Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Kraepelin distinctions back in favor

Modern statistical methods support Kraepelin’s original distinction between schizophrenia and bipolar disorder, but not the more recent schizoaffective disorder category, say researchers.

11 Oct 2013

Antisocial path to violence in psychosis

People are at particular risk for violent behavior during a first episode of psychosis if they have displayed antisocial behavior since childhood, show findings from the UK National EDEN Study.

10 Oct 2013

Self-management toolkit helps relatives of people with new-onset psychosis

Findings from a recent real-world clinical study indicate that relatives of people with recent-onset psychosis benefit from supported self-management interventions to help with outcomes such as distress and negative feelings around caregiving.

9 Oct 2013

UCLA investigates high rates of schizophrenia in people with 22q11.2 deletion syndrome

UCLA has joined an international consortium to investigate the high rates of schizophrenia and other neuropsychiatric disorders in those who are affected with Chromosome 22q11.2 deletion syndrome, a disorder caused by the deletion of a small piece of chromosome number 22.

9 Oct 2013

Parkinsonism predicts schizophrenia cognitive course

Parkinsonism is common in patients with first-episode psychosis and is predictive of cognitive impairment, say researchers.

3 Oct 2013

Affective dimensions aid bipolar disorder diagnosis

Measuring affective dimensions can help clinicians diagnose bipolar disorder in patients with first-episode psychosis, researchers report.

3 Oct 2013

Adolescent psychotic experiences lack uniformity

Psychotic experiences in adolescence appear to be quite distinct and vary widely from individual to individual, study findings indicate.

3 Oct 2013

Multiple aspects to severe bipolar mixed states

Researchers have identified four subgroups of severe bipolar mixed states, characterized by distinct symptomatologic presentations.

1 Oct 2013

Cogstate test shows effective treatment option for schizophrenia

Medical technology company Cogstate continues to strengthen its position as an essential partner for measuring cognition in important studies around the world, with results from a schizophrenia study using Cogstate's test published in a major scientific journal.

27 Sep 2013

Drug misuse predicts protracted hospital stay for schizophrenia patients

Patients hospitalized with schizophrenia have more severe symptoms and spend longer in hospital if they have a concurrent substance use disorder, report researchers.

26 Sep 2013

T. gondii antibodies implicated in mania

Infection with Toxoplasma gondii may confer an increased risk for mania, say researchers.

26 Sep 2013

Early intermodality dysfunction predicts schizophrenia risk

Researchers have found abnormalities in the way infants of parents with schizophrenia perceive the way they move and how this relates to vision, touch, hearing, and orientation.

25 Sep 2013

Researchers identify molecular pathway linking ICU ventilation to brain damage

At least 30 percent of patients in intensive care units (ICUs) suffer some form of mental dysfunction as reflected in anxiety, depression, and especially delirium. In mechanically-ventilated ICU patients, the incidence of delirium is particularly high, about 80 percent, and may be due in part to damage in the hippocampus, though how ventilation is increasing the risk of damage and mental impairment has remained elusive.

25 Sep 2013

Prefrontal glutamate abnormalities confined to established psychosis

Abnormalities in glutamate and glutamine levels in the prefrontal cortex are only present in patients with chronic schizophrenia, say researchers.

24 Sep 2013

Inflammation tracks mania course

Markers of inflammation are elevated in patients who are hospitalized for acute mania, a study shows.

24 Sep 2013

Adolescents with psychosis face long treatment delays

Adolescents have a duration of untreated psychosis that is approximately twice that seen in adults, UK study findings show.

20 Sep 2013

Visual clue to schizophrenia pathology

Researchers say that retinal imaging could be a useful tool for studying some of the pathologic processes associated with schizophrenia.

19 Sep 2013

‘Risk circuits’ for schizophrenia refined

A study sheds further light on the brain circuits that may underlie risk for schizophrenia.

16 Sep 2013

Psychiatrist documents how schizophrenia impacts brain tissue

It's hard to fully understand a mental disease like schizophrenia without peering into the human brain. Now, a study by University of Iowa psychiatry professor Nancy Andreasen uses brain scans to document how schizophrenia impacts brain tissue as well as the effects of anti-psychotic drugs on those who have relapses.

12 Sep 2013