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Study finds link between long-term dietary patterns and human gut bacteria

"You are what you eat" is familiar enough, but how deep do the implications go? An interdisciplinary group of investigators from the Perelman School of Medicine at the University of Pennsylvania have found an association between long-term dietary patterns and the bacteria of the human gut.

3 Sep 2011

Plerixafor drug shows promise against WHIM syndrome

A new study reports that a drug already approved by the Food and Drug Administration for use in patients undergoing a bone marrow transplant may also have promise for treating people who have a rare immune deficiency known as WHIM syndrome.

3 Sep 2011

New IDSA/PIDS guidelines can thwart pneumonia in children

Immunizations, including a yearly flu vaccine, are the best way to protect children from life-threatening pneumonia, according to new guidelines from the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America.

2 Sep 2011

Further acne treatment studies necessary: Experts

Researchers writing in the journal The Lancet suggest further research that is urgently needed for effective non-antibiotic treatments for acne, because of concerns regarding long-term antibiotic use and its contribution to bacterial resistance. Pharmacies are well stocked with a wide range of acne medications. However, evidence regarding their efficacy and which treatments work best for whom are limited, the authors added.

31 Aug 2011

Stanford method identifies essential regions of Caulobacter's genome

A team at the Stanford University School of Medicine has cataloged, down to the letter, exactly what parts of the genetic code are essential for survival in one bacterial species, Caulobacter crescentus.

31 Aug 2011

Scientists using molecular epidemiology to diagnose and track disease outbreaks

The New York Times examines "new methods of quickly sequencing entire microbial genomes that are revolutionizing the field" of molecularly epidemiology and could help public health officials identify and track disease outbreaks.

31 Aug 2011

Study may help explain plague's rapid evolution and aid in development of therapeutics

In the evolutionary blink of an eye, a bacterium that causes mild stomach irritation evolved into a deadly assassin responsible for the most devastating pandemics in human history. How did the mild-mannered Yersinia pseudotuberculosis become Yersinia pestis, more commonly known as the Plague?

30 Aug 2011

Affinium closes $15 million financing round

Affinium Pharmaceuticals announced today the closing of its $15 million financing. Investors participating in the financing include all three of Affinium's Series A investors, SV Life Sciences, Genesis Capital Partners and Forward Ventures, along with the addition of the Ontario Emerging Technologies Fund (OETF) to the syndicate.

29 Aug 2011

Colchicine more effective than placebo for recurrent pericarditis

Colchicine, when given in addition to conventional therapy, was more effective than placebo in reducing the incidence of recurrence and the persistence of symptoms of pericarditis in a randomised controlled trial.

29 Aug 2011

Azithromycin can help reduce wheezing, other acute symptoms of COPD

A common antibiotic can help reduce the severe wheezing and other acute symptoms of chronic obstructive pulmonary disease, according to a large, multicenter clinical trial sponsored by the National Institutes of Health and conducted at the University of California, San Francisco (UCSF).

29 Aug 2011

Babies, toddlers with congenital heart disease more likely to have harmful toxins after surgery

Babies and toddlers with congenital heart disease are at an increased risk of having harmful toxins in their blood, particularly following surgery, according to research by a team at Imperial College London.

26 Aug 2011

Cholera strain associated with latest pandemic originated in Bangladesh, researchers report

"A cholera pandemic that has swept poor countries in three waves over nearly four decades has been traced to a bacterial strain that first emerged in Bangladesh, scientists reported on Wednesday," Agence France-Presse reports.

26 Aug 2011

Insight into how bacterial toxins cause human diseases may help improve treatment

A better understanding of how bacterial toxins cause common human diseases may lead to their improved treatment and prevention according to a paper just published by Irish and US scientists in Nature Reviews Microbiology.

25 Aug 2011

Redesigned vancomycin can kill deadliest antibiotic-resistant bacteria

A team of scientists from The Scripps Research Institute have successfully reengineered an important antibiotic to kill the deadliest antibiotic-resistant bacteria.

25 Aug 2011

New way to combat dengue fever

The spread of Dengue fever in northern Australia may be controlled by a bacterium that infects mosquitoes that harbor the virus, Australian and U.S. researchers report Aug. 25 in two papers published in the journal Nature.

25 Aug 2011

Cone Health uses Xenex room disinfection systems to reduce HAI rates and costs

Cone Health today announced a dramatic reduction in healthcare-acquired infection (HAIs) rates after implementing an infection prevention program which includes Xenex room disinfection systems.

25 Aug 2011

Researchers trace source of latest cholera pandemic

Researchers have used next generation sequencing to trace the source and explain the spread of the latest (seventh) cholera pandemic. They have also highlighted the impact of the acquisition of resistance to antibiotics on shaping outbreaks and show resistance was first acquired around 1982.

25 Aug 2011

Researchers discover NPC1 protein as crucial for Ebola virus to enter host cells

Although outbreaks are rare, Ebola virus, the cause of Ebola hemorrhagic fever (EHF), is one of the deadliest known viruses affecting humans. According to the World Health Organization (WHO), approximately 1,850 EHF cases with more than 1,200 deaths have been documented since the virus was identified in 1976.

25 Aug 2011

Azithromycin can effectively reduce acute COPD exacerbations

A common antibiotic added to the usual treatment plan for some patients with chronic obstructive pulmonary disease can reduce acute exacerbations — sudden onsets of worsened cough, wheezing and labored breathing — and improve quality of life, according to findings from the COPD Clinical Research Network reported in the Aug. 25, 2011, issue of the New England Journal of Medicine.

25 Aug 2011

Bacteria tweak their genes and proteins to gain strength

Scientists have discovered that bacteria like E. coli and Salmonella have a sneaky way of making minor alterations to their genes to boost their chances for infection.

24 Aug 2011