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Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

The study, which appeared in the Journal of Taibah University Medical Sciences, shows that the SARS-CoV-2 may behave akin to the CNS pathogenic mechanism of JEV and HIV during the early stages of infection.

15 Nov 2020

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

A recent study published in the International Journal of Infectious Diseases has explained the lower prevalence of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa compared to that in the US, Europe, and Asia.

15 Nov 2020

Harnessing proteomics could improve therapeutic approaches to COVID-19

A research group in India has recently described how the field of proteomics could be pivotal in helping to tackle the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Modeling suggests lower COVID-19 cases in Lombardy's second wave

Researchers found a negative association between the number of excess deaths during the first wave of the epidemic and the number of second-wave cases. This could be because of both a sort of herd immunity and changes in behavioral response.

12 Nov 2020

Convalescent plasma in COVID-19 can be effective, especially early in disease

A team of researchers in the United States have conducted an extensive literature review looking at the usage of convalescent plasma from recovered COVID-19 patients to treat those with an impaired immune system. Their study, titled “Therapeutic use of convalescent plasma in COVID-19 patients with immunodeficiency: A systematic review,” has been released on medRxiv*, the preprint server.

12 Nov 2020

$Reduced lead exposure may explain the declining rates of hip fracture$

Reduced lead exposure may explain the declining rates of hip fracture

Hip fractures are one of the leading causes of hospitalization among older adults and are a strong predictor of mortality.

12 Nov 2020

Spain's annual life expectancy at birth dropped due to COVID-19 pandemic

Spain's annual life expectancy at birth dropped by 0.9 years between 2019 and the annual period up until July 2020 due to the COVID-19 pandemic, according to a new study published this week in the open-access journal PLOS ONE by Sergi Trias-Llimos of the Center for Demographic Studies, Spain, and colleagues.

11 Nov 2020

Smell and taste changes in general population may indicate COVID-19 spread

Self-reports of smell and taste changes provide earlier markers of the spread of infection of SARS-CoV-2 than current governmental indicators, according to an international team of researchers.

11 Nov 2020

Host genetic "super-variants" may increase COVID-19 death risk

Researchers at Yale University have identified genetic variants among people of white British ancestry that may increase the risk of dying from coronavirus disease 2019 (COVID-19) – the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Nov 2020

Effectiveness of vitamin C against COVID-19 depends on its natural transporter levels

High doses of vitamin C under study for treating COVID-19 may benefit some populations, but investigators exploring its potential in aging say key factors in effectiveness include levels of the natural transporter needed to get the vitamin inside cells.

11 Nov 2020

Machine learning models predict critical events, mortality rate in COVID-19 patients

Mount Sinai researchers have developed machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows.

11 Nov 2020

Preliminary analysis of xenograft versus organoids

The observance of Lung Cancer Awareness Month in November affords an opportunity to take stock of current approaches to lung cancer research, and to cancer research more widely.

11 Nov 2020

Promising new antivirals target arboviruses and SARS-CoV-2: Nodosome inhibitors

A new study describes two promising small molecules that inhibit a host cell factor, called nucleotide binding oligomerization domain-containing protein 2 (NOD2), that inhibits the replication and spread of many arboviruses. This could lead to the development of broad-spectrum antivirals. The study's findings have been published on the preprint server bioRxiv*.

10 Nov 2020