Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Researchers clarify cellular processes related to radiation resistance of pancreatic cancer cells

Pancreatic cancer is one of the deadliest cancer subtypes not just because it is difficult to diagnose early, but because it is inherently resistant to chemotherapy and radiotherapy.

8 Jun 2021

Researchers develop promising stem cell therapy to treat type 1 diabetes

Type 1 diabetes, which arises when the pancreas doesn't create enough insulin to control levels of glucose in the blood, is a disease that currently has no cure and is difficult for most patients to manage.

8 Jun 2021

Measuring how patterns of gene expression change in children may help predict T1D progression

Type 1 diabetes (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys healthy pancreatic islet β cells, resulting in a lack of insulin.

7 Jun 2021

Weight loss drug Wegovy approved by FDA

The U.S. Food and Drug Administration (FDA) has approved Wegovy (semaglutide) injection (2.4 mg once weekly) as a chronic weight management treatment in obese or overweight adults with a weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), when used along with calorie restriction and physical activity. Wegovy, is a more potent version of Novo Nordisk's diabetes drug semaglutide.

4 Jun 2021

Eating at least two servings of fruit per day reduces diabetes risk by 36%

Researchers at Edith Cowan University revealed that people who consumed at least two servings of fruit per day had higher measures of insulin sensitivity than those who ate less than a half serving. The study, published in the Journal of Clinical Endocrinology and Metabolism, showed that a healthy diet including whole fruits, but not fruit juice, may play a role in mitigating type 2 diabetes risk.

4 Jun 2021

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

3 Jun 2021

AMSBIO's custom lentivectors for labeling organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

Cancer risk increases with the number of cigarettes smoked per day, confirms study

Today, in advance of World No Tobacco Day, The Daffodil Centre released an Australian first study, with findings showing tobacco smoking significantly increased the risk of 12 types of cancer and that 1-in-7 current smokers will get lung cancer in their lifetime.

29 May 2021

Gestational diabetes during pregnancy can increase risk of type-1 and type-2 diabetes

A 23 year study being presented at the 23rd European Congress of Endocrinology (e-ECE 2021), on Monday 24 May 2021 at 14:40 CET, has found that women who experience gestational diabetes (GDM) when they are pregnant, are more prone to developing type-1 and type-2 diabetes later in life.

24 May 2021

Facets of SARS-CoV-2 infection and animal models

A new study in the journal Frontiers in Cell and Developmental Biology discusses the ribonucleic acid (RNA) genome of the virus, and the mechanisms by which it establishes infection within the host cell. The researchers also summarize the development of animal models of COVID-19, which will both help understand the clinical features of the illness, and indicate new approaches for the treatment of the infection.

21 May 2021

Asthma patients can benefit from type 2 diabetes medication

Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.

21 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Approval is the most significant advancement in the treatment of chronic kidney disease in more than 20 years. In DAPA-CKD Phase III trial, Farxiga demonstrated unprecedented reduction in the risk of the composite of worsening of renal function, end-stage kidney disease and cardiovascular or renal death.

From AstraZeneca 14 May 2021

Keyhole surgery for liver cancer results in better outcomes and quality of life

Those who had tumors removed from their livers with keyhole surgery had fewer complications, a better quality of life and similar long-term oncologic outcomes, a new PhD thesis shows.

10 May 2021

Obesity measures are associated with higher risk for 10 cancers

Obesity increases the risk of developing 10 of the most common cancers, regardless of how it is measured, according to a study of more than 400,000 adults in the UK, being presented at The European Congress on Obesity (ECO) held online this year, with central fatness (larger waist and hips) and general obesity (body mass index [BMI] and body fat percentage) associated with similar estimates of cancer risk.

10 May 2021

Novel method provides faster and more precise diagnostics in histopathology

Histology is the study of biological tissues at a microscopic level. Also called microscopic anatomy, histology is widely used to provide diagnosis of cancer and other diseases.

30 Apr 2021

Simple device can reduce swelling after kidney transplantation

In a published study, a team from Lawson Health Research Institute has found that a simple device can reduce swelling after kidney transplantation.

29 Apr 2021

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

A Ludwig Cancer Research study has identified a previously unrecognized mechanism by which cancer cells of a relatively benign subtype of pancreatic tumors methodically revert-or "de-differentiate"-to a progenitor, or immature, state of cellular development to spawn highly aggressive tumors that are capable of metastasis to the liver and lymph nodes.

29 Apr 2021

Researchers develop first 3D organoid models of the pancreas from human stem cells

This year, more than 60,000 adults in the United States will be diagnosed with pancreatic cancer and, statistically, as few as 10 percent will survive five years after diagnosis, according to the American Cancer Society.

28 Apr 2021

Topical therapy can help safely reduce side effect of cancer treatment

Patients with advanced colorectal cancer may be spared from a toxic side effect caused by a type of targeted therapy used to treat the cancer with the help of another drug normally used to treat melanoma, according to a study led by researchers at the UCLA Jonsson Comprehensive Cancer Center and Memorial Sloan Kettering Cancer Center.