Neuroscience News and Research

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Strategy-based cognitive training improves cognitive, psychological health after traumatic brain injury

In the first study of its kind, veterans and civilians with traumatic brain injury showed improved cognitive performance and psychological and neural health following strategy-based cognitive training. The Department of Defense-funded study, published this week in Neuropsychological Rehabilitation, was conducted by an interdisciplinary team of cognitive neuroscientists, rehabilitation specialists, and neuroimaging experts from the Center for BrainHealth at The University of Texas at Dallas.

29 May 2015

Therapy for genetically-caused emphysema slows progression of lung disease

A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.

29 May 2015

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Sanford-Burnham Medical Research Institute at Lake Nona today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.

29 May 2015

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

A new collaborative study led by researchers at Sanford-Burnham Medical Research Institute, published today in Cell Reports, provides new insight into the molecular changes that lead to resistance to a commonly prescribed group of drugs called BRAF inhibitors.

28 May 2015

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the initiation of CALLISTO, a new comprehensive clinical research program for their novel oral anticoagulant, rivaroxaban, in patients with active cancer. The studies are evaluating the medicine for the prevention and treatment of life-threatening blood clots in patients with a wide range of cancer types.

28 May 2015

People with MS have much greater risk of dying younger compared to people without MS

New research suggests people with multiple sclerosis (MS) may have double the risk of dying early compared to people without MS, with those younger than 59 at a three times higher risk. The study is published in the May 27, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 May 2015

Electric brain stimulation may improve short-term memory in individuals with schizophrenia

Lightly stimulating the brain with electricity may improve short-term memory in people with schizophrenia, according to a new study by researchers at the Johns Hopkins University School of Medicine.

28 May 2015

Progression of different types of breast cancer influenced differently by tumor microenvironment

Our environment can have a major impact on how we develop, and it turns out it's no different for cancer cells. In work published today in Neoplasia, a team of researchers led by Associate Professor Mikala Egeblad at Cold Spring Harbor Laboratory found that two different mouse models of breast cancer progressed differently based on characteristics of the tumor microenvironment - the area of tissue in which the tumor is embedded.

28 May 2015

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Autism Spectrum Disorder (ASD) is a neurological condition that affects approximately two percent of people around the world. Although several genes have been linked to multiple concurring conditions of ASD, the process that explains how specific genetic variants lead to behaviors characteristic of the disorder remains elusive.

27 May 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

Tiny drug-delivery system can help identify brain tumor types through 'virtual biopsies'

Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through "virtual biopsies" and then attack the molecular structure of the disease.

27 May 2015

DNA changes during drug withdrawal may offer promising ways to develop effective addiction treatments

One of the major challenges of cocaine addiction is the high rate of relapse after periods of withdrawal and abstinence. But new research reveals that changes in our DNA during drug withdrawal may offer promising ways of developing more effective treatments for addiction.

27 May 2015

Canadian researchers shed light on molecular dynamics of chronic pain

Chronic pain affects hundreds of millions of people worldwide and is a major cause of disability, causing more disability than cancer and heart disease. Canadian researchers, including Michael Salter at SickKids are shedding light on the molecular dynamics of chronic pain. They have uncovered a critical role for a class of cells present in the brain and spinal cord, called microglia, in pain.

27 May 2015

Researchers make important breakthrough in identifying major drivers of excessive coughing

Cough treatments could change dramatically after the herpes virus helped researchers discover that the respiratory tract links to two different parts of the nervous system.

27 May 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Roche announced today that the US Food and Drug Administration has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens.

26 May 2015

Previous motherhood alters cognition, neuroplasticity in response to hormone therapy

Hormone therapy (HT) is prescribed to alleviate some of the symptoms of menopause in women. Menopausal women are more likely to be diagnosed with Alzheimer's disease but not other forms of dementia, and HT has been prescribed to treat cognitive decline in post-menopausal women with variable degrees of effectiveness.

26 May 2015

Oscillations could play role in resetting sensitivity of neurons after eye movements

Scientists measuring brain activity have found that in many regions, such as the sensory or motor cortex, activity sometimes oscillates at different frequencies, forming wave-like patterns. Despite the fact that such oscillations are frequently observed, and present in many brain regions, their functional role remains unclear.

26 May 2015

Researchers create 'brainstorm barometer' to calculate the brain functions of very premature infants

University of Helsinki researchers have partnered with Swedish and Australian researchers to create a "brainstorm barometer", which allows computers to calculate the brain functions of very premature babies during their first hours of life.

25 May 2015

Echolocators use echoes to detect multiple properties of objects through visual areas of the brain

Certain blind individuals have the ability to use echoes from tongue or finger clicks to recognize objects in the distance, and some use echolocation as a replacement for vision. Research done by Dr. Mel Goodale, from the University of Western Ontario, in Canada, and colleagues around the world, is showing that echolocation in blind individuals is a full form of sensory substitution, and that blind echolocation experts recruit regions of the brain normally associated with visual perception when making echo-based assessments of objects.

25 May 2015

Neuroscience News and Research

Strategy-based cognitive training improves cognitive, psychological health after traumatic brain injury

Therapy for genetically-caused emphysema slows progression of lung disease

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

People with MS have much greater risk of dying younger compared to people without MS

Electric brain stimulation may improve short-term memory in individuals with schizophrenia

Progression of different types of breast cancer influenced differently by tumor microenvironment

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

Tiny drug-delivery system can help identify brain tumor types through 'virtual biopsies'

DNA changes during drug withdrawal may offer promising ways to develop effective addiction treatments

Canadian researchers shed light on molecular dynamics of chronic pain

Researchers make important breakthrough in identifying major drivers of excessive coughing

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Previous motherhood alters cognition, neuroplasticity in response to hormone therapy

Oscillations could play role in resetting sensitivity of neurons after eye movements

Researchers create 'brainstorm barometer' to calculate the brain functions of very premature infants

Echolocators use echoes to detect multiple properties of objects through visual areas of the brain

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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