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Genkyotex announces initiation of GKT137831 Phase II study in patients with diabetic nephropathy

Genkyotex, the leading developer of selective NOX enzyme inhibitors, announced today the initiation of a multinational Phase II clinical study of GKT137831 in patients with diabetic nephropathy.

5 Nov 2013

Research findings could offer new insights into how defective cells can multiply in diseases

A rudimentary form of life that is found in some of the harshest environments on earth is able to sidestep normal replication processes and reproduce by the back door, researchers at The University of Nottingham have found.

5 Nov 2013

Researchers study quality, effectiveness and safety of generic drugs used to treat depression

Researchers at Washington University School of Medicine in St. Louis are studying the quality, effectiveness and safety of generic drugs used to treat depression.

4 Nov 2013

Solution for enzyme-based diagnostic testing in remote locations to be exhibited by Sherwood Scientific at MEDICA 2013

Sherwood Scientific Ltd will exhibit the CHROMA Model 260uv Programmable Colorimeter for the first time at MEDICA 2013 (20 - 23 November 2013, Düsseldorf Fairgrounds, Germany). The instrument allows users to conduct enzyme-based tests in challenging and remote locations without access to a laboratory. Also on display at MEDICA will be Sherwood Scientific’s magnetic susceptibility balance and the model 926S Chloride analyser, both valuable and established tools in clinical applications.

1 Nov 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Making fat cells immortal might seem like a bad idea to most people, but for a team of University of Iowa scientists it was the ideal way to study how the interaction between bacteria and fat cells might contribute to diabetes.

31 Oct 2013

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Experiments by scientists at Johns Hopkins and in Boston have unraveled two biological mechanisms as the major cause of protein citrullination in rheumatoid arthritis. Protein citrullination is suspected of sparking the immune system and driving the cascade of events leading to the disease.

31 Oct 2013

Meclizine drug has the potential to treat certain infectious diseases and cancer

Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Dr. Vishal M. Gohil, Texas A&M AgriLife Research biochemist.

31 Oct 2013

Honey may be detrimental for patients with type 2 diabetes

Honey may be detrimental for patients with type 2 diabetes because of the great quantities of sugars it contains.

31 Oct 2013

New understanding of sperm capacitation may improve IVF success rates

Two new papers from reproductive biologists at the University of Massachusetts Amherst, with international partners, report advances in understanding the basic processes of sperm capacitation that may one day improve success rates of in vitro fertilization (IVF) by providing a shortcut to bypass problems, and may eventually lead to a male contraceptive.

29 Oct 2013

Study shows how wrong levels of protein linked with AD can lead to dangerous blockages in brain cells

Scientists have known for some time that a protein called presenilin plays a role in Alzheimer's disease, and a new study reveals one intriguing way this happens.

29 Oct 2013

Incyte announces results of Phase II clinical trial of oral JAK1 inhibitor in patients with RA

Incyte Corporation (Nasdaq: INCY) announced results from a 12-week, placebo-controlled, dose-escalationin involving 60 patients with active rheumatoid arthritis for its proprietary oral JAK1 inhibitor.

29 Oct 2013

Scientists develop new drug to treat obstructive airway diseases

Scientists have developed a new drug (RPL554) that could treat obstructive airway diseases such as asthma and chronic obstructive pulmonary disease in two ways at once, according to new research published in The Lancet Respiratory Medicine.

25 Oct 2013

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

"Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved," explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University. "Because they also lower cholesterol levels, they are extensively used in the food industry and as dietary supplements."

25 Oct 2013

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Nanyang Technological University (NTU) today launched a new electron microscopy lab led by world renowned scientist Professor Daniela Rhodes. Named the NTU Cryo-Electron Microscopy Laboratory, it is also the world's first university research facility to be equipped with an advanced cryo transmission electron microscope fitted with the latest detector/camera ten times more sensitive than a regular electron microscopy camera.

25 Oct 2013

Just 13 days in space may cause changes in eye structure, gene expression

Just 13 days in space may be enough to cause profound changes in eye structure and gene expression, report researchers from Houston Methodist, NASA Johnson Space Center, and two other institutions in the October 2013 issue of Gravitational and Space Research.

25 Oct 2013

Alexion Pharma's replacement therapy gets FDA Breakthrough Therapy designation for MoCD Type A

Alexion Pharma International Sàrl, a subsidiary of Alexion Pharmaceuticals, Inc., today announced that the U.S. Food and Drug Administration has granted a Breakthrough Therapy designation to cyclic pyranopterin monophosphate (cPMP, or ALXN1101), an enzyme co-factor replacement therapy for the treatment of patients with molybdenum cofactor deficiency type A, a severe and life-threatening, ultra-rare, genetic metabolic disorder that causes catastrophic and irreversible neurologic damage within the first weeks of life.

24 Oct 2013

Study shows plant sterols appear to prevent onset of Alzheimer's disease

It's no secret that many of the phytochemicals in fruit and vegetables have a positive effect on our health. For instance, plant sterols (also known as phytosterols) help to lower cholesterol levels. According to a new study by researchers at Saarland University, they also appear to prevent the onset of Alzheimer's disease.

24 Oct 2013

New Centre for Stratified Medicine opened in Ireland

The University of Ulster has opened a new Centre for Stratified Medicine. The only Centre of its kind in Ireland, £11.5m research facility in Derry~Londonderry puts the University at the forefront of medical research into chronic degenerative diseases.

24 Oct 2013

ASN strongly recommends all adults to undergo routine screening for chronic kidney disease

The American Society of Nephrology strongly recommends that all adults undergo routine screening for chronic kidney disease (CKD), the 8th leading cause of death in the U.S. This contradicts screening guidelines recently released by the American College of Physicians (ACP).

23 Oct 2013

Three cups of coffee per day reduce liver cancer risk by more than 50%

Coffee consumption reduces risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, by about 40 percent, according to an up-to-date meta-analysis published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

23 Oct 2013

Enzyme News and Research

Genkyotex announces initiation of GKT137831 Phase II study in patients with diabetic nephropathy

Research findings could offer new insights into how defective cells can multiply in diseases

Researchers study quality, effectiveness and safety of generic drugs used to treat depression

Solution for enzyme-based diagnostic testing in remote locations to be exhibited by Sherwood Scientific at MEDICA 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Meclizine drug has the potential to treat certain infectious diseases and cancer

Honey may be detrimental for patients with type 2 diabetes

New understanding of sperm capacitation may improve IVF success rates

Study shows how wrong levels of protein linked with AD can lead to dangerous blockages in brain cells

Incyte announces results of Phase II clinical trial of oral JAK1 inhibitor in patients with RA

Scientists develop new drug to treat obstructive airway diseases

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Just 13 days in space may cause changes in eye structure, gene expression

Alexion Pharma's replacement therapy gets FDA Breakthrough Therapy designation for MoCD Type A

Study shows plant sterols appear to prevent onset of Alzheimer's disease

New Centre for Stratified Medicine opened in Ireland

ASN strongly recommends all adults to undergo routine screening for chronic kidney disease

Three cups of coffee per day reduce liver cancer risk by more than 50%

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