Toxin News and Research

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Researchers reveal how toxins turn healthy proteins into poison to disrupt immune response

Researchers who have revealed a highly efficient way that bacteria use toxins to interrupt the immune response say that until now, the trickery of these toxins has been underappreciated in science.

11 Aug 2015

IU scientists find evidence that invisible war between microorganisms may affect human health

Health experts have warned for years that the overuse of antibiotics is creating "superbugs" able to resist drugs treating infection.

31 Jul 2015

Discovery could put individuals with relapsing UTIs on fast track for new therapeutic regimen

It's one thing to grow bacteria in a test tube, perform a screen in the lab, and find a mutation in the pathogen's genes. It's a whole other thing, and much rarer, to find the exact same mutation in nature--in this case, in E. coli in urine samples from some 500 patients suffering from relapsing urinary tract infections.

30 Jul 2015

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Pathogenic bacteria develop killer machines that work very specifically and highly efficiently. Scientists from the University of Freiburg have solved the molecular mechanism of a fish toxin that could be used in the future as a medication to treat cancer. The scientists have now published their research in the journal Nature Communications.

25 Jul 2015

Tips to prevent, treat black widow and brown recluse spider bites

Most spiders are non-venomous and most spider bites are harmless. They may cause some local redness and pain, but can usually be managed at home by washing, applying ice and keeping the area clean.

22 Jul 2015

Scientists discover new variant of streptococcal bacteria that contributes to severe infections

Scientists have discovered a new variant of streptococcal bacteria that has contributed to a rise in disease cases in the UK over the last 17 years.

15 Jul 2015

UTHealth scientist receives $1.9 million from NIH to develop non-antibiotic treatment for C. diff infections

Charles Darkoh, Ph.D., a researcher at The University of Texas Health Science Center at Houston School of Public Health, was recently awarded a five-year, $1.9 million R01 grant by the National Institutes of Health to develop a non-antibiotic treatment for Clostridium difficile (C. diff) infections.

10 Jul 2015

Aridis expands, accelerates current AR-301 Phase 2a study for treatment of acute pneumonia in the U.S.

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel anti-infectives and immunotherapies for infectious diseases, announced today that the U.S. Food and Drug Administration has accepted its Investigational New Drug (IND) application for AR-301, also referred to as Salvecin, the company's fully human anti-Staphylococcal α-toxin IgG1 monoclonal antibody being developed for the treatment of hospital-acquired and ventilator-associated pneumonia (HAP and VAP) caused by Staphylococcus aureus, including multi-drug resistant 'MRSA' strains.

8 Jul 2015

Two new studies show that fecal transplantation may help fight against ulcerative colitis

Two new studies led by researchers from the Farncombe Family Digestive Health Research Institute at McMaster University show that transplantation of fecal matter may be a useful tool in the fight against ulcerative colitis (UC).

3 Jul 2015

Behavioral flexibility is controlled by specific neurons in the brain

Behavioral flexibility -- the ability to change strategy when the rules change -- is controlled by specific neurons in the brain, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have confirmed.

24 Jun 2015

New research could help reverse side effects of acetaminophen overdose

New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other over-the-counter and prescription medicines.

23 Jun 2015

Link between poverty and kidney disease changes over time, shows study

Poverty is known to be a strong risk factor for end-stage kidney disease. Now, a first of-its-kind study has found that the association between poverty and kidney disease changes over time.

17 Jun 2015

Link between poverty and kidney disease changes over time, study finds

Poverty is known to be a strong risk factor for end-stage kidney disease. Now, a first of-its-kind study has found that the association between poverty and kidney disease changes over time.

16 Jun 2015

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers (H. pylori bacteria).

2 Jun 2015

3-D imaging technique may be useful for measuring efficacy of injectable wrinkle reducers

A three-dimensional imaging technique often used in the automotive and aerospace industries for accurate measurement may be useful to measure the efficacy of injectable wrinkle reducers such as Botox and Dysport, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

28 May 2015

Toxin News and Research

Researchers reveal how toxins turn healthy proteins into poison to disrupt immune response

IU scientists find evidence that invisible war between microorganisms may affect human health

Discovery could put individuals with relapsing UTIs on fast track for new therapeutic regimen

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Tips to prevent, treat black widow and brown recluse spider bites

Scientists discover new variant of streptococcal bacteria that contributes to severe infections

UTHealth scientist receives $1.9 million from NIH to develop non-antibiotic treatment for C. diff infections

Aridis expands, accelerates current AR-301 Phase 2a study for treatment of acute pneumonia in the U.S.

Two new studies show that fecal transplantation may help fight against ulcerative colitis

Behavioral flexibility is controlled by specific neurons in the brain

New research could help reverse side effects of acetaminophen overdose

Link between poverty and kidney disease changes over time, shows study

Link between poverty and kidney disease changes over time, study finds

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Chronic exposure to bacteria may lead to development of Type 2 diabetes

3-D imaging technique may be useful for measuring efficacy of injectable wrinkle reducers

Scorpion venom could kill cancer cells

Aflatoxin exposure associated with increased risk of gallbladder cancer

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Toxin pneumolysin causes progressive and fatal heart complications

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