicity and endosomal entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

20 Oct 2022

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

A recent study investigates poorer vaccine responses observed in the elderly following receipt of a COVID-19 booster vaccination dose.

19 Oct 2022

SARS-CoV-2 transmission from infected owner to pet rats

SARS-CoV-2 Omicron transmission from a symptomatically infected individual to two domestic rats.

19 Oct 2022

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

Differential effects of SARS-CoV-2 variants on children and adolescents

A recent Emerging Infectious Diseases journal study evaluated whether specific SARS-CoV-2 variants were linked with different clinical manifestations in children and adolescents.

19 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Study reveals high level of hybrid immunity in general Swiss population

A recent study covering the general Swiss population has evaluated the development of hybrid immunity during the pandemic wave dominated by the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Oct 2022

Omicron News and Research

A novel approach for viral genomic surveillance

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

A study of Moderna's COVID vaccine in children aged 6 months to 5 years

Immune response in SARS-CoV-1 survivors after COVID-19 vaccination

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Antiseptic chewing gum reduces SARS-CoV-2 viral load in exhaled air

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

Are pediatric COVID-19 samples less infectious?

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

SARS-CoV-2 transmission from infected owner to pet rats

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Differential effects of SARS-CoV-2 variants on children and adolescents

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

Study reveals high level of hybrid immunity in general Swiss population

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