Therapy News and Research

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Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

Diarrhea is no longer the killer it was in the mid-20th century, when an estimated 4.5 million children under age 5 died of it every year.

7 Dec 2022

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Second-line treatment with trastuzumab deruxtecan (T-DXd) led to significantly longer overall survival compared with trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer, according to updated results from the DESTINY-Breast03 phase III clinical trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

Compared with capecitabine-based regimens, trastuzumab deruxtecan (T-DXd) led to higher response rates and longer survival in the third-line setting for patients with HER2-positive metastatic breast cancer previously treated with trastuzumab emtansine (T-DM1), according to results from the phase III DESTINY-Breast02 trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

7 Dec 2022

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

A newly updated clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy and systemic therapy after surgery to treat patients with endometrial cancer.

7 Dec 2022

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Among premenopausal women with hormone receptor (HR)-positive, early-stage breast cancer enrolled in the SOFT trial, those with a high score on a genomic assay called Breast Cancer Index (BCI) had increased risk of distant recurrence, and those with low BCI benefited more from the addition of ovarian suppression therapy to endocrine therapy after 12 years of follow-up, according to data presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Paxlovid has been free so far. Next year, sticker shock awaits.

Nearly 6 million Americans have taken Paxlovid for free, courtesy of the federal government. The Pfizer pill has helped prevent many people infected with covid-19 from being hospitalized or dying, and it may even reduce the risk of developing long covid.

7 Dec 2022

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

Shenandoah Biotechnology Inc., a FUJIFILM Irvine Scientific company and leading manufacturer of recombinant proteins, today announced it has expanded its CTGrade portfolio of cytokines and growth factors for cell and gene therapies manufactured following cGMP guidelines.

From FUJIFILM Irvine Scientific 7 Dec 2022

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Nearly three years into the pandemic, many of us now carry antibodies against the virus - due to an infection or two, a few doses of mRNA vaccine, or a round of monoclonal-antibody treatment.

6 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

Study provide new insights into why cholestasis causes cognitive issues

Patients with cholestatic liver disease such as primary biliary cholangitis (PBC) can experience significant impairment of bile flow and may develop neurological symptoms including fatigue and cognitive decline.

6 Dec 2022

Study suggests new anti-KRAS drug as a strong candidate for pancreatic cancer clinical trials

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human tumors, successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer, researchers from Penn Medicine's Abramson Cancer Center showed, suggesting the drug is a strong candidate for clinical trials.

6 Dec 2022

Parkinson’s drug improves blood pressure, aortic stiffness in adolescents with Type 1 diabetes

Teens with Type 1 diabetes (T1D) who took bromocriptine, a medication used to treat Parkinson's disease and Type 2 diabetes, had lower blood pressure and less stiff arteries after one month of treatment compared to those who did not take the medicine, according to a small study published today in Hypertension, an American Heart Association journal.

6 Dec 2022

Therapy News and Research

Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Paxlovid has been free so far. Next year, sticker shock awaits.

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Research extends the powerful tool of immunotherapy to autoimmune diseases

Study provide new insights into why cholestasis causes cognitive issues

Study suggests new anti-KRAS drug as a strong candidate for pancreatic cancer clinical trials

Parkinson’s drug improves blood pressure, aortic stiffness in adolescents with Type 1 diabetes

The critical role of flow cytometry in CAR+ T-Cell trials

NUS scientists develop novel low-cost method of testing for cancers

Trial assesses the impact of two immunomodulators in reducing CV risk among rheumatoid arthritis patients

New trial to evaluate a potential treatment for irritability in teenagers with autism

Study explores practical pathways to motherhood in women with oncogene-driven lung cancer

Women and men receive different advice on cardiovascular disease prevention

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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