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New project aims to revolutionize application of optogenetics in neuroscience

The revolution that optogenetics technology has brought to biology -- neuroscience in particular -- could be transformed all over again if a new project getting underway at Brown University and Central Michigan University is successful.

17 Jul 2015

Neuronal activity in the brain's prefrontal cortex is nuanced and complex, new study finds

Results of a new study reported this week by David Moorman of the University of Massachusetts Amherst and Gary Aston-Jones of Rutgers University suggest that adjusting behavior based on previous events involves an unexpected mix of neurons working together in the brain's prefrontal cortex.

17 Jul 2015

Kessler Foundation, University of Bordeaux team up to study emotional processing deficits in MS people

Kessler Foundation received $65,500 as part of a two-year $140,000 grant from the ARSEP Foundation of France to the University of Bordeaux, to launch a collaborative study of emotional processing deficits in people with multiple sclerosis (MS). Helen Genova, Ph.D., and Jean Lengenfelder, Ph.D., of Kessler Foundation and Bruno Brochet, M.D., Ph.D., of the University of Bordeaux are the principal investigators.

17 Jul 2015

Novel cancer drug candidate developed in Singapore advances into clinical trials

A made-in-Singapore cancer drug has advanced into clinical trials, charting a milestone in Singapore's biomedical sciences initiative that will go towards improving the lives of cancer patients in Singapore, and worldwide.

17 Jul 2015

Major study to assess effectiveness of mindfulness training in UK schools

The three-part study includes the first large randomised control trial of mindfulness training compared with 'teaching as usual' in 76 schools, which will involve nearly six thousand students aged 11 to 14. Other parts of the study are a programme of experimental research to establish whether and how mindfulness improves the mental resilience of teenagers, and an evaluation of the most effective way to train teachers to deliver mindfulness classes to students.

16 Jul 2015

New findings point toward potential blood test to detect schizophrenia

High blood levels of a growth factor known to enable new blood vessel development and brain cell protection correlate with a smaller size of brain areas key to complex thought, emotion and behavior in patients with schizophrenia, researchers report in the journal Molecular Psychiatry.

16 Jul 2015

Scientists discover protein that plays significant role in development of fragile X syndrome

Scientists at VIB and KU Leuven have discovered that the protein APP plays a significant role in the development of fragile X syndrome (FXS) at young stages. They identified an unexpected biological pathway as a promising target to ameliorate deficits associated with FXS and autism. The results have recently been published in Neuron, one of the most influential journals in the field of neuroscience.

16 Jul 2015

New imaging technique could help with early detection of Alzheimer's disease

Various types of information can be ascertained by the way blood flows through the brain. When a region of the brain has been activated, blood flow increases and oxygenation rises. By observing variations in blood flow with the help of non-invasive imaging, it is possible to determine which regions are at work at a given point in time and how they work together.

16 Jul 2015

Iowa researchers gain important insight into sudden unexpected death in epilepsy

Sudden unexpected death in epilepsy (SUDEP) is becoming increasingly recognized as a very real and devastating problem in which impaired breathing is thought to play a critical role. Researchers believe breathing may be impaired during and after seizures, without the patient's knowledge.

16 Jul 2015

Key parts of the human brain network give power to control, redirect attention

Researchers at Columbia University Medical Center have found that key parts of the human brain network that give us the power to control and redirect our attention--a core cognitive ability--may be unique to humans.

16 Jul 2015

TSRI scientists reveal how mutations in specific autism risk gene alter pattern of early brain development

As early as 1943, when autism was first described by psychiatrist Leo Kanner, reports were made that some, but not all, children with autism spectrum disorder have relatively enlarged heads. But even today, more than half a century later, the exact cause of this early abnormal growth of the head and brain has remained unclear.

16 Jul 2015

Researchers create clinical pathway to identify OSA in high-risk, hospitalized patients

Obstructive Sleep Apnea (OSA) remains under-recognized in hospitalized patients, despite being associated with cardiovascular complications and sudden death. A multi-disciplinary group of researchers and physicians at Thomas Jefferson University and Hospitals have created a clinical pathway, or screening process, to identify the disorder in higher-risk, hospitalized patients and recently published the results in the Journal of Clinical Sleep Medicine.

16 Jul 2015

Potential diagnostic approach may detect individuals at increased risk for Alzheimer's disease

Individuals with amnestic mild cognitive impairment (aMCI) are at twice the risk of others in their age group of progressing to Alzheimer's disease. Although no conclusive test exists to predict who will develop Alzheimer's, new research from the Center for BrainHealth at The University of Texas at Dallas is attempting to identify a potential biomarker that could offer a more complete picture of who is most at risk.

16 Jul 2015

Research could lead to new approaches to treating spinal cord and brain injuries

Many an injury will heal, but the damaged spinal cord is notoriously recalcitrant. There's new hope on the horizon, though. A team of researchers led by the University of South Carolina's Jeff Twiss just reported an innate repair mechanism in central nervous system axons that might be harnessed to regenerate nerves after brain or spinal cord injuries.

16 Jul 2015

University of Bristol-led study could provide new target for treating neurological disorders

Findings, published today [15 Jul] in Nature Communications, reveal the extent a mutation associated with autism and epilepsy plays in impairing a biochemical process in the brain. The study, led by University of Bristol researchers, could provide a new target for treating neurological disorders.

16 Jul 2015

Salk researchers move one step closer to making cures for genetic diseases a reality

Healthy brain, muscle, eye and heart cells would improve the lives of tens of thousands of people around the world with debilitating mitochondrial diseases. Now, researchers at the Salk Institute have gotten one step closer to making such cures a reality: they've turned cells from patients into healthy, mutation-free stem cells that can then become any cell type.

16 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury.

15 Jul 2015

New research may explain why youngsters' recovery times vary widely after traumatic brain injury

Why do some youngsters bounce back quickly from a traumatic brain injury, while others suffer devastating side effects for years? New UCLA/USC research suggests that damage to the fatty sheaths around the brain's nerve fibers--not injury severity-- may explain the difference. Published in the July 15 edition of the Journal of Neuroscience, the finding identifies possible biomarkers that physicians could use to predict higher-risk patients who require closer monitoring.

15 Jul 2015

New study reveals highly promising approach to coating tissue engineered constructs

A new study showing the ability to apply a thin coating of viable respiratory epithelial cells to tissue engineered constructs using a commercially available spray device is especially promising for therapeutic approaches in development to repair or replace challenging structures such as trachea or bronchi.

15 Jul 2015

Neuroscience News and Research

New project aims to revolutionize application of optogenetics in neuroscience

Neuronal activity in the brain's prefrontal cortex is nuanced and complex, new study finds

Kessler Foundation, University of Bordeaux team up to study emotional processing deficits in MS people

Novel cancer drug candidate developed in Singapore advances into clinical trials

Major study to assess effectiveness of mindfulness training in UK schools

New findings point toward potential blood test to detect schizophrenia

Scientists discover protein that plays significant role in development of fragile X syndrome

New imaging technique could help with early detection of Alzheimer's disease

Iowa researchers gain important insight into sudden unexpected death in epilepsy

Key parts of the human brain network give power to control, redirect attention

TSRI scientists reveal how mutations in specific autism risk gene alter pattern of early brain development

Researchers create clinical pathway to identify OSA in high-risk, hospitalized patients

Potential diagnostic approach may detect individuals at increased risk for Alzheimer's disease

Research could lead to new approaches to treating spinal cord and brain injuries

University of Bristol-led study could provide new target for treating neurological disorders

Salk researchers move one step closer to making cures for genetic diseases a reality

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

New research may explain why youngsters' recovery times vary widely after traumatic brain injury

New study reveals highly promising approach to coating tissue engineered constructs

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