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New study finds that intellectual pursuits can buffer the brain's reward system against drug dependence

Challenging the idea that addiction is hardwired in the brain, a new UC Berkeley study of mice suggests that even a short time spent in a stimulating learning environment can rewire the brain's reward system and buffer it against drug dependence.

15 Jul 2015

Studies using MRI techniques can reveal brain connectivity differences in people with ASD

Studies using magnetic resonance imaging (MRI) techniques are beginning to reveal differences in brain connectivity--the ways that different parts of the brain are connected to each other and work together--in people with autism spectrum disorders (ASD), reports a review in the Harvard Review of Psychiatry.

15 Jul 2015

Hyperbaric oxygen treatment effective for fibromyalgia

Fibromyalgia is almost impossible to diagnose. The chronic pain syndrome strikes an estimated 1 in 70 Americans, most of them women. The disorder is often triggered by head trauma, a neurological infection, or severe emotional stress, and is characterized by symptoms such as musculoskeletal pain, fatigue, memory loss and mood swings. Fibromyalgia is often mistaken for other culprits and most patients suffer months, even years, of unrelenting pain before being properly diagnosed. And once diagnosed, patients enjoy little respite because few therapies have been found to be effective in assuaging its symptoms.

15 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Sleep loss makes memories less accessible during stressful situations

It is known that sleep facilitates the formation of long-term memory in humans. In a new study, researchers from Uppsala University, Sweden, now show that sleep does not only help form long-term memory but also ensures access to it during times of cognitive stress.

14 Jul 2015

New study reveals how communication patterns sustain relationships between couples affected by AD

When a spouse is cognitively impaired, marital communication is impaired. As Alzheimer's disease (AD) progresses, language problems increase in frequency - such as searching for the right word, repeating the same word, asking the same question over and over, or substituting one word for another.

14 Jul 2015

Single molecule appears to be central regulator driving cancer metastasis

Cancer is a disease of cell growth, but most tumors only become lethal once they metastasize or spread from their first location to sites throughout the body. For the first time, researchers at Thomas Jefferson University in Philadelphia report a single molecule that appears to be the central regulator driving metastasis in prostate cancer.

14 Jul 2015

UM researchers discover new gene behind neurodegenerative conditions

Researchers at the University of Miami have discovered and characterized a previously unknown disease gene linked to the degeneration of optic and peripheral nerve fibers. The study titled "Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder" is published in the journal Nature Genetics.

14 Jul 2015

Gene function in the human brain could help reveal basis of autism

UNSW Australia scientists have discovered a link between autism and genetic changes in some segments of DNA that are responsible for switching on genes in the brain.

14 Jul 2015

New incoming nerve cell connections could be contributing to age-related hearing loss, say Johns Hopkins scientists

Conventional wisdom has long blamed age-related hearing loss almost entirely on the death of sensory hair cells in the inner ear, but research from neuroscientists at Johns Hopkins has provided new information about the workings of nerve cells that suggests otherwise.

13 Jul 2015

Three European medical centers planning upgrades to Elekta's stereotactic radiosurgery system for the brain

Three foremost medical centers in the United Kingdom and Germany have ordered and are now planning upgrades to Elekta's latest generation stereotactic radiosurgery system for the brain, Leksell Gamma Knife Icon, to provide the most advanced brain radiosurgery treatments for their patients.

From Elekta 13 Jul 2015

Activating bacterial receptors boosts macrophage response, limits damage to spinal cord following injury

Macrophages are cellular sentinels in the body, assigned to identify "attacks" from viruses, bacteria, or fungi and sound the alarm when they are present. However, these cells are a "double edged sword" in spinal cord injury, providing both neural repair-promoting properties and pathological functions that destroy neuronal tissue

13 Jul 2015

Connexient, RWJUH announce public launch of MediNav Navigator Edition 2.0

Connexient and Robert Wood Johnson University Hospital announced this week the public launch of MediNav Navigator Edition 2.0. This makes RWJUH the first hospital in North America to deliver for its patients, visitors and staff the world's first true turn-by-turn indoor navigation smartphone application, with reliable indoor positioning accuracy of one to two meters.

10 Jul 2015

Potential molecular link identified between excess fat in the blood and blood vessel recovery in ischemia

The buildup of fat in the blood makes a bad situation worse - it not only raises a person's risk for heart attack or stroke but also impairs the growth of new blood vessels. How excess fat in the blood - a condition known as hyperlipidemia - blocks vessel growth was unclear, but new work by researchers at Temple University School of Medicine shows that a molecule known as caspase-1 plays a central role and that preventing its activity could be the key to building new blood vessels and restoring blood supply to oxygen-starved tissues.

10 Jul 2015

Retrosplenial cortex serves as 'conjunction junction' for brain's navigation function

Ever wake at night needing a drink of water and then find your way to the kitchen in the dark without stubbing your toe?

10 Jul 2015

Tillotts Pharma to purchase global rights for AstraZeneca’s Entocort excluding the U.S.

Tillotts Pharma AG, part of the Zeria Group, announced today that it has entered into an agreement for the acquisition of the global rights for Entocort (budesonide) from AstraZeneca, excluding the U.S., which will remain with AstraZeneca.

9 Jul 2015

New UCLA study reveals genetic architecture of schizophrenia

A new study by UCLA scientists adds to the understanding of the genetic architecture of schizophrenia. Past research has shown the impact of commonly occurring genetic variants on a person's risk of developing schizophrenia. This new study focused instead on rare coding mutations that affect protein function. It found that patients with schizophrenia have a higher-than-normal share of these mutations.

9 Jul 2015

Janssen-sponsored Phase 2b trial shows guselkumab effective in treating moderate to severe plaque psoriasis

Results published today in The New England Journal of Medicine from a Janssen Research & Development, LLC (Janssen)-sponsored Phase 2b trial showed up to 86 percent of patients with moderate to severe plaque psoriasis receiving guselkumab (CNTO 1959) achieved a Physician's Global Assessment (PGA) score of cleared psoriasis or minimal psoriasis at week 16, the study's primary endpoint.

9 Jul 2015

EvoRx Technologies, AstraZeneca successfully complete research collaboration

AstraZeneca and EvoRx Technologies successfully completed a one-year research collaboration leveraging EvoRx's proprietary Evo-Link technology to discover cell penetrating peptides for a high value intracellular protein–protein interaction target in the respiratory portfolio.

9 Jul 2015

Johns Hopkins, IOCB Prague sign drug discovery research agreement

The Johns Hopkins Drug Discovery (JHDD) program, created with the mission of identifying novel drug targets arising from Johns Hopkins faculty research and translating them into new therapeutics, and the Institute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences (IOCB Prague) have entered into a five-year drug discovery research agreement to develop small-molecule and peptide drugs for a range of therapeutic areas including neurological diseases, cancer and gastrointestinal disorders.

9 Jul 2015

Neuroscience News and Research

New study finds that intellectual pursuits can buffer the brain's reward system against drug dependence

Studies using MRI techniques can reveal brain connectivity differences in people with ASD

Hyperbaric oxygen treatment effective for fibromyalgia

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Sleep loss makes memories less accessible during stressful situations

New study reveals how communication patterns sustain relationships between couples affected by AD

Single molecule appears to be central regulator driving cancer metastasis

UM researchers discover new gene behind neurodegenerative conditions

Gene function in the human brain could help reveal basis of autism

New incoming nerve cell connections could be contributing to age-related hearing loss, say Johns Hopkins scientists

Three European medical centers planning upgrades to Elekta's stereotactic radiosurgery system for the brain

Activating bacterial receptors boosts macrophage response, limits damage to spinal cord following injury

Connexient, RWJUH announce public launch of MediNav Navigator Edition 2.0

Potential molecular link identified between excess fat in the blood and blood vessel recovery in ischemia

Retrosplenial cortex serves as 'conjunction junction' for brain's navigation function

Tillotts Pharma to purchase global rights for AstraZeneca’s Entocort excluding the U.S.

New UCLA study reveals genetic architecture of schizophrenia

Janssen-sponsored Phase 2b trial shows guselkumab effective in treating moderate to severe plaque psoriasis

EvoRx Technologies, AstraZeneca successfully complete research collaboration

Johns Hopkins, IOCB Prague sign drug discovery research agreement

Event guide: 2nd Neuroscience Innovation Partnering & Licensing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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