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Parenchymal preservation surgery linked to lower mortality, complication rates in cancer patients

A surgical approach in which a surgeon removes less than a lobe of the liver in a patient undergoing an operation for liver cancer is associated with lower mortality and complication rates, according to new study results published online as an "article in press" in the Journal of the American College of Surgeons (JACS).

13 Mar 2015

Study describes the dual role of microRNA during hepatitis C infection

In the battle between a cell and a virus, either side may resort to subterfuge. Molecular messages, which control the cellular machinery both sides need, are vulnerable to interception or forgery.

13 Mar 2015

High levels of triglycerides, cholesterol can keep vitamin E tied up in blood stream

In the continuing debate over how much vitamin E is enough, a new study has found that high levels of blood lipids such as cholesterol and triglycerides can keep this essential micronutrient tied up in the blood stream, and prevent vitamin E from reaching the tissues that need it.

13 Mar 2015

Study: New gene therapy safe, effective for patients with hemophilia B

A multi-year, ongoing study suggests that a new kind of gene therapy for hemophilia B could be safe and effective for human patients. Published in the journal Science Translational Medicine, the research showed that a reprogrammed retrovirus could successfully transfer new factor IX (clotting) genes into animals with hemophilia B to dramatically decrease spontaneous bleeding.

12 Mar 2015

WHO releases first-ever guidance for chronic hepatitis B treatment

WHO today issued its first-ever guidance for the treatment of chronic hepatitis B, a viral infection which is spread through blood and body fluids, attacking the liver and resulting in an estimated 650 000 deaths each year - most of them in low- and middle-income countries.

12 Mar 2015

More research needed to explore toxicity of cellulose nanocrystals, says Virginia Tech scientist

Are cellulose nanocrystals harmful to human health? The answer might depend on the route of exposure, according to a review of the literature by a Virginia Tech scientist, but there have been few studies and many questions remain.

12 Mar 2015

Organ-on-a-chip could replace use of animals to test drugs for safety and efficacy

When University of California, Berkeley, bioengineers say they are holding their hearts in the palms of their hands, they are not talking about emotional vulnerability.

12 Mar 2015

Scientists find strong association between MAIT lymphocytes and metabolic dysfunctions

Scientists at Institut Cochin (CNRS/Inserm/Université Paris Descartes) and ICAN - Institute of Cardiometabolism And NutritionInserm/UPMC/AP-HP) have discovered that a class of inflammatory cells, MAIT lymphocytes1, is deregulated in patients suffering from type 2 diabetes and obesity.

12 Mar 2015

Understanding strengths and weaknesses of hepatitis C viruses

Using a specially selected library of different hepatitis C viruses, a team of researchers led by Johns Hopkins scientists has identified tiny differences in the pathogens' outer shell proteins that underpin their resistance to antibodies.

12 Mar 2015

Wistar awarded grant to create Jayne Koskinas Ted Giovanis Breast Cancer Research Consortium

The Jayne Koskinas Ted Giovanis Foundation awarded The Wistar Institute a $1.1 million grant to create The Jayne Koskinas Ted Giovanis Breast Cancer Research Consortium at The Wistar Institute. The Consortium will support the highly synergistic, multidisciplinary research projects of three Wistar scientists dedicated to advancing breast cancer research.

12 Mar 2015

Nuclear medicine in Australia: an interview with Doug Cubbin, ANM Board Chairman

Molybdennum-99 is a central part of Australia’s modern medical system, and is by far the most commonly used radioisotope produced by ANSTO. It decays to Technetium-99m, which is potentially lifesaving as it is used in the diagnosis of heart, conditions, as well as diagnostic procedures associated with kidneys, lungs, bone and the liver.

10 Mar 2015

Clinical study launched to evaluate effectiveness of new HCV therapy in Washington, D.C.

Officials from the National Institutes of Health and the city of Washington, D.C., launched a clinical trial to examine whether primary care physicians and other health care providers, such as nurse practitioners and physician assistants, can use a new antiviral therapy as effectively as specialist physicians to treat people with hepatitis C virus (HCV) infection.

9 Mar 2015

Exposure to hormone-disrupting chemicals can cause fatty liver disease, promote obesity

Exposure to low doses of hormone-disrupting chemicals early in life can alter gene expression in the liver as well as liver function, increasing the susceptibility to obesity and other metabolic diseases in adulthood, a new study finds.

9 Mar 2015

People who quit smoking have improved metabolic effects, new study finds

People who quit smoking have improved metabolic effects, a new study finds. The results will be presented in a poster Thursday, March 5, at ENDO 2015, the annual meeting of the Endocrine Society in San Diego.

9 Mar 2015

FDA approves Astellas' CRESEMBA for treatment of invasive aspergillosis, invasive mucormycosis

Astellas today announced that the U.S. Food and Drug Administration has approved its New Drug Application (NDA) for the use of CRESEMBA (isavuconazonium sulfate), the prodrug for isavuconazole, for patients 18 years of age and older in the treatment of invasive aspergillosis and invasive mucormycosis (also known as zygomycosis).

8 Mar 2015

Women for Positive Action introduces new educational tool for women living with HIV

To mark International Women's Day (March 8, 2015), Women for Positive Action has launched a practical and informative new educational tool entitled 'Hepatitis and coinfection in women living with HIV'. Led by a global, multidisciplinary group of experts, Women for Positive Action is committed to addressing the specific concerns of women living with HIV.

6 Mar 2015

Genetically modified soybean oil has fewer negative metabolic consequences than regular soybean oil

A new soybean oil genetically modified to be healthier than conventional soybean oil causes obesity, pre-diabetes and fatty liver in a nearly identical manner to that of regular soybean oil when part of a typical American high-fat diet, an animal study shows.

6 Mar 2015

GM soybean oil as unhealthy as regular soybean oil, but may not cause insulin resistance

Soybean oil accounts for more than 90 percent of all the seed oil production in the United States. Genetically modified (GM) soybean oil, made from seeds of GM soybean plants, was recently introduced into the food supply on the premise that it is healthier than conventional soybean oil.

6 Mar 2015

Biomarker for compilation of Risk Score for non-alcoholic steatohepatitis

40 percent of people in the EU suffer from non-alcoholic steatohepatitis (fatty liver disease), a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent society. Currently, it is not possible to forecast the further course of the disease - right up to cirrhosis and cancer of the liver. Furthermore, an increased risk of heart attack and kidney damage exists. In future, this should become possible using a Risk Score with different biomarkers.

6 Mar 2015

Common flame retardants linked to obesity, say UH researchers

Could your electronics be making you fat? According to University of Houston researchers, a common flame retardant used to keep electronics from overheating may be to blame.

5 Mar 2015

Liver News and Research

Parenchymal preservation surgery linked to lower mortality, complication rates in cancer patients

Study describes the dual role of microRNA during hepatitis C infection

High levels of triglycerides, cholesterol can keep vitamin E tied up in blood stream

Study: New gene therapy safe, effective for patients with hemophilia B

WHO releases first-ever guidance for chronic hepatitis B treatment

More research needed to explore toxicity of cellulose nanocrystals, says Virginia Tech scientist

Organ-on-a-chip could replace use of animals to test drugs for safety and efficacy

Scientists find strong association between MAIT lymphocytes and metabolic dysfunctions

Understanding strengths and weaknesses of hepatitis C viruses

Wistar awarded grant to create Jayne Koskinas Ted Giovanis Breast Cancer Research Consortium

Nuclear medicine in Australia: an interview with Doug Cubbin, ANM Board Chairman

Clinical study launched to evaluate effectiveness of new HCV therapy in Washington, D.C.

Exposure to hormone-disrupting chemicals can cause fatty liver disease, promote obesity

People who quit smoking have improved metabolic effects, new study finds

FDA approves Astellas' CRESEMBA for treatment of invasive aspergillosis, invasive mucormycosis

Women for Positive Action introduces new educational tool for women living with HIV

Genetically modified soybean oil has fewer negative metabolic consequences than regular soybean oil

GM soybean oil as unhealthy as regular soybean oil, but may not cause insulin resistance

Biomarker for compilation of Risk Score for non-alcoholic steatohepatitis

Common flame retardants linked to obesity, say UH researchers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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