Protein Synthesis News and Research

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Bad news for disease-causing bacteria!

Scientists have what could be some very bad news for disease-causing bacteria. All three major classes of antibiotics that kill infectious bacteria do so in part by ramping up the production of harmful free radicals, researchers report in the September 7, 2007, issue of Cell, a publication of Cell Press.

10 Sep 2007

New way to burn off calories

A new study in the September issue of Cell Metabolism, a publication of Cell Press, points to a new method for burning off all those irresistible extra calories—by turning on an energy-draining, but otherwise futile, cycle of protein synthesis and breakdown.

5 Sep 2007

New targets for antibiotics

University of Illinois at Chicago researchers have identified new sites on the bacterial cell's protein-making machinery where antibiotics can be delivered to treat infections.

30 Aug 2007

Study looks at large burns

Large burns can trigger cardiac problems and enhanced inflammatory and hypermetabolic responses in patients, a study in the online open access journal Critical Care suggests.

24 Aug 2007

New Cockayne syndrome discovery

Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have shown that the genetic defect that causes Cockayne Syndrome affects a key function of the cell – the transcription of genes coding for ribosomal RNA.

21 Aug 2007

Children need a certain amount of fat in their diet

Parents should think twice before offering a low-fat menu to youngsters, despite concerns over obesity.

17 Aug 2007

Protein-rich foods slow the deterioration of elderly people's muscles

Scientists at the University of Texas Medical Branch at Galveston have good news for people who want to stay strong in their old age: older bodies are just as good as young ones at turning protein-rich food into muscle.

9 Aug 2007

New view on role of protein synthesis in memory formation

New research from the University of Illinois challenges the premise that the brain must build new proteins in response to an experience for that experience to be recorded in long-term memory.

27 Jul 2007

Scientists clarify molecular basis of interferon action

Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans.

20 Jul 2007

Protein synthesis without amino acids

Usually, the synthesis of short protein chains (polypeptides) begins with the production of their components, the amino acids.

20 Jul 2007

Researchers discover how microRNAs control protein synthesis

While most RNAs work to create, package, and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression.

10 Jul 2007

More muscle for the argument to give up smoking

Researchers at The University of Nottingham have got more bad news for smokers. Not only does it cause cancer, heart attacks and strokes but smokers will also lose more muscle mass in old age than a non-smoker. The effect of this predisposes smokers to an accelerated decline in physical function and loss of independence.

9 Jul 2007

New compound kills fungal pathogens

A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory (EMBL) outstation in Grenoble, France.

23 Jun 2007

Anacor finds novel mechanism for lead anti-fungal drug, AN2690

Anacor Pharmaceuticals, a privately held pharmaceutical company, has announced that the journal Science will publish results of research that details how AN2690, the company's lead clinical candidate, kills fungal cells by interfering with synthesis of a specific protein required for fungal growth.

23 Jun 2007

Researchers find new mechanism of action of the anti-cancer drug sorafenib

Virginia Commonwealth University Massey Cancer Center researchers have uncovered a new mechanism of action of the anti-cancer drug sorafenib, which could stimulate the development of novel regimens in which it is combined with other molecularly targeted agents for patients with blood cancers and solid tumors.

15 Jun 2007

Exercise helps maintain muscle in elderly

Why do older people tend to lose muscle mass and grow frail?

1 Jun 2007

New findings on microRNAs

Over 30% of our genes are under the control of small molecules called microRNAs.

17 May 2007

Researchers discover how antibiotic linezolid inhibits bacterial growth

Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth.

11 May 2007

Extended bed rest leads to substantial muscle deterioration in older adults

Extended bed rest – often necessary during hospitalization – leads to a substantial amount of muscle deterioration in older adults, researchers at the University of Arkansas for Medical Sciences (UAMS) report in the April 25 issue of the Journal of the American Medical Association .

25 Apr 2007