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Scientists restore partial hearing and balance in deaf mice using new gene therapy

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

28 Jan 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Single-molecule compounds may become basis for new antioxidant therapies

Treated particles of graphene derived from carbon nanotubes have demonstrated remarkable potential as life-saving antioxidants, but as small as they are, something even smaller had to be created to figure out why they work so well.

28 Jan 2017

Study shows evidence that intestinal microorganisms can serve as link between diet and colorectal cancer

A new study provides some of the strongest evidence to date that microorganisms living in the large intestine can serve as a link between diet and certain types of colorectal cancer, the lead authors at Dana-Farber Cancer Institute and Massachusetts General Hospital report.

28 Jan 2017

Premature infants do not show brain response to expectations that may be key to neural development

Babies born prematurely don't use their expectations about the world to shape their brains as babies born at full term do, important evidence that this neural process is important to development.

27 Jan 2017

Joslin scientists suggest new approach to improve stroke therapy

The standard of care for treating strokes caused by blood clots involves the therapeutic infusion of tissue plasminogen activator (tPA), which can help to dissolve the clots and restore blood flow.

27 Jan 2017

Penn researchers shed new light on potential causes of premature birth

Depending on the specific type, bacteria in a woman's vagina and cervix may increase the risk of premature birth or protect against it, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jan 2017

Quality improvement interventions in hospitals linked to reduced Cesarean delivery rate

A new study led by clinician-researchers at Beth Israel Deaconess Medical Center has found that hospital-led interventions over a seven-year period were associated with a significant reduction in the hospital's Cesarean delivery rate.

27 Jan 2017

Study: Personalised risk information and taster sessions double chances of attending stop smoking course

Offering smokers a taster session at an NHS Stop Smoking Service and explaining their personal risk of developing smoking-related diseases doubles their likelihood of attending a stop smoking course, according to a study in The Lancet.

27 Jan 2017

Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

Parkinson's disease (PD) and other "synucleinopathies" are known to be linked to the misfolding of alpha-synuclein protein in neurons.

27 Jan 2017

Body shaming may contribute to increased health risks

Body shaming is a pervasive form of prejudice, found in cyber bullying, critiques of celebrities' appearances, at work and school, and in public places for everyday Americans.

27 Jan 2017

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

27 Jan 2017

Smartphone app reduces length of hospital stay after delivery for C-section patients

Women who used a smartphone app as part of a Perioperative Surgical Home (PSH) program were released from the hospital sooner after delivering their babies via cesarean section, according to a study presented at the American Society of Anesthesiologists PRACTICE MANAGEMENT 2017 meeting.

27 Jan 2017

NIH scientists improve understanding of antibody-based protection against klebsiella bacteria

Klebsiella bacteria cause about 10 percent of all hospital-acquired infections in the United States. K. pneumoniae sequence type 258 (ST258) is one of the Carbapenem-Resistant Enterobacteriaceae organisms labeled an urgent threat by the Centers for Disease Control and Prevention.

27 Jan 2017

Combination assessment may rule out presence of OSA in children with Down syndrome

A combination of parental questionnaires and inexpensive diagnostic procedures that can be performed as part of a primary care visit may be able to rule out the presence of obstructive sleep apnea in people with Down syndrome.

26 Jan 2017

Adelaide researchers uncover new pathway that regulates spread of prostate cancer

University of Adelaide researchers have uncovered a new pathway which regulates the spread of prostate cancer around the body.

26 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.

25 Jan 2017

Portable DNA sequencing device brought into North Hospitals to fight against anti-microbial resistance

A cutting edge, portable DNA sequencing device is being brought into North Hospitals for the first time by scientists fighting against anti-microbial resistance.

From Oxford Nanopore Technologies 25 Jan 2017

Functional MRI brain scan may help predict patient’s response to antidepressant therapy

A functional MRI brain scan may help predict which patients will respond positively to antidepressant therapy, according to a new study published in the journal Brain.

25 Jan 2017

Medical School News and Research

Scientists restore partial hearing and balance in deaf mice using new gene therapy

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Single-molecule compounds may become basis for new antioxidant therapies

Study shows evidence that intestinal microorganisms can serve as link between diet and colorectal cancer

Premature infants do not show brain response to expectations that may be key to neural development

Joslin scientists suggest new approach to improve stroke therapy

Penn researchers shed new light on potential causes of premature birth

Quality improvement interventions in hospitals linked to reduced Cesarean delivery rate

Study: Personalised risk information and taster sessions double chances of attending stop smoking course

Researchers shed light on basis of Parkinson’s disease and other ‘synucleinopathies’

Body shaming may contribute to increased health risks

Novel gene therapy restores partial hearing and balance in mice born with genetic deafness

Smartphone app reduces length of hospital stay after delivery for C-section patients

NIH scientists improve understanding of antibody-based protection against klebsiella bacteria

Combination assessment may rule out presence of OSA in children with Down syndrome

Adelaide researchers uncover new pathway that regulates spread of prostate cancer

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Portable DNA sequencing device brought into North Hospitals to fight against anti-microbial resistance

Functional MRI brain scan may help predict patient’s response to antidepressant therapy

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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