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Gene Therapy Contract Development and Manufacturing: Challenges and Future Perspectives

In this interview conducted at the Cell and Gene Therapy Summit Tour London, we speak to Ramin Baghirzade, Global Head of Commercial at Charles River for Gene Therapy, about the Gene Therapy CDMO solutions that Charles River Laboratories offers and more.

From Charles Rivers Laboratories Cell and Gene Therapy 18 Jul 2023

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

Study evaluated genes with copy number alterations to identify biomarkers for ovarian cancer prognosis.

18 Jul 2023

Global burden of diabetes: new study reveals alarming prevalence and projections for 2050

Comprehensive estimates of diabetes prevalence and burden worldwide.

18 Jul 2023

Genes that influence pain perception linked to alcohol use disorders

An estimated 16 million people in the United States have alcohol use disorders (AUDs), according to the National Institutes on Alcohol Abuse and Alcoholism (NIAAA).

17 Jul 2023

Study sheds light on how viruses override host cell's DNA replication machinery

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells.

17 Jul 2023

AI model accurately predicts which drugs may cause birth defects

Data scientists at the Icahn School of Medicine at Mount Sinai in New York and colleagues have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities.

17 Jul 2023

Mitochondrial repair protein discovery may lead to new anti-aging treatments

Researchers at The University of Queensland have found an anti-aging function in a protein deep within human cells.

17 Jul 2023

Merck awards 2023 Future Insight Prize for research into air sensor to detect pandemic pathogens

Merck KGaA, Darmstadt, Germany, awarded its 2023 Future Insight Prize to Khalid Salaita, professor of chemistry at Emory University. The award comes with $540,000 to fund the next phase of research into an air sensor that can continuously monitor indoor spaces for pathogens that can cause pandemics.

17 Jul 2023

Babies have a 'secret weapon' that helps to fight new pathogens

A pair of new studies led by researchers at Columbia University explains why babies get so many common respiratory infections and identifies a specialized cluster of immune cells found only in babies that help them better cope with new pathogens.

17 Jul 2023

Zebrafish study reveals how blood stem cells affect health

All humans have a diverse set of blood stem cell types which dictate the composition and function of our blood and immune cells and ultimately help govern overall health.

17 Jul 2023

New insights into dendritic cell biology could lead to improved cancer therapies

The cells of the immune system circulate mainly in the blood and migrate into the body's tissues after an inflammation. Some types of immune cells, however, are permanently located in the tissues, where they come together to form three-dimensional networks.

17 Jul 2023

Study highlights the potential of cell replacement therapy for Huntington's disease

New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.

17 Jul 2023

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

17 Jul 2023

Donanemab shows promise in slowing Alzheimer's disease

With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease.

17 Jul 2023

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Researchers examined the association between antidrug antibodies and the response to treatments for rheumatoid arthritis.

17 Jul 2023

The role of airway epithelium: insights into asthma and COPD pathogenesis

Study discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma.

17 Jul 2023

Machine learning's potential for rapid LRTI diagnosis

A team of researchers evaluated the use of prediction models in LRTI diagnosis.

17 Jul 2023

Age and immunity: study highlights challenges and opportunities for vaccine protection

Scientists have evaluated molecular mechanisms responsible for heterogeneous responses to influenza vaccination among older adults.

17 Jul 2023

MGI empowers life cienss industry with revolutionary what if campaign at XXIIIrd International Congress of Genetics

MGI Tech Co. Ltd. (MGI), a company committed to building core tools and technology to lead life science, today announced the launch of a global brand campaign titled “What If?” at the XXIII International Congress of Genetics (ICG), a five-yearly conference to bring together the international genetics community from around the world.

From MGI 17 Jul 2023

The prognostic value of PCSK9 levels for predicting major adverse cardiovascular events and mortality in diabetics

Researchers investigate the prognostic value of PCSK9 levels in diabetes patients to predict all-cause mortality and major adverse cardiovascular events.

17 Jul 2023

B Cell News and Research

Gene Therapy Contract Development and Manufacturing: Challenges and Future Perspectives

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

Global burden of diabetes: new study reveals alarming prevalence and projections for 2050

Genes that influence pain perception linked to alcohol use disorders

Study sheds light on how viruses override host cell's DNA replication machinery

AI model accurately predicts which drugs may cause birth defects

Mitochondrial repair protein discovery may lead to new anti-aging treatments

Merck awards 2023 Future Insight Prize for research into air sensor to detect pandemic pathogens

Babies have a 'secret weapon' that helps to fight new pathogens

Zebrafish study reveals how blood stem cells affect health

New insights into dendritic cell biology could lead to improved cancer therapies

Study highlights the potential of cell replacement therapy for Huntington's disease

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Donanemab shows promise in slowing Alzheimer's disease

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

The role of airway epithelium: insights into asthma and COPD pathogenesis

Machine learning's potential for rapid LRTI diagnosis

Age and immunity: study highlights challenges and opportunities for vaccine protection

MGI empowers life cienss industry with revolutionary what if campaign at XXIIIrd International Congress of Genetics

The prognostic value of PCSK9 levels for predicting major adverse cardiovascular events and mortality in diabetics

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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