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Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers assessed the impact of bebtelovimab (BEB) monoclonal antibody in the treatment of high-risk SARS-CoV-2 Omicron variant-infected patients.

13 Dec 2022

Study identifies factors linked to well-being as people age

What are the keys to "successful" or optimal aging? A new study followed more than 7000 middle-aged and older Canadians for approximately three years to identify the factors linked to well-being as we age.

13 Dec 2022

The effectiveness of nirmatrelvir-ritonavir and molnupiravir for the treatment of COVID-19 among US veterans

Researchers evaluated the effectiveness of SARS-CoV-2 antivirals, nirmatrelvir-ritonavir, and molnupiravir among Veterans in the United States of America.

13 Dec 2022

Are you an optimist? Could you learn to be? Your health may depend on it.

When you think about the future, do you expect good or bad things to happen? If you weigh in on the "good" side, you're an optimist. And that has positive implications for your health in later life.

13 Dec 2022

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

Researchers from The University of Texas MD Anderson Cancer Center are presenting compelling findings from three clinical trials at the 2022 American Society of Hematology Annual Meeting.

13 Dec 2022

RNA-targeting CRISPR technology alleviates disease-related phenotypes in Huntington’s models

Huntington's disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function.

12 Dec 2022

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

An international research team led by Dr Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into the mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

12 Dec 2022

Study discovers link between a lesser-known hormone and lipid levels in midlife women

Step aside estrogen. Scientists at the University of Pittsburgh have discovered a predictor of blood lipid - or cholesterol - status for midlife women that may be key to understanding how hormone replacement therapy contributes to heart health.

12 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

New research from cancer research and treatment organization City of Hope in the December 2022 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that only 30% of patients with advanced neuroendocrine tumors (NETs) say their top goal for treatment is living longer.

12 Dec 2022

Light therapy could be a promising non-drug treatment option for multiple sclerosis-related fatigue

Multiple Sclerosis (MS) is almost always accompanied by fatigue, a massive tiredness that is described by the vast majority of patients as the most distressing symptom.

12 Dec 2022

Novel drug shows early potential in combating multiple myeloma

A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer Center at the 2022 American Society of Hematology Annual Meeting (Abstract 565).

12 Dec 2022

Many genetic disorders respond well to specialized gene therapy

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be chromosomal defects that are harmful at birth, in infancy or environment at a later stage.

12 Dec 2022

Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis

Patients with moderate to severe atopic dermatitis who participated in a clinical trial of rocatinlimab - a novel, patient-tailored monoclonal antibody therapy - showed promising results both while taking the drug and up to 20 weeks after the therapy was stopped, Mount Sinai researchers reported in The Lancet.

12 Dec 2022

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

A three-drug combination that sent chronic lymphocytic leukemia (CLL) into deep remissions in a broad group of patients in a clinical trial is highly effective in patients with high-risk forms of the disease, a new, phase 2 clinical trial led by Dana-Farber Cancer Institute investigators indicates.

12 Dec 2022

Extra year of chemotherapy lowers the risk of cancer recurrence in children with Ikaros leukemia

Many children with ALL have a good outcome of their disease. After two years of chemotherapy treatment, nine out of ten children are cured. But some children have a more aggressive form of the disease.

12 Dec 2022

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Researchers from the University of Pennsylvania's Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose cancers relapsed after previous CAR T therapy at the 2022 American Society of Hematology Annual Meeting.

12 Dec 2022

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

12 Dec 2022

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Oregon Health & Science University researchers and partners are developing what could become the first-ever treatment against the debilitating joint pain that can last months or years after becoming infected with the emerging Chikungunya virus.

9 Dec 2022

Therapy News and Research

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Study identifies factors linked to well-being as people age

The effectiveness of nirmatrelvir-ritonavir and molnupiravir for the treatment of COVID-19 among US veterans

Are you an optimist? Could you learn to be? Your health may depend on it.

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

RNA-targeting CRISPR technology alleviates disease-related phenotypes in Huntington’s models

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

Study discovers link between a lesser-known hormone and lipid levels in midlife women

How human cell atlases provide the missing links between genes, diseases and therapies

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

Light therapy could be a promising non-drug treatment option for multiple sclerosis-related fatigue

Novel drug shows early potential in combating multiple myeloma

Many genetic disorders respond well to specialized gene therapy

Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

Extra year of chemotherapy lowers the risk of cancer recurrence in children with Ikaros leukemia

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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