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HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

Researchers develop new automated platform for in-depth analyses of MRI scans

One of the main tools doctors use to detect diseases and injuries in cases ranging from multiple sclerosis to broken bones is magnetic resonance imaging.

16 Feb 2017

New guidelines provide expanded treatment options for millions of women living with heart failure

At least one person is diagnosed with heart failure every minute. Of those living with the disease, half are women.

16 Feb 2017

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

More than six decades after Castleman disease was first described, a group of experts from Penn Medicine and other institutions around the world has established the first set of diagnostic criteria for a life-threatening subtype of the condition, idiopathic multicentric CD, which is often misdiagnosed as other illnesses.

16 Feb 2017

IDSA guidelines: Team approach vital to successful treatment of complex neurological infections

A team approach is vital to the successful diagnosis and treatment of complex neurological infections related to placement of devices in the brain, or as a result of neurosurgery or head trauma.

16 Feb 2017

Signals from fat cells may aid in diagnostics for metabolic conditions

Fat cells are not simply big blobs of lipid quietly standingby in the body--instead, they send out hormones and other signaling proteins that affect many types of tissues.

15 Feb 2017

Review: Biomimetic strategies for bone healing need to emulate natural regenerative mechanisms

The range of biomimetic approaches to promote bone growth that are at the core of current bone healing therapies need to more closely emulate natural regenerative mechanisms.

15 Feb 2017

Physician's choice of insomnia medication may be based on habit, new research shows

Clinical decision-making is a complex process, driven by multiple factors, including social and psychological dynamics, peer pressure and even exposure to drug advertising.

15 Feb 2017

Researchers propose new system to evaluate PrEP-based care for HIV prevention

One of the most promising new approaches to slowing the spread of HIV is pre-exposure prophylaxis (PrEP), a once-a-day medication that people who don't have HIV can take to prevent becoming infected.

15 Feb 2017

Only subset of mother's HIV virus infects infants during pregnancy or breastfeeding, research shows

In the transmission of HIV-1 from mother to child only a subset of a mother's viruses infects their infants either in utero or via breastfeeding, and the viruses that are transmitted depend on whether transmission occurs during pregnancy or through breastfeeding, according to UCLA-led research.

15 Feb 2017

Rutgers-Princeton Center aims to improve diagnosis of psychiatric diseases using computational models

A new center is bringing together researchers from Princeton and Rutgers universities to apply computational modeling to the understanding of psychiatric diseases.

15 Feb 2017

Drug given to reduce side effects of pain medication may facilitate gastrointestinal recovery after testicular cancer surgery

Post-operative recovery and length of hospital stay are critical things to consider when having major surgery. A drug commonly given to reduce the side effects of strong post-surgery pain medications has been found to reduce the length of hospital stays for patients who have undergone major gastrointestinal or bladder cancer procedures.

15 Feb 2017

U-M researchers envision new ways to avoid inappropriate ER use for mild eye problems

Pinkeye isn't a medical emergency. Neither is a puffy eyelid. But a new study finds that nearly one in four people who seek emergency care for eye problems have those mild conditions, and recommends ways to help those patients get the right level of care.

15 Feb 2017

Scientists identify genetic signature of risk for type 2 diabetes

Why do some people get Type 2 diabetes, while others who live the same lifestyle never do? For decades, scientists have tried to solve this mystery - and have found more than 80 tiny DNA differences that seem to raise the risk of the disease in some people, or protect others from the damagingly high levels of blood sugar that are its hallmark.

14 Feb 2017

Joslin Diabetes Center participating in two clinical trials to test artificial pancreas systems

Joslin Diabetes Center will take part in two clinical trials this year to test artificial pancreas systems designed to automatically monitor and regulate blood glucose levels in people with type 1 diabetes, which would replace traditional methods of managing the disease such as testing blood glucose levels by finger stick or using continuous glucose monitoring systems with separate, non-integrated delivery of insulin by either injections or a pump.

14 Feb 2017

Penn Medicine's ODC collaborates with FAST to develop gene therapy for Angelman syndrome

Penn Medicine's Orphan Disease Center announces a new partnership with FAST to study gene therapy approaches to treat Angelman syndrome.

14 Feb 2017

Study finds sharp rise in number of older Americans taking multiple brain-affecting drugs

The number of older Americans who take three or more medicines that affect their brains has more than doubled in just a decade, a new study finds.

14 Feb 2017

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

A father's nicotine use may have a significant impact on children's risk of some diseases. In a study published in the online biomedical sciences journal eLife, Oliver J. Rando, MD, PhD, and colleagues at UMass Medical School, demonstrate that mice born of fathers who are habitually exposed to nicotine inherit enhanced chemical tolerance and drug clearance abilities.

14 Feb 2017

Scientists discover population of progenitor cells linked to formation of heart’s ventricular chambers

A population of cells in early development may give rise to the ventricular chambers of the heart, but not the atria, according to a study led by researchers from the Mindich Child Health and Development Institute at the Icahn School of Medicine at Mount Sinai and published today in Nature Communications.

14 Feb 2017

Researchers decode how ingenious tick immune system fights myriad of microbes

Everyone agrees that ticks are exceedingly nasty creatures. For hundreds of millions of years, they have survived on Earth by sucking blood from their victims for days, often leaving behind terrible diseases as a thank-you note.

14 Feb 2017

Medical School News and Research

HMS scientists listen to crosstalk between gut microbes and immune system

Researchers develop new automated platform for in-depth analyses of MRI scans

New guidelines provide expanded treatment options for millions of women living with heart failure

Experts establish first set of diagnostic criteria for life-threatening idiopathic multicentric CD

IDSA guidelines: Team approach vital to successful treatment of complex neurological infections

Signals from fat cells may aid in diagnostics for metabolic conditions

Review: Biomimetic strategies for bone healing need to emulate natural regenerative mechanisms

Physician's choice of insomnia medication may be based on habit, new research shows

Researchers propose new system to evaluate PrEP-based care for HIV prevention

Only subset of mother's HIV virus infects infants during pregnancy or breastfeeding, research shows

Rutgers-Princeton Center aims to improve diagnosis of psychiatric diseases using computational models

Drug given to reduce side effects of pain medication may facilitate gastrointestinal recovery after testicular cancer surgery

U-M researchers envision new ways to avoid inappropriate ER use for mild eye problems

Scientists identify genetic signature of risk for type 2 diabetes

Joslin Diabetes Center participating in two clinical trials to test artificial pancreas systems

Penn Medicine's ODC collaborates with FAST to develop gene therapy for Angelman syndrome

Study finds sharp rise in number of older Americans taking multiple brain-affecting drugs

Children born of fathers exposed to nicotine inherit enhanced chemical tolerance, study shows

Scientists discover population of progenitor cells linked to formation of heart’s ventricular chambers

Researchers decode how ingenious tick immune system fights myriad of microbes

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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