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Poor handling of oranges in squeezing machines stimulates bacterial contamination

Scientists from the University of Valencia in Spain have analysed fresh orange juice squeezed by machines in catering establishments. They have confirmed that 43% of samples exceeded the acceptable enterobacteriaceae levels laid down by legislation. The researchers recommend that oranges are handled correctly, that juicers are washed properly and that the orange juice is served immediately rather than being stored in metal jugs.

15 Dec 2011

M. pneumoniae CARDS toxin plays a critical role in asthma

Five years ago, microbiologists at The University of Texas Health Science Center San Antonio discovered the toxin produced by a common respiratory bacterial pathogen, Mycoplasma pneumoniae. Joel Baseman, Ph.D., who led the discovery, said at the time that the toxin's presence in humans could be causing as many as 40 percent of all asthma cases.

15 Dec 2011

Researchers uncover important source of inflammation for CKD

UC Irvine researchers have uncovered an important source of inflammation seen in people with chronic kidney disease, which is increasingly common due to the epidemic of obesity-related diabetes and hypertension.

14 Dec 2011

Researchers create vaccine that reduces tumors in mice

Researchers at Mayo Clinic in Arizona and the University of Georgia (UGA) have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases - including those that are resistant to common treatments.

14 Dec 2011

Study to establish zebrafish as functional animal model for V. cholerae

A small fish may prove useful to understanding a worldwide health problem, if a Wayne State University researcher is correct.

13 Dec 2011

Treatment with leukemia patients' own cells may prevent infections after chemotherapy

A new treatment using leukemia patients' own infection-fighting cells appears to protect them from infections and cancer recurrence following treatment with fludarabine-based chemotherapy, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

12 Dec 2011

High gut flora protects children against allergies

High diversity and a variety of bacteria in the gut protect children against allergies as opposed to some individual bacterial genera. These are the findings of a comprehensive study of intestinal microflora (gut flora) in allergic and healthy children, which was conducted at Linköping University in Sweden.

9 Dec 2011

Study identifies tertiary treatment as an important source of antibiotic resistant genes

Water discharged into lakes and rivers from municipal sewage treatment plants may contain significant concentrations of the genes that make bacteria antibiotic-resistant. That's the conclusion of a new study on a sewage treatment plant on Lake Superior in the Duluth, Minn., harbor that appears in ACS' journal Environmental Science & Technology.

8 Dec 2011

Massive and consistent changes in inflammatory gene expression seen in trauma, burns

Serious traumatic injuries, including major burns, set off a "genomic storm" in human immune cells, altering around 80 percent of the cells' normal gene expression patterns. In a report to appear in the December Journal of Experimental Medicine, members of a nationwide research collaborative describe the initial results of their investigation into the immune system response to serious injury, findings which have overturned some longstanding assumptions.

8 Dec 2011

Researchers discover new tick-borne infection

Researchers at the University of Gothenburg's Sahlgrenska Academy have discovered a brand new tick-borne infection. Since the discovery, eight cases have been described around the world, three of them in the Gothenburg area, Sweden.

7 Dec 2011

Study identifies sulfomucins as potential targets for therapies to treat chronic intestinal inflammatory disorders

In a paper published in the December 2011 issue of Experimental Biology and Medicine, a team of scientists at the University of Illinois, Urbana-Champaign led by Rex Gaskins, PhD have demonstrated that both microbial and host inflammatory factors modulate sulfomucin production in a human cell line, LS174T, that models intestinal goblet cells.

3 Dec 2011

New insight into why aminoglycoside antibiotics cause deafness

Peter Steyger's research on hearing is very personal. That's because Steyger - a research scientist with the Oregon Hearing Research Center at Oregon Health & Science University - is deaf. Now Steyger has published groundbreaking research that is as personal as it gets. The study gives scientists new insight into why a specific class of antibiotics causes deafness - the same class of antibiotics that caused Steyger's deafness as a child in England 48 years ago. The study was published this month in Scientific Reports, part of the Nature Publishing Group.

2 Dec 2011

Radioimmunotherapy shows promise against fungal diseases

Invasive fungal infections (IFI) are a major threat to individuals with cancer, transplants, HIV, and other conditions that weaken their immune system. New research has shown that radioimmunotherapy (RIT) could be a promising avenue for development of new types of treatment of fungal diseases, according to a paper published by scientists of the Joint Research Centre (JRC) in collaboration with other researchers.

2 Dec 2011

Harvard SEAS, BASF to co-host symposium on pharmaceutical nanoformulations

From targeted cancer chemotherapy to the guarantee of successful organ transplants, the 21st century may prove to be the age of big ideas in medicine. The drugs themselves, though, will be miniscule. Experts in chemistry, applied physics, materials science, and pharmaceutical science are gathering this week for the BASF Advanced Research Initiative at Harvard University's symposium on pharmaceutical nanoformulations.

1 Dec 2011

Scientists identify 700 anti-bacterial substances from nine species of odorous frogs

Some of the nastiest smelling creatures on Earth have skin that produces the greatest known variety of anti-bacterial substances that hold promise for becoming new weapons in the battle against antibiotic-resistant infections, scientists are reporting.

1 Dec 2011

Researchers reveal stress-induced machinery of protein synthesis involved in bacterial cell death

Researchers at the Hebrew University of Jerusalem and the University of Vienna have revealed for the first time a stress-induced machinery of protein synthesis that is involved in bringing about cell death in bacteria.

1 Dec 2011

Nanomedicine breakthrough by IBN and IBM named a ‘world changer’

A nanoparticle that can destroy drug-resistant bacteria developed by the Institute of Bioengineering and Nanotechnology (IBN), and the IBM Almaden Research Center, has recently been named one of 10 world changing ideas by Scientific American in its Technology Special Report ('World Changing Ideas – 10 New Technologies That Will Make a Difference', December 2011).

29 Nov 2011

New glycoconjugate vaccine prototype more effective than traditional vaccines

Brigham and Women's Hospital (BWH) researchers have created a vaccine that is more potent than traditional vaccines available today. The glycoconjugate vaccine prototype is 100 times more effective than traditional glycoconjugate vaccines. Their work is published in the December 2011 issue of Nature Medicine.

29 Nov 2011

New compound circumvents drug-efflux pumps associated with Gram-positive bacteria

It's no wonder that medicine's effort to combat bacterial infections is often described as an arms race. When new drugs are developed to combat infections, the bacterial target invariably comes up with a deterrent.

29 Nov 2011

Ribosomes spontaneously change their form during protein production

Ribosomes, the construction sites for proteins, are far more complex than previously assumed. During the production of proteins they constantly and spontaneously change their form. This performance of eukaryotic ribosomes has now been demonstrated for the first time by scientists at Charité - Universitätsmedizin Berlin, the Max-Planck-Institut für Molekulare Genetik in Berlin, and Cornell University in New York, with the aid of special electron microscopic and biophysical methods.

24 Nov 2011

Bacterial News and Research

Poor handling of oranges in squeezing machines stimulates bacterial contamination

M. pneumoniae CARDS toxin plays a critical role in asthma

Researchers uncover important source of inflammation for CKD

Researchers create vaccine that reduces tumors in mice

Study to establish zebrafish as functional animal model for V. cholerae

Treatment with leukemia patients' own cells may prevent infections after chemotherapy

High gut flora protects children against allergies

Study identifies tertiary treatment as an important source of antibiotic resistant genes

Massive and consistent changes in inflammatory gene expression seen in trauma, burns

Researchers discover new tick-borne infection

Study identifies sulfomucins as potential targets for therapies to treat chronic intestinal inflammatory disorders

New insight into why aminoglycoside antibiotics cause deafness

Radioimmunotherapy shows promise against fungal diseases

Harvard SEAS, BASF to co-host symposium on pharmaceutical nanoformulations

Scientists identify 700 anti-bacterial substances from nine species of odorous frogs

Researchers reveal stress-induced machinery of protein synthesis involved in bacterial cell death

Nanomedicine breakthrough by IBN and IBM named a ‘world changer’

New glycoconjugate vaccine prototype more effective than traditional vaccines

New compound circumvents drug-efflux pumps associated with Gram-positive bacteria

Ribosomes spontaneously change their form during protein production

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