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Anti-cancer drug smuggled using a nanocarrier past protective blood-brain barrier into brain tumours

Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier - a tiny capsule specially designed to pass through cell membranes and deliver its anti-cancer drug to the cancer cell.

18 Nov 2010

Researchers report results from Phase III DEFINE study for coronary heart disease

Researchers today presented results from the Phase III DEFINE (Determining the EFficacy and Tolerability of CETP INhibition with AnacEtrapib) study with Merck's investigational CETP inhibitor, anacetrapib. In the trial of 1,623 patients with coronary heart disease (CHD) or CHD risk equivalents, anacetrapib showed no significant differences from placebo in the primary safety measures studied.

18 Nov 2010

State-of-the-art imaging system helps locate and count myriad connections between brain nerve cells

Researchers at the Stanford University School of Medicine, applying a state-of-the-art imaging system to brain-tissue samples from mice, have been able to quickly and accurately locate and count the myriad connections between nerve cells in unprecedented detail, as well as to capture and catalog those connections' surprising variety.

18 Nov 2010

CARMAT completes assembly of first artificial heart clinical version

CARMAT, the designer and developer of the world's most advanced artificial heart, today announced that it has completed the assembly of the first clinical version of its artificial heart (to be implanted in humans during clinical trials scheduled for 2011).

18 Nov 2010

March of Dimes reports decline in Colorado’s premature birth rate

Premature birth in Colorado has declined along with three key contributing factors, it was reported today by the March of Dimes in its annual assessment, the Premature Birth Report Card. However, despite these improvements (and for the third straight year), the state's overall grade is a "D."

18 Nov 2010

Cardiac stem cells from sick patients could generate new heart muscle: Research

Cardiac stem cells even in elderly and sick patients could generate new heart muscle and vessel tissue and be used to treat heart failure, according to research presented at the American Heart Association's Scientific Sessions 2010.

18 Nov 2010

New findings reveal complexities in close chemical combat waged among bacteria

Like all organisms, bacteria must compete for resources to survive, even if it means a fight to the death. New research led by scientists from the University of North Carolina at Chapel Hill School of Medicine and the University of California, Santa Barbara, describes new complexities in the close chemical combat waged among bacteria.

18 Nov 2010

New technique to identify cancer biomarkers

The University of Liège has presented TARGETOME, the most recent of its spin-offs, which is also the first to spring from its applied geno-proteomics centre, GIGA.

18 Nov 2010

Cigarette smoke, automobile exhaust and french fries increase risk of developing Alzheimer's disease

There is growing evidence that exposure to a group of chemicals known as type-2 alkenes -- which are found in the smoke inhaled from cigarettes, the exhaust of automobiles and even in French fries - can increase the chances of developing Alzheimer's disease and other neurological conditions such as Parkinson's disease.

18 Nov 2010

Scientists solve structure of key protein from Lassa virus

Scientists at Emory University and the University of St. Andrews have solved the structure of a key protein from Lassa virus, which is endemic to West Africa and can cause a deadly hemorrhagic fever.

18 Nov 2010

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

Exelixis, Inc. today reported interim data from the cohort of patients with metastatic castration-resistant prostate cancer (CRPC) treated with XL184 in an ongoing phase 2 adaptive randomized discontinuation trial (RDT).

18 Nov 2010

First Global Symposium on Health Systems Research kicks off in Switzerland

The First Global Symposium on Health Systems Research bringing together researchers, policymakers and donors kicked off in Montreux, Switzerland, on Tuesday, with some conference attendees calling for African leaders to do more to promote health progress in their countries, PANA/Afrique en ligne reports.

18 Nov 2010

Researchers discover NG2+ cells may impact ALS disease progression

By tracking the fate of a group of immature cells that persist in the adult brain and spinal cord, Johns Hopkins researchers discovered in mice that these cells undergo dramatic changes in ALS, also known as Lou Gehrig's disease.

18 Nov 2010

Researchers unveil novel oncogene associated with uveal melanoma

An international, multi-center study has revealed the discovery of a novel oncogene that is associated with uveal melanoma, the most common form of eye cancer.

18 Nov 2010

5-lipoxygenase protein modulates amyloid beta formation linked to Alzheimer's disease

A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine.

18 Nov 2010

Statins activate bacterial-killing properties of white blood cells

Widely prescribed for their cholesterol-lowering properties, recent clinical research indicates that statins can produce a second, significant health benefit: lowering the risk of severe bacterial infections such as pneumonia and sepsis.

18 Nov 2010

Vitamin C can prevent and reverse sepsis

Physicians caring for patients with sepsis may soon have a new safe and cost-effective treatment for this life-threatening illness. Research led by Dr. Karel Tyml and his colleagues at The University of Western Ontario and Lawson Health Research Institute have found that vitamin C can not only prevent the onset of sepsis, but can reverse the disease.

18 Nov 2010

EDP Biotech introduces new blood test for detecting early-stage colon cancer at Medica trade fair

The future of colon cancer screening may be surprisingly simple. ColoMarker, an innovative blood test to detect the early stages of colon cancer is generating plenty of attention from a wide audience, including from some of the world's leading researchers in cancer biomarkers and gastrointestinal medicine.

18 Nov 2010

Study shows end-of-life care varies widely

A new study released by the Dartmouth Atlas of Health Care finds that "America's hospitals treat patients with life-ending cancers very differently in their final months, with some deploying chemotherapy and other life-prolonging efforts until the end and others directing most of their patients into hospice," reports Kaiser Health News. The aggressive care may not be best for patients, and hospice may be a "more humane way to die," the report argues. A point the report doesn't address: that aggressive treatment "also adds to the drain on Medicare's pocketbook."

18 Nov 2010

Researchers are revolutionizing treatment of cardiovascular disease through regenerative stem cell therapy

Northwestern Medicine physician researchers are revolutionizing treatment of cardiovascular disease by utilizing patients' own stem cells to regenerate heart and vascular tissue.

18 Nov 2010

Medicine News and Research

Anti-cancer drug smuggled using a nanocarrier past protective blood-brain barrier into brain tumours

Researchers report results from Phase III DEFINE study for coronary heart disease

State-of-the-art imaging system helps locate and count myriad connections between brain nerve cells

CARMAT completes assembly of first artificial heart clinical version

March of Dimes reports decline in Colorado’s premature birth rate

Cardiac stem cells from sick patients could generate new heart muscle: Research

New findings reveal complexities in close chemical combat waged among bacteria

New technique to identify cancer biomarkers

Cigarette smoke, automobile exhaust and french fries increase risk of developing Alzheimer's disease

Scientists solve structure of key protein from Lassa virus

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

First Global Symposium on Health Systems Research kicks off in Switzerland

Researchers discover NG2+ cells may impact ALS disease progression

Researchers unveil novel oncogene associated with uveal melanoma

5-lipoxygenase protein modulates amyloid beta formation linked to Alzheimer's disease

Statins activate bacterial-killing properties of white blood cells

Vitamin C can prevent and reverse sepsis

EDP Biotech introduces new blood test for detecting early-stage colon cancer at Medica trade fair

Study shows end-of-life care varies widely

Researchers are revolutionizing treatment of cardiovascular disease through regenerative stem cell therapy

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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