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New optical nanosensor enables spatiotemporal mapping of the brain with improved accuracy

A new optical nanosensor enabling more accurate measurement and spatiotemporal mapping of the brain also shows the way forward for design of future multimodal sensors and a broader range of applications, say researchers in an article published in the current issue of Neurophotonics.

2 Mar 2017

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins that can be expensive to manufacture.

2 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

Study: Nonoperative management of abdominal gunshot wounds is safe option in selected patients

At one time, trauma surgeons considered an operation mandatory to treat gunshot wounds to the abdomen, but a study published online as an "article in press" on the Journal of the American College of Surgeons website has found that in selected patients, avoiding an operation--a practice known as nonoperative management--is an acceptable and effective treatment.

2 Mar 2017

Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Researchers explore changes in prevalence of depression among current, former and never smokers

The prevalence of smoking has remained fairly stable over the past decade after declining sharply for many years.

1 Mar 2017

Study finds only 16% of heart attack survivors get recommended amount of physical activity

Only 16 percent of heart attack survivors get the recommended amount of physical activity in the weeks after hospitalization, according to a study by researchers at Columbia University Medical Center and NewYork-Presbyterian.

1 Mar 2017

Desk-bound jobs linked to bigger waists and increased risk of heart disease

A new study shows further evidence for the view that spending too much time sitting down is bad for our health and our waistline.

1 Mar 2017

Study: People with intermittent explosive disorder at greater risk for substance abuse

People with intermittent explosive disorder—a condition marked by frequent physical or verbal outbursts—are at five times greater risk for abusing substances such as alcohol, tobacco and marijuana than those who don't display frequent aggressive behavior, according to a new study by researchers from the University of Chicago.

1 Mar 2017

Affordable Care Act improves access to primary care for Medicaid patients, Penn study finds

Since the introduction of the Affordable Care Act, which provided access to health insurance to millions of previously uninsured adults in the United States, the availability of appointments with primary care physicians has improved for patients with Medicaid and remains unchanged for patients with private coverage, according to new research led by the Perelman School of Medicine and the Leonard Davis Institute of Health Economics at the University of Pennsylvania.

28 Feb 2017

Hypoxia may be cause for seizure-related neuronal degeneration in epilepsy, study finds

Neuronal degeneration is the most severe long-term consequence of repetitive seizures in patients with epilepsy, which until now was thought to be primarily caused by excitotoxicity, or over-stimulation of the neurons.

27 Feb 2017

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.

24 Feb 2017

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Researchers from Columbia University Medical Center have found that, for many patients, an initial diagnosis of "acute kidney injury" may have been inaccurate.

24 Feb 2017

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Current treatments for rheumatoid arthritis relieve the inflammation that leads to joint destruction, but the immunologic defect that triggers the inflammation persists to cause relapses, according to research conducted at NYU Langone Medical Center and the University of Pittsburgh.

24 Feb 2017

Medical School News and Research

New optical nanosensor enables spatiotemporal mapping of the brain with improved accuracy

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Study: Nonoperative management of abdominal gunshot wounds is safe option in selected patients

Highly prevalent gene variants in African Americans contribute to kidney disease

Researchers explore changes in prevalence of depression among current, former and never smokers

Study finds only 16% of heart attack survivors get recommended amount of physical activity

Desk-bound jobs linked to bigger waists and increased risk of heart disease

Study: People with intermittent explosive disorder at greater risk for substance abuse

Affordable Care Act improves access to primary care for Medicaid patients, Penn study finds

Hypoxia may be cause for seizure-related neuronal degeneration in epilepsy, study finds

MGH researchers discover regulators of gene expression programs in medulloblastoma

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Researchers reveal biological pathways involved in diabetic kidney disease

Study uncovers how effects of HSP90 protein can alter course of genetic diseases

Cocaine use by fathers may negatively impact cognitive development in male offspring

Study reveals growing problem of diabetic retinopathy among youth

BIDMC review focuses on neural circuitry of wakefulness and sleep

New research pinpoints how immigrant microbes get to the lungs

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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